PDBsum entry: 1mqo

Hydrolase

PDB id

1mqo

Contents

			Protein chain

					221 a.a. *

			Ligands

					CIT

			Metals

					_CD ×3

			Waters ×261

* Residue conservation analysis

PDB id:

1mqo

Links
- PDBe
- RCSB
- SRS
- MMDB
- JenaLib
- OCA
- PDBWiki
- Proteopedia
- CATH
- SCOP
- FSSP
- HSSP
- PDBSWS
- PQS
- CSA
- PROCOGNATE
- ProSAT
- EDS
- Whatcheck

Name:

Hydrolase

Title:

Metallo-beta-lactamase bcii cd substituted from bacillus cereus at 1.35 angstroms resolution

Structure:

Beta-lactamase ii. Chain: a. Synonym: penicillinase, cephalosporinase. Engineered: yes

Source:

Bacillus cereus. Organism_taxid: 1396. Gene: blm. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.35Å

R-factor:

0.222

R-free:

0.248

Authors:

I.Garcia-Saez,L.Chantalat,O.Dideberg

Key ref:

I.Garcia-Saez et al. High resolution structure of the cd substituted bcii from bacillus cereus. To be published,

Date:

17-Sep-02

Release date:

18-May-04

PROCHECK

	Headers

	References

Protein chain

P04190 (BLA2_BACCE) - Beta-lactamase 2

Seq: Struc:					257 a.a. 221 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.3.5.2.6 - Beta-lactamase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Pathway:

Penicillin Biosynthesis and Metabolism

Reaction:

A beta-lactam + H₂O = a substituted beta-amino acid

Cofactor:

Zinc



		Gene Ontology (GO) functional annotation

Biological process	response to antibiotic	2 terms
Biochemical function	hydrolase activity	4 terms