PDBsum entry: 1ve4

Transferase

PDB id

1ve4

Contents

			Protein chain

					201 a.a. *

			Ligands

					SO4


					GOL

			Waters ×242

* Residue conservation analysis

PDB id:

1ve4

Links
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Name:

Transferase

Title:

Atp-phosphoribosyltransferase(hisg) from thermus thermophilu

Structure:

Atp phosphoribosyltransferase. Chain: a. Engineered: yes

Source:

Thermus thermophilus. Organism_taxid: 274. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.20Å

R-factor:

0.230

R-free:

0.247

Authors:

R.Omi,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

R.Omi et al. Crystal structure of atp-Phosphoribosyltransferase(hisg). To be published,

Date:

27-Mar-04

Release date:

21-Jun-05

PROCHECK

	Headers

	References

Protein chain

P62381 (HIS1_THET2) - ATP phosphoribosyltransferase

Seq: Struc:					206 a.a. 201 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.2.4.2.17 - Atp phosphoribosyltransferase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Pathway:

Histidine Biosynthesis (early stages)

Reaction:

1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D- ribose 1-diphosphate

1-(5-phospho-D-ribosyl)-ATP	+	diphosphate	=	ATP	+	5-phospho-alpha-D- ribose 1-diphosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site



		Gene Ontology (GO) functional annotation

Cellular component	cytoplasm	1 term
Biological process	cellular amino acid biosynthetic process	2 terms
Biochemical function	nucleotide binding	5 terms