PDBsum entry: 1sq1

Lyase

PDB id: 1sq1

Contents

Protein chain

288 a.a. *

Ligands

SO4 ×2

Waters ×7

* Residue conservation analysis

PDB id:

1sq1

Name:

Lyase

Title:

Crystal structure of the chorismate synthase from campylobac jejuni, northeast structural genomics target br19

Structure:

Chorismate synthase. Chain: a. Synonym: 5-enolpyruvylshikimate-3-phosphate phospholyase. Engineered: yes

Source:

Campylobacter jejuni. Organism_taxid: 197. Strain: nctc 11168. Gene: aroc or cj1634. Expressed in: escherichia coli. Expression_system_taxid: 562.

Biol. unit:

Tetramer (from PDB file)

Resolution:

2.80Å R-factor: 0.224 R-free: 0.279

Authors:

F.Forouhar,I.Lee,S.M.Vorobiev,R.Xiao,T.B.Acton,G.T.Montelion J.F.Hunt,Northeast Structural Genomics Consortium (Nesg)

Key ref:

F.Forouhar et al. Crystal structure of the chorismate synthase from campylobacter jejuni, Northeast structural genomics target br19. To be published,

Date:

17-Mar-04 Release date: 06-Apr-04

Protein chain

Q9PM41  (AROC_CAMJE) -  Chorismate synthase

Seq: 362 a.a.

Struc: 288 a.a.

Enzyme reactions

• Enzyme class: E.C.4.2.3.5 - Chorismate synthase.
• Pathway: Shikimate and Chorismate Biosynthesis
• Reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
• Cofactor: FMN

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Biological process: cellular amino acid biosynthetic process (2 terms)
• Biochemical function: protein binding (3 terms)