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PDBsum entry 1obg

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protein ligands metals links
Ligase PDB id
1obg
Jmol
Contents
Protein chain
305 a.a. *
Ligands
AMP ×2
SO4 ×2
Metals
_MG
Waters ×273
* Residue conservation analysis
PDB id:
1obg
Name: Ligase
Title: Saicar-synthase complexed with atp
Structure: Phosphoribosylamidoimidazole- succinocarboxamide synthase. Chain: a. Synonym: saicar synthetase. Ec: 6.3.2.6
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932
Resolution:
2.05Å     R-factor:   0.168     R-free:   0.206
Authors: S.V.Antonyuk,A.I.Grebenko,V.M.Levdikov,D.V.Urusova, W.R.Melik-Adamyan,V.S.Lamzin,K.Wilson
Key ref: S.V.Antonyuk et al. (2001). X-Ray structure of saicar-Synthase complexed with atp. Kristallografiya, 46, 620.
Date:
30-Jan-03     Release date:   06-Mar-03    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P27616  (PUR7_YEAST) -  Phosphoribosylaminoimidazole-succinocarboxamide synthase
Seq:
Struc:
306 a.a.
305 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.6.3.2.6  - Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
Purine Biosynthesis (late stages)
      Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate
ATP
+ 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
+ L-aspartate
=
ADP
Bound ligand (Het Group name = AMP)
matches with 85.00% similarity
+ phosphate
+ (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     purine nucleotide biosynthetic process   2 terms 
  Biochemical function     nucleotide binding     5 terms