PDBsum entry: 1tqs

Hydrolase

PDB id: 1tqs

Contents

Protein chain

1014 a.a. *

Ligands

NAG

SSO

MRD

Metals

_ZN

Waters ×1131

* Residue conservation analysis

PDB id:

1tqs

Name:

Hydrolase

Title:

Golgi alpha-mannosidase ii in complex with salacinol

Structure:

Alpha-mannosidase ii. Chain: a. Fragment: family 38 catalytic domain. Synonym: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase golgi alpha-mannosidase ii, aman ii. Engineered: yes. Mutation: yes

Source:

Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: alpha-man-ii, gmii, cg18474/cg18802/cg8139. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell_line: s2 cells

Resolution:

1.30Å R-factor: 0.163 R-free: 0.182

Authors:

D.A.Kuntz,A.Ghavami,B.D.Johnston,B.M.Pinto,D.R.Rose

Key ref:

D.A.Kuntz et al. (2005). Crystallographic analysis of the interactions of drosophila melanogaster golgi alpha-Mannosidase ii with the naturally occurring glycomimetic salacinol and its analogues. Tetrahedron asymmetry, 16, 25-32.