PDBsum entry: 1r34

Hydrolase

PDB id: 1r34

Contents

Protein chain

1014 a.a. *

Ligands

NAG

LKS

MPD

Metals

_ZN

Waters ×1058

* Residue conservation analysis

PDB id:

1r34

Name:

Hydrolase

Title:

Golgi alpha-mannosidase ii complex with 5-thio-d- mannopyranosylamidinium salt

Structure:

Putative golgi alpha-mannosidase ii. Chain: a. Fragment: catalytic domain (residues 94-1108). Synonym: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase golgi alpha-mannosidase ii, aman ii. Engineered: yes

Source:

Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: alpha-man-ii. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227.

Resolution:

1.95Å R-factor: 0.151 R-free: 0.196

Authors:

D.A.Kuntz,W.Xin,L.M.Kavelekar,D.R.Rose,B.M.Pinto

Key ref:

L.M.Kavelekar et al. (2005). 5-Thio-D-Glycopyranosylamines and their amidinium salts as potential transition-State mimics of glycosyl hydrolases: synthesis, Enzyme inhibitory activities, X-Ray crystallography, And molecular modeling. Tetrahedron asymmetry, 16, 1035-1046.