PDBsum entry 1up5

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protein metals Protein-protein interface(s) links
Signalling protein PDB id
Protein chains
145 a.a. *
_CA ×8
Waters ×231
* Residue conservation analysis
PDB id:
Name: Signalling protein
Title: Chicken calmodulin
Structure: Calmodulin. Chain: a, b
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Organ: gizzard. Tissue: smooth muscle
1.9Å     R-factor:   0.208     R-free:   0.259
Authors: M.A.Wilson,B.Rupp
Key ref:
B.Rupp et al. (1996). Crystallization and preliminary X-ray analysis of two new crystal forms of calmodulin. Acta Crystallogr D Biol Crystallogr, 52, 411-413. PubMed id: 15299715 DOI: 10.1107/S0907444995011826
27-Sep-03     Release date:   24-Mar-05    
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Protein chains
Pfam   ArchSchema ?
P62149  (CALM_CHICK) -  Calmodulin
149 a.a.
145 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     vesicle   12 terms 
  Biological process     regulation of cytokinesis   13 terms 
  Biochemical function     ion channel binding     12 terms  


DOI no: 10.1107/S0907444995011826 Acta Crystallogr D Biol Crystallogr 52:411-413 (1996)
PubMed id: 15299715  
Crystallization and preliminary X-ray analysis of two new crystal forms of calmodulin.
B.Rupp, D.R.Marshak, S.Parkin.
Two new crystal forms of calmodulin from Gallus gallus are reported. Crystals in space group P1 (cell dimensions a = 59.7, b = 53.1, c = 24.6 A, alpha = 93.2, beta = 96.7, gamma = 89.2 and Z = 2), grow as long thin needles. Water content on density considerations is approximately 50%. They diffract to approximately 2.0 A but give wide multiply peaked spot profiles. Crystals in space group P2(1)2(1)2(1) (cell dimensions a = 32.2, b = 56.0, c = 67.3 A and Z = 4), grow as clusters of thin tablets and contain approximately 30% water by volume. These small crystals ( approximately 0.4 x 0.15 x 0.1 mm) diffracted well to approximately 1.4 A and some appreciable intensities were observed at resolutions better than 1.2 A.

Literature references that cite this PDB file's key reference

  PubMed id Reference
19821578 G.Loving, and B.Imperiali (2009).
Thiol-reactive derivatives of the solvatochromic 4-N,N-dimethylamino-1,8-naphthalimide fluorophore: a highly sensitive toolset for the detection of biomolecular interactions.
  Bioconjug Chem, 20, 2133-2141.  
18284662 V.Majava, M.V.Petoukhov, N.Hayashi, P.Pirilä, D.I.Svergun, and P.Kursula (2008).
Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure.
  BMC Struct Biol, 8, 10.  
17942116 J.T.Warren, Q.Guo, and W.J.Tang (2007).
A 1.3-A structure of zinc-bound N-terminal domain of calmodulin elucidates potential early ion-binding step.
  J Mol Biol, 374, 517-527.
PDB code: 2pq3
  17438121 K.Dunlap (2007).
Calcium channels are models of self-control.
  J Gen Physiol, 129, 379-383.  
  17671360 P.Kursula, and V.Majava (2007).
A structural insight into lead neurotoxicity and calmodulin activation by heavy metals.
  Acta Crystallogr Sect F Struct Biol Cryst Commun, 63, 653-656.
PDB codes: 2v01 2v02
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