PDBsum entry 1vl4

Go to PDB code: 
protein Protein-protein interface(s) links
Gene regulation PDB id
Protein chains
429 a.a. *
Waters ×493
* Residue conservation analysis
PDB id:
Name: Gene regulation
Title: Crystal structure of a putative modulator of a DNA gyrase (t from thermotoga maritima msb8 at 1.95 a resolution
Structure: Pmba-related protein. Chain: a, b. Engineered: yes
Source: Thermotoga maritima. Organism_taxid: 243274. Strain: msb8. Gene: tm0727. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Dimer (from PQS)
1.95Å     R-factor:   0.176     R-free:   0.221
Authors: Joint Center For Structural Genomics (Jcsg)
Key ref:
C.Rife et al. (2005). Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold. Proteins, 61, 444-448. PubMed id: 16104019 DOI: 10.1002/prot.20468
09-Jul-04     Release date:   21-Sep-04    
Go to PROCHECK summary

Protein chains
Pfam   ArchSchema ?
Q9WZI6  (Q9WZI6_THEMA) -  Peptidase U62 modulator of DNA gyrase
435 a.a.
429 a.a.
Key:    PfamA domain  Secondary structure  CATH domain


DOI no: 10.1002/prot.20468 Proteins 61:444-448 (2005)
PubMed id: 16104019  
Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold.
C.Rife, R.Schwarzenbacher, D.McMullan, P.Abdubek, E.Ambing, H.Axelrod, T.Biorac, J.M.Canaves, H.J.Chiu, A.M.Deacon, M.DiDonato, M.A.Elsliger, A.Godzik, C.Grittini, S.K.Grzechnik, J.Hale, E.Hampton, G.W.Han, J.Haugen, M.Hornsby, L.Jaroszewski, H.E.Klock, E.Koesema, A.Kreusch, P.Kuhn, S.A.Lesley, M.D.Miller, K.Moy, E.Nigoghossian, J.Paulsen, K.Quijano, R.Reyes, E.Sims, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, A.White, G.Wolf, Q.Xu, K.O.Hodgson, J.Wooley, I.A.Wilson.
No abstract given.

  Selected figure(s)  
Figure 1.
Figure 1. Crystal structure of Thermotoga maritima pmbA. (A) Stereo ribbon diagram of pmbA color-coded from N-terminus (blue) to C-terminus (red) showing the domain organization. Helices H1-H12 and -strands ( 1- 20) are indicated. Disordered regions are depicted by a dashed line. (B) Diagram showing the secondary structure elements in pmbA (chain A) superimposed on its primary sequence. The -helices, 3[10]-helices, -bulges, and -turns are indicated. The -sheet strands are indicated by a red A, B, and C. -Hairpins are depicted as red loops. Disordered regions are depicted by a dashed line with the corresponding sequence in brackets.
Figure 2.
Figure 2. (A) PmbA dimer in ribbon and surface representation with chain A in marine and chain B in orange. (B) PmbA monomer in surface representation colored according to sequence conservation, where green is conserved and white is nonconserved. The two views represent front and backside which corresponds to inside and outside of the pmbA dimer, respectively. (C) PmbA monomer in surface representation (same views as in B) colored according to electrostatic potential, where red is negative and blue is positive.
  The above figures are reprinted by permission from John Wiley & Sons, Inc.: Proteins (2005, 61, 444-448) copyright 2005.