PDBsum entry: 1qgd

Transferase

PDB id: 1qgd

Contents

Protein chains

662 a.a. *

Ligands

SO4 ×2

TPP ×2

Metals

_CA ×2

Waters ×1065

* Residue conservation analysis

PDB id:

1qgd

Name:

Transferase

Title:

Transketolase from escherichia coli

Structure:

Protein (transketolase). Chain: a, b. Engineered: yes

Source:

Escherichia coli. Organism_taxid: 562. Cellular_location: cytoplasm. Expressed in: escherichia coli. Expression_system_taxid: 562

Biol. unit:

Dimer (from PQS)

Resolution:

1.90Å R-factor: 0.132 R-free: 0.176

Authors:

M.N.Isupov,J.A.Littlechild

Key ref:

M.N.Isupov et al. Crystal structure of escherichia coli transketolase. To be published,

Date:

23-Apr-99 Release date: 17-Jun-03

Protein chains

P27302  (TKT1_ECOLI) -  Transketolase 1

Seq: 663 a.a.

Struc: 662 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.2.2.1.1 - Transketolase.
• Reaction: Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate
• Cofactor: Thiamine diphosphate

Thiamine diphosphate (Bound ligand (Het Group name = TPP) corresponds exactly)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Biological process: metabolic process (1 term)
• Biochemical function: catalytic activity (4 terms)