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PDBsum entry 1kkk

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protein ligands metals links
Hydrolase/hydrolase inhibitor PDB id
1kkk
Jmol
Contents
Protein chain
316 a.a. *
Ligands
PHQ-ASP
Metals
_CA ×4
_ZN
Waters ×189
* Residue conservation analysis
PDB id:
1kkk
Name: Hydrolase/hydrolase inhibitor
Title: Thermolysin complexed with z-l-aspartic acid (benzyloxycarbo aspartic acid)
Structure: Thermolysin. Chain: a. Ec: 3.4.24.27
Source: Bacillus thermoproteolyticus. Organism_taxid: 1427
Biol. unit: Dimer (from PQS)
Resolution:
1.60Å     R-factor:   0.169     R-free:   0.189
Authors: M.Senda,T.Senda,S.Kidokoro
Key ref: M.Senda et al. Crystal structure analyses of thermolysin in complex with its inhibitors.. To be published, .
Date:
10-Dec-01     Release date:   10-Dec-02    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00800  (THER_BACTH) -  Thermolysin
Seq:
Struc:
 
Seq:
Struc:
548 a.a.
316 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.4.24.27  - Thermolysin.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe.
      Cofactor: Ca(2+); Zn(2+)
 Gene Ontology (GO) functional annotation 
  GO annot!
  Biological process     proteolysis   1 term 
  Biochemical function     metalloendopeptidase activity     1 term