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PDBsum entry 1tp3

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protein ligands links
Protein binding PDB id
1tp3
Jmol
Contents
Protein chain
115 a.a. *
Ligands
LYS-LYS-GLU-THR-
PRO-VAL
Waters ×66
* Residue conservation analysis
PDB id:
1tp3
Name: Protein binding
Title: Pdz3 domain of psd-95 protein complexed with kketpv peptide ligand
Structure: Presynaptic density protein 95. Chain: a. Fragment: pdz 3. Residues 302-402. Synonym: psd-95, presynaptic protein sap90, synapse- associated protein 90, discs, large homolog 4. Engineered: yes. Kketpv peptide ligand. Chain: b. Engineered: yes
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: dlg4, dlgh4, psd95. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell_line: gold de3. Synthetic: yes. Other_details: the kketpv peptide ligand was chemically
Biol. unit: Dodecamer (from PQS)
Resolution:
1.99Å     R-factor:   0.228     R-free:   0.296
Authors: D.Saro,P.Martin,J.R.Vickrey,A.Griffin,L.C.Kovari,M.R.Spaller
Key ref: D.Saro et al. Structure of the third pdz domain of psd-95 protein complexed with kketpv peptide ligand. To be published, .
Date:
15-Jun-04     Release date:   20-Sep-05    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P31016  (DLG4_RAT) -  Disks large homolog 4
Seq:
Struc:
 
Seq:
Struc:
724 a.a.
115 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 14 residue positions (black crosses)