PDBsum entry: 1ujx

Hydrolase,transferase

PDB id: 1ujx

Contents

Protein chain

119 a.a. *

* Residue conservation analysis

PDB id:

1ujx

Name:

Hydrolase,transferase

Title:

The forkhead associated (fha) domain like structure from mouse polynucleotide kinase 3'-phosphatase

Structure:

Polynucleotide kinase 3'-phosphatase. Chain: a. Fragment: fha domain. Engineered: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: riken cdna 1810009g08. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

T.Tomizawa,S.Koshiba,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

T.Tomizawa et al. The forkhead associated (fha) domain like structure from mouse polynucleotide kinase 3'-Phosphatase. To be published,

Date:

12-Aug-03 Release date: 12-Feb-04

Protein chain

Q9JLV6  (PNKP_MOUSE) -  Bifunctional polynucleotide phosphatase/kinase

Seq: 522 a.a.

Struc: 119 a.a.*

* PDB and UniProt seqs differ at 6 residue positions (black crosses)

Enzyme reactions

• Enzyme class 2: E.C.2.7.1.78 - Polynucleotide 5'-hydroxyl-kinase.
• Reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA
• Enzyme class 3: E.C.3.1.3.32 - Polynucleotide 3'-phosphatase.
• Reaction: A 3'-phosphopolynucleotide + H₂O = a polynucleotide + phosphate

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site