PDBsum entry: 1s55

Cytokine

PDB id: 1s55

Contents

Protein chains

156 a.a. *

Metals

_CL ×3

Waters ×215

* Residue conservation analysis

PDB id:

1s55

Name:

Cytokine

Title:

Mouse rankl structure at 1.9a resolution

Structure:

Tumor necrosis factor ligand superfamily member 11. Chain: a, b, c. Fragment: residues 161-316. Synonym: receptor activator of nuclear factor kappa b ligand, rankl, tnf-related activation-induced cytokine, trance, osteoprotegerin ligand, opgl, osteoclast differentiation factor, odf, osteoclastogenesis-inhibitory factor, ocif.

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: tnfsf11, rankl, trance, opgl. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Trimer (from PQS)

Resolution:

1.90Å R-factor: 0.230 R-free: 0.252

Authors:

M.J.Teale,X.Feug,L.Chen,T.Bice,E.J.Meehan

Key ref:

M.J.Teale et al. Murine rankl extra cellular domain homotrimer structure in space groups p212121 and h3 at 1.9 and 2.6 respectively. To be published,

Date:

19-Jan-04 Release date: 05-Jul-05

Protein chains

O35235  (TNF11_MOUSE) -  Tumor necrosis factor ligand superfamily member 11

Seq: 316 a.a.

Struc: 156 a.a.

 Gene Ontology (GO) functional annotation 

• Cellular component: membrane (1 term)
• Biological process: immune response (1 term)
• Biochemical function: tumor necrosis factor receptor binding (1 term)