PDBsum entry: 1vl2

Ligase

PDB id: 1vl2

Contents

Protein chains

398 a.a. *

Waters ×1184

* Residue conservation analysis

PDB id:

1vl2

Name:

Ligase

Title:

Crystal structure of argininosuccinate synthase (tm1780) fro thermotoga maritima at 1.65 a resolution

Structure:

Argininosuccinate synthase. Chain: a, b, c, d. Synonym: citrulline--aspartate ligase. Engineered: yes

Source:

Thermotoga maritima. Organism_taxid: 2336. Gene: argg, tm1780. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Tetramer (from PQS)

Resolution:

1.65Å R-factor: 0.179 R-free: 0.209

Authors:

Joint Center For Structural Genomics (Jcsg)

Key ref:

Joint center for structural genomics (jcsg) Crystal structure of argininosuccinate synthase (tm1780) from thermotoga maritima at 1.65 a resolution. To be published,

Date:

08-Jul-04 Release date: 17-Aug-04

Protein chains

Q9X2A1  (ASSY_THEMA) -  Argininosuccinate synthase

Seq: 409 a.a.

Struc: 398 a.a.

Enzyme reactions

• Enzyme class: E.C.6.3.4.5 - Argininosuccinate synthase.
• Pathway: Urea Cycle and Arginine Biosynthesis
• Reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)- (L-arginino)succinate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: cytoplasm (1 term)
• Biological process: cellular amino acid biosynthetic process (2 terms)
• Biochemical function: nucleotide binding (4 terms)