PDBsum entry: 1qvn

Cytokine

PDB id: 1qvn

Contents

Protein chains

123 a.a. *

Ligands

FRI ×4

Metals

_ZN ×4

* Residue conservation analysis

PDB id:

1qvn

Name:

Cytokine

Title:

Structure of sp4160 bound to il-2 v69a

Structure:

Interleukin-2. Chain: a, b, c, d. Synonym: il-2, t-cell growth factor, tcgf, aldesleukin. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: il2. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.70Å R-factor: 0.261 R-free: 0.308

Authors:

C.D.Thanos,W.L.Delano,J.A.Wells

Key ref:

C.D.Thanos et al. Structure of sp4160 bound to il-2 V69a. To be published,

Date:

28-Aug-03 Release date: 05-Apr-05

Protein chains

P60568  (IL2_HUMAN) -  Interleukin-2

Seq: 153 a.a.

Struc: 123 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 

• Cellular component: extracellular region (2 terms)
• Biological process: immune response (27 terms)
• Biochemical function: protein binding (8 terms)