PDBsum entry 1ltk

Transferase

PDB id: 1ltk

Contents

Protein chains

417 a.a. *

Ligands

SO4 ×3

AMP ×3

GOL

Waters ×72

* Residue conservation analysis

PDB id:

1ltk

Name:

Transferase

Title:

Crystal structure of phosphoglycerate kinase from plasmodium falciparum, in the open conformation

Structure:

Phosphoglycerate kinase. Chain: a, b, c. Engineered: yes

Source:

Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Gene: pgk. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

3.00Å R-factor: 0.208 R-free: 0.258

Authors:

D.Chattopadhyay,B.Pal,C.D.Smith

Key ref:

D.Chattopadhyay et al. Crystal structure of phosphoglycerate kinase from plasmodium falciparum. To be published, .

Date:

20-May-02 Release date: 29-Jul-03

Protein chains

P27362  (PGK_PLAF7) -  Phosphoglycerate kinase from Plasmodium falciparum (isolate 3D7)

Seq: 416 a.a.

Struc: 417 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.2.7.2.3 - phosphoglycerate kinase.
• Pathway: Calvin Cycle (carbon fixation stages)
• Reaction: (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP

(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate (Bound ligand (Het Group name = AMP) matches with 85.19% similarity) + ADP (Bound ligand (Het Group name = GOL) matches with 40.00% similarity)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site