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PDBsum entry 1tp5

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protein ligands links
Peptide binding protein PDB id
1tp5
Jmol
Contents
Protein chain
115 a.a. *
Ligands
LYS-LYS-GLU-THR-
TRP-VAL
Waters ×187
* Residue conservation analysis
PDB id:
1tp5
Name: Peptide binding protein
Title: Crystal structure of pdz3 domain of psd-95 protein complexed with a peptide ligand kketwv
Structure: Presynaptic density protein 95. Chain: a. Fragment: third pdz domain (residues 302-402). Synonym: psd-95, presynaptic protein sap90, synapse- associated protein 90, discs, large homolog 4. Engineered: yes. Lys-lys-glu-thr-trp-val peptide ligand. Chain: b. Engineered: yes
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized
Biol. unit: Dodecamer (from PQS)
Resolution:
1.54Å     R-factor:   0.193     R-free:   0.229
Authors: D.Saro,Z.Wawrzak,P.Martin,J.Vickrey,A.Paredes,L.Kovari, M.Spaller
Key ref: D.Saro et al. Structure of the third pdz domain of psd-95 protein complexed with kketwv peptide ligand. To be published, .
Date:
15-Jun-04     Release date:   20-Sep-05    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P31016  (DLG4_RAT) -  Disks large homolog 4
Seq:
Struc:
 
Seq:
Struc:
724 a.a.
115 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 14 residue positions (black crosses)