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PDBsum entry 1pbk

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protein ligands links
Isomerase PDB id
1pbk
Jmol
Contents
Protein chain
116 a.a. *
Ligands
RAP
Waters ×150
* Residue conservation analysis
PDB id:
1pbk
Name: Isomerase
Title: Homologous domain of human fkbp25
Structure: Fkbp25. Chain: a. Fragment: fkbp12 homologous domain, residues pro 109 - asp 2. Synonym: fkbp25 c-terminal domain. Ec 5.2.1.8. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21(de3). Gene: human hippocampal cdna library. Expressed in: escherichia coli. Expression_system_taxid: 562. (Clontech, palo alto,ca)
Resolution:
2.50Å     R-factor:   0.185     R-free:   0.243
Authors: J.Liang,D.T.Hung,S.L.Schreiber,J.Clardy
Key ref: J.Liang et al. (1996). Structure of the human 25 kda fk506 binding protein complexed with rapamycin.. J.Am.Chem.Soc., 118, 1231-1232.
Date:
01-Sep-95     Release date:   14-Oct-96    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q00688  (FKBP3_HUMAN) -  Peptidyl-prolyl cis-trans isomerase FKBP3
Seq:
Struc:
224 a.a.
116 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.5.2.1.8  - Peptidylprolyl isomerase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Peptidylproline (omega=180) = peptidylproline (omega=0)
Peptidylproline (omega=180)
= peptidylproline (omega=0)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     protein folding   1 term