PDBsum entry: 1jnm

Transcription/DNA

PDB id: 1jnm

Contents

Protein chains

56 a.a. *

DNA/RNA

Waters ×220

* Residue conservation analysis

PDB id:

1jnm

Name:

Transcription/DNA

Title:

Crystal structure of the jun/cre complex

Structure:

5'- d( Cp Gp Tp Cp Gp Ap Tp Gp Ap Cp Gp Tp Cp Ap Tp Cp Gp Ap Cp G)-3'. Chain: c, d. Engineered: yes. Other_details: camp response element (cre) DNA target. Proto-oncogenE C-jun. Chain: a, b. Fragment: bzip domain.

Source:

Synthetic: yes. Other_details: this sequence occurs naturally in humans.. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Tetramer (from PQS)

Resolution:

2.20Å R-factor: 0.228 R-free: 0.286

Authors:

Y.Kim,L.M.Podust

Key ref:

Y.Kim and l.m.podust Crystal structure of the jun bzip homodimer complexed with cre. To be published,

Date:

24-Jul-01 Release date: 03-Jun-03

Protein chains

P05412  (JUN_HUMAN) -  Transcription factor AP-1

Seq: 331 a.a.

Struc: 56 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

 Gene Ontology (GO) functional annotation 

• Cellular component: nucleus (1 term)
• Biological process: regulation of transcription, DNA-dependent (1 term)
• Biochemical function: transcription factor activity (3 terms)