PDBsum entry 1o22

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protein links
Unknown function PDB id
Protein chain
149 a.a.
Waters ×102
PDB id:
Name: Unknown function
Title: Crystal structure of an orphan protein (tm0875) from thermot maritima at 2.00 a resolution
Structure: Orphan protein tm0875. Chain: a. Engineered: yes
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: tm0875. Expressed in: escherichia coli. Expression_system_taxid: 562.
Biol. unit: Dimer (from PDB file)
2.00Å     R-factor:   0.186     R-free:   0.238
Authors: Joint Center For Structural Genomics (Jcsg)
Key ref:
C.Bakolitsa et al. (2004). Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold. Proteins, 56, 607-610. PubMed id: 15229892 DOI: 10.1002/prot.20138
15-Feb-03     Release date:   01-Apr-03    
Go to PROCHECK summary

Protein chain
Pfam   ArchSchema ?
Q9WZX8  (Q9WZX8_THEMA) -  Uncharacterized protein
158 a.a.
149 a.a.
Key:    PfamA domain  Secondary structure  CATH domain


DOI no: 10.1002/prot.20138 Proteins 56:607-610 (2004)
PubMed id: 15229892  
Crystal structure of an orphan protein (TM0875) from Thermotoga maritima at 2.00-A resolution reveals a new fold.
C.Bakolitsa, R.Schwarzenbacher, D.McMullan, L.S.Brinen, J.M.Canaves, X.Dai, A.M.Deacon, M.A.Elsliger, S.Eshagi, R.Floyd, A.Godzik, C.Grittini, S.K.Grzechnik, L.Jaroszewski, C.Karlak, H.E.Klock, E.Koesema, J.S.Kovarik, A.Kreusch, P.Kuhn, S.A.Lesley, T.M.McPhillips, M.D.Miller, A.Morse, K.Moy, J.Ouyang, R.Page, K.Quijano, A.Robb, G.Spraggon, R.C.Stevens, H.van den Bedem, J.Velasquez, J.Vincent, F.von Delft, X.Wang, B.West, G.Wolf, K.O.Hodgson, J.Wooley, I.A.Wilson.
No abstract given.

  Selected figure(s)  
Figure 1.
Figure 1. Crystal structure of TM0875. A: Stereo ribbon diagram of Thermotoga maritima TM0875 color coded from N-terminus (blue) to C-terminus (red) showing the domain organization. Helices (H1-H4) and -strands ( 1- 9) are indicated. B: Diagram showing the secondary structure elements in TM0875 superimposed on its primary sequence with helices labeled consecutively (H1-H4), -sheets A-C labeled in red, and -hairpins indicated in red. The disordered regions are depicted in dashed lines with the corresponding sequence in brackets.
Figure 2.
Figure 2. A: Ribbon diagram of the TM0875 dimer. B: Ribbon diagram of a superposition of TM0875 (grey) and Yggu from E. coli (blue; PDB: 1n91).
  The above figures are reprinted by permission from John Wiley & Sons, Inc.: Proteins (2004, 56, 607-610) copyright 2004.  

Literature references that cite this PDB file's key reference

  PubMed id Reference
17064285 S.B.Conners, E.F.Mongodin, M.R.Johnson, C.I.Montero, K.E.Nelson, and R.M.Kelly (2006).
Microbial biochemistry, physiology, and biotechnology of hyperthermophilic Thermotoga species.
  FEMS Microbiol Rev, 30, 872-905.  
16211521 R.Page, A.M.Deacon, S.A.Lesley, and R.C.Stevens (2005).
Shotgun crystallization strategy for structural genomics II: crystallization conditions that produce high resolution structures for T. maritima proteins.
  J Struct Funct Genomics, 6, 209-217.  
15193310 I.Friedberg, L.Jaroszewski, Y.Ye, and A.Godzik (2004).
The interplay of fold recognition and experimental structure determination in structural genomics.
  Curr Opin Struct Biol, 14, 307-312.  
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