PDBsum entry: 1rzo

Hydrolase

PDB id: 1rzo

Contents

Protein chains

259 a.a. *

262 a.a. *

Ligands

GAL ×11

SO4 ×10

Waters ×406

* Residue conservation analysis

PDB id:

1rzo

Name:

Hydrolase

Title:

Agglutinin from ricinus communis with galactoaza

Structure:

Agglutinin. Chain: a, c. Fragment: a chain. Synonym: rca, rrna n-glycosidase. Agglutinin. Chain: b, d. Fragment: b chain. Synonym: rca

Source:

Ricinus communis. Castor bean. Organism_taxid: 3988. Organism_taxid: 3988

Biol. unit:

Tetramer (from PQS)

Resolution:

2.63Å R-factor: 0.225 R-free: 0.276

Authors:

A.G.Gabdoulkhakov,Y.Savochkina,N.Konareva,R.Krauspenhaar,S.S S.V.Nikonov,W.Voelter,C.Betzel,A.M.Mikhailov

Key ref:

A.G.Gabdoulkhakov et al. Structure-Function investigation comlex of agglutinin from ricinus communis with galactoaza. To be published,

Date:

26-Dec-03 Release date: 28-Dec-04

Protein chains

P06750  (AGGL_RICCO) -  Agglutinin

Seq: 564 a.a.

Struc: 259 a.a.

Protein chains

P06750  (AGGL_RICCO) -  Agglutinin

Seq: 564 a.a.

Struc: 262 a.a.

Enzyme reactions

• Enzyme class: Chains A, B, C, D: E.C.3.2.2.22 - rRNA N-glycosylase.
• Reaction: Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.

 Gene Ontology (GO) functional annotation 

• Biological process: negative regulation of translation (1 term)
• Biochemical function: rRNA N-glycosylase activity (1 term)