PDBsum entry: 1q3l

Structural protein

PDB id: 1q3l

Contents

Protein chain

52 a.a. *

Ligands

GLN-THR-ALA-ARG-MLZ-SER

Waters ×95

* Residue conservation analysis

PDB id:

1q3l

Name:

Structural protein

Title:

Chromodomain of hp1 complexed with histone h3 tail containing monomethyllysine 9.

Structure:

Heterochromatin protein 1. Chain: a. Fragment: sequence database residues 17-76. Synonym: hp1, nonhistone chromosomal protein c1a9 antigen. Engineered: yes. Histone h3. Chain: p. Fragment: tail residues 1-16. Engineered: yes

Source:

Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: su(var)205 or hp1 or cg8409. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide is chemically synthesized. The sequence is naturally found in homo sapiens (human).

Biol. unit:

Dimer (from PQS)

Resolution:

1.64Å R-factor: 0.223 R-free: 0.241

Authors:

S.A.Jacobs,S.Khorasanizadeh

Key ref:

S.A.Jacobs and s.khorasanizadeh Chromodomain of hp1 complexed with histone h3 tail containing monomethyllysine 9. To be published,

Date:

30-Jul-03 Release date: 12-Oct-04

Protein chain

P05205  (HP1_DROME) -  Heterochromatin protein 1

Seq: 206 a.a.

Struc: 52 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 

• Cellular component: nucleus (2 terms)
• Biological process: chromatin assembly or disassembly (1 term)
• Biochemical function: chromatin binding (1 term)