PDBsum entry: 1l7b

Ligase

PDB id: 1l7b

Contents

Protein chain

92 a.a. *

* Residue conservation analysis

PDB id:

1l7b

Name:

Ligase

Title:

Solution nmr structure of brct domain of t. Thermophilus: northeast structural genomics consortium target wr64tt

Structure:

DNA ligase. Chain: a. Fragment: brct domain. Engineered: yes

Source:

Thermus thermophilus. Organism_taxid: 274. Gene: dnlj. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

NMR struc:

10 models

Authors:

G.Sahota,B.L.Dixon,Y.P.Huang,J.Aramini,D.Monleon, D.Bhattacharya,G.V.T.Swapna,C.Yin,R.Xiao,S.Anderson, R.Tejero,G.T.Montelione,Northeast Structural Genomics Consortium (Nesg)

Key ref:

G.Sahota et al. Solution nmr structure of the brct domain from thermus thermophilus DNA ligase. To be published,

Date:

14-Mar-02 Release date: 16-Sep-03

Protein chain

P26996  (DNLJ_THET8) -  DNA ligase

Seq: 676 a.a.

Struc: 92 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.6.5.1.2 - Dna ligase (NAD(+)).
• Reaction: NAD⁺ + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + nicotinamide nucleotide + (deoxyribonucleotide)(n+m)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: intracellular (1 term)