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Hydrolase PDB id
1twl
Jmol
Contents
Protein chain
172 a.a. *
Waters ×35
* Residue conservation analysis
PDB id:
1twl
Name: Hydrolase
Title: Inorganic pyrophosphatase from pyrococcus furiosus pfu-26409
Structure: Inorganic pyrophosphatase. Chain: a. Synonym: pyrophosphate phospho-hydrolase, ppase. Engineered: yes
Source: Pyrococcus furiosus. Organism_taxid: 2261. Gene: ppa, pf0257. Expressed in: escherichia coli. Expression_system_taxid: 562
Biol. unit: Hexamer (from PQS)
Resolution:
2.20Å     R-factor:   0.197     R-free:   0.257
Authors: W.Zhou,W.Tempel,Z.-J.Liu,L.Chen,L.-L.Clancy Kelley,B.D.Dilla R.C.Hopkins,W.B.Arendall Iii,J.P.Rose,J.C.Eneh,R.C.Hopkins, F.E.Jenney Jr.,H.S.Lee,T.Li,F.L.Poole Ii,C.Shah,F.J.Sugar, M.W.W.Adams,J.S.Richardson,D.C.Richardson,B.-C.Wang,Southea Collaboratory For Structural Genomics (Secsg)
Key ref: W.Zhou et al. Inorganic pyrophosphatase from pyrococcus furiosus pfu-264096-001. To be published,
Date:
01-Jul-04     Release date:   23-Nov-04    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q8U438  (IPYR_PYRFU) -  Inorganic pyrophosphatase
Seq:
Struc:
178 a.a.
172 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.6.1.1  - Inorganic diphosphatase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Diphosphate + H2O = 2 phosphate
Diphosphate
+ H(2)O
= 2 × phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   1 term 
  Biological process     phosphate metabolic process   1 term 
  Biochemical function     hydrolase activity     4 terms