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PDBsum entry 1vdk

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protein Protein-protein interface(s) links
Lyase PDB id
1vdk
Jmol
Contents
Protein chains
458 a.a. *
Waters ×648
* Residue conservation analysis
PDB id:
1vdk
Name: Lyase
Title: Crystal structure of fumarase from thermus thermophilus hb8
Structure: Fumarate hydratase class ii. Chain: a, b. Synonym: fumarasE C. Engineered: yes. Mutation: yes
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Biol. unit: Tetramer (from PDB file)
Resolution:
1.80Å     R-factor:   0.185     R-free:   0.201
Authors: H.Mizutani,N.Kunishima,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: H.Mizutani and n.kunishima Crystal structure of fumarase from thermus thermophilus hb8. To be published, .
Date:
23-Mar-04     Release date:   13-Apr-04    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P84127  (P84127_THETH) -  Fumarate hydratase class II
Seq:
Struc:
466 a.a.
458 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.2  - Fumarate hydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Citric acid cycle
      Reaction: (S)-malate = fumarate + H2O
(S)-malate
= fumarate
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   2 terms 
  Biological process     fumarate metabolic process   2 terms 
  Biochemical function     catalytic activity     3 terms