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PDBsum entry 1r1l

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protein ligands Protein-protein interface(s) links
Hydrolase/hydrolase inhibitor PDB id
1r1l
Jmol
Contents
Protein chain
409 a.a. *
Ligands
ACE-SER-GLU-ALA-
ALA-ALA-SER
NLE-LEU-PHE
NAG ×7
GOL
FOR
Waters ×119
* Residue conservation analysis
PDB id:
1r1l
Name: Hydrolase/hydrolase inhibitor
Title: Structure of dimeric antithrombin complexed with a p14-p9 re loop peptide and an exogenous tripeptide (formyl-norleucine
Structure: Antithrombin-iii. Chain: l, i. Synonym: atiii, pro0309. Antithrombin p14-p9 peptide. Chain: c. Engineered: yes. Exogenous tripeptide formyl-(nle)lf. Chain: d. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: blood. Synthetic: yes. Other_details: this sequence occurs naturally in homo sapie (human).. Synthetic: yes
Biol. unit: Monomer (from PQS)
Resolution:
2.70Å     R-factor:   0.204     R-free:   0.249
Authors: A.Zhou,J.A.Huntington,D.A.Lomas,P.E.Stein,R.W.Carrell
Key ref: A.Zhou et al. Serpins and the design of peptides to block intermolecular beta-Linkages. To be published, .
Date:
24-Sep-03     Release date:   05-Oct-04    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P01008  (ANT3_HUMAN) -  Antithrombin-III
Seq:
Struc:
464 a.a.
409 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   5 terms 
  Biological process     regulation of blood coagulation, intrinsic pathway   8 terms 
  Biochemical function     protein binding     5 terms