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Ribosome PDB id
1jgq
Jmol
Contents
Protein chains
234 a.a.* *
206 a.a.* *
208 a.a.* *
150 a.a.* *
101 a.a.* *
155 a.a.* *
138 a.a.* *
127 a.a.* *
98 a.a.* *
119 a.a.* *
124 a.a.* *
125 a.a.* *
60 a.a.* *
88 a.a.* *
83 a.a.* *
104 a.a.* *
73 a.a.* *
80 a.a.* *
99 a.a.* *
24 a.a.* *
DNA/RNA
* Residue conservation analysis
* C-alpha coords only
PDB id:
1jgq
Name: Ribosome
Title: The path of messenger RNA through the ribosome. This file, 1 contains the 30s ribosome subunit, three tRNA, and mRNA mol 50s ribosome subunit is in the file 1giy
Structure: 30s 16s ribosomal RNA. Chain: a. tRNA(phe). Chain: b, c. Engineered: yes. Other_details: a-site tRNA chain b, p-site tRNA chain c. tRNA(phe). Chain: d. Engineered: yes.
Source: Thermus thermophilus. Organism_taxid: 274. Synthetic: yes. Other_details: sequence naturally occurs in saccharomyces cerevisiae. Organism_taxid: 274
Resolution:
5.00Å     R-factor:   not given    
Authors: G.Z.Yusupova,M.M.Yusupov,J.H.D.Cate,H.F.Noller
Key ref:
G.Z.Yusupova et al. (2001). The path of messenger RNA through the ribosome. Cell, 106, 233-241. PubMed id: 11511350 DOI: 10.1016/S0092-8674(01)00435-4
Date:
26-Jun-01     Release date:   20-Jul-01    
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P80371  (RS2_THET8) -  30S ribosomal protein S2
Seq:
Struc: 		256 a.a.
234 a.a.
Protein chain
Pfam   ArchSchema ?
P80373  (RS4_THET8) -  30S ribosomal protein S4
Seq:
Struc: 		209 a.a.
206 a.a.*
Protein chain
Pfam   ArchSchema ?
P80373  (RS4_THET8) -  30S ribosomal protein S4
Seq:
Struc: 		209 a.a.
208 a.a.*
Protein chain
Pfam   ArchSchema ?
Q5SHQ5  (RS5_THET8) -  30S ribosomal protein S5
Seq:
Struc: 		162 a.a.
150 a.a.
Protein chain
Pfam   ArchSchema ?
Q5SLP8  (RS6_THET8) -  30S ribosomal protein S6
Seq:
Struc: 		101 a.a.
101 a.a.
Protein chain
Pfam   ArchSchema ?
P17291  (RS7_THET8) -  30S ribosomal protein S7
Seq:
Struc: 		156 a.a.
155 a.a.
Protein chain
Pfam   ArchSchema ?
Q5SHQ2  (RS8_THET8) -  30S ribosomal protein S8
Seq:
Struc: 		138 a.a.
138 a.a.
Protein chain
Pfam   ArchSchema ?
P80374  (RS9_THET8) -  30S ribosomal protein S9
Seq:
Struc: 		128 a.a.
127 a.a.*
Protein chain
Pfam   ArchSchema ?
Q5SHN7  (RS10_THET8) -  30S ribosomal protein S10
Seq:
Struc: 		105 a.a.
98 a.a.
Protein chain
Pfam   ArchSchema ?
P80376  (RS11_THET8) -  30S ribosomal protein S11
Seq:
Struc: 		129 a.a.
119 a.a.
Protein chain
Pfam   ArchSchema ?
Q5SHN3  (RS12_THET8) -  30S ribosomal protein S12
Seq:
Struc: 		132 a.a.
124 a.a.
Protein chain
Pfam   ArchSchema ?
P80377  (RS13_THET8) -  30S ribosomal protein S13
Seq:
Struc: 		126 a.a.
125 a.a.
Protein chain
Pfam   ArchSchema ?
Q5SHQ1  (RS14Z_THET8) -  30S ribosomal protein S14 type Z
Seq:
Struc: 		61 a.a.
60 a.a.
Protein chain
Pfam   ArchSchema ?
Q5SJ76  (RS15_THET8) -  30S ribosomal protein S15
Seq:
Struc: 		89 a.a.
88 a.a.
Protein chain
Pfam   ArchSchema ?
Q5SJH3  (RS16_THET8) -  30S ribosomal protein S16
Seq:
Struc: 		88 a.a.
83 a.a.
Protein chain
Pfam   ArchSchema ?
Q5SHP7  (RS17_THET8) -  30S ribosomal protein S17
Seq:
Struc: 		105 a.a.
104 a.a.*
Protein chain
Pfam   ArchSchema ?
Q5SLQ0  (RS18_THET8) -  30S ribosomal protein S18
Seq:
Struc: 		88 a.a.
73 a.a.*
Protein chain
Pfam   ArchSchema ?
Q5SHP2  (RS19_THET8) -  30S ribosomal protein S19
Seq:
Struc: 		93 a.a.
80 a.a.
Protein chain
Pfam   ArchSchema ?
P80380  (RS20_THET8) -  30S ribosomal protein S20
Seq:
Struc: 		106 a.a.
99 a.a.*
Protein chain
Pfam   ArchSchema ?
Q5SIH3  (RSHX_THET8) -  30S ribosomal protein Thx
Seq:
Struc: 		27 a.a.
24 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure
* PDB and UniProt seqs differ at 103 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     intracellular   4 terms 
  Biological process     translation   1 term 
  Biochemical function     structural constituent of ribosome     6 terms  

 

 
    reference    
 
 
DOI no: 10.1016/S0092-8674(01)00435-4 Cell 106:233-241 (2001)
PubMed id: 11511350  
 
 
The path of messenger RNA through the ribosome.
G.Z.Yusupova, M.M.Yusupov, J.H.Cate, H.F.Noller.
 
  ABSTRACT  
 
Using X-ray crystallography, we have directly observed the path of mRNA in the 70S ribosome in Fourier difference maps at 7 A resolution. About 30 nucleotides of the mRNA are wrapped in a groove that encircles the neck of the 30S subunit. The Shine-Dalgarno helix is bound in a large cleft between the head and the back of the platform. At the interface, only about eight nucleotides (-1 to +7), centered on the junction between the A and P codons, are exposed, and bond almost exclusively to 16S rRNA. The mRNA enters the ribosome around position +13 to +15, the location of downstream pseudoknots that stimulate -1 translational frame shifting.
 
  Selected figure(s)  
 
Figure 1.
Figure 1. Nucleotide Sequences of the Three Model mRNAs Used in this StudyThe Shine-Dalgarno sequence (S/D), and P- and A-site codons are underlined. The self-complementary sequences forming the putative A-site helix in MF36 mRNA are overlined 		Figure 2.
Figure 2. Fourier Difference Maps of mRNAs(A) 7 Å Fourier difference map of MK27 mRNA with the mRNA model (yellow) docked, showing the position of the Shine-Dalgarno (S/D) helix (magenta) and the positions of the A- and P-site codons (orange and red, respectively), viewed from the top of the 30S ribosomal subunit.(B) Difference map of the MF36 mRNA, showing a four-base-pair tetraloop helix (A-site helix) fitted to the extra density at the A site.(C) Same as for (B), except that the A-tRNA anticodon stem-loop (green) is shown in the position observed experimentally in the A-tRNA difference map (Yusupov et al., 2001), in place of the A-site mRNA helix. The five-nucleotide (GGAGG/CCUCC) core of the Shine-Dalgarno interaction is shown in magenta, and the rest of the 16S rRNA tail in cyan
 
  The above figures are reprinted by permission from Cell Press: Cell (2001, 106, 233-241) copyright 2001.  
  Figures were selected by the author.  

Literature references that cite this PDB file's key reference

  PubMed id Reference
21539788 C.Y.Liu, M.T.Qureshi, and T.H.Lee (2011).
Interaction Strengths between the Ribosome and tRNA at Various Steps of Translocation.
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mRNA translocation occurs during the second step of ribosomal intersubunit rotation.
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21113134 I.S.Abaeva, A.Marintchev, V.P.Pisareva, C.U.Hellen, and T.V.Pestova (2011).
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21245352 J.Zhu, A.Korostelev, D.A.Costantino, J.P.Donohue, H.F.Noller, and J.S.Kieft (2011).
Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
  Proc Natl Acad Sci U S A, 108, 1839-1844.
PDB codes: 3pyn 3pyo 3pyq 3pyr 3pys 3pyt 3pyu 3pyv
21076851 N.Malys, and J.E.McCarthy (2011).
Translation initiation: variations in the mechanism can be anticipated.
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21448132 V.P.Pisareva, M.A.Skabkin, C.U.Hellen, T.V.Pestova, and A.V.Pisarev (2011).
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Structural motifs of the bacterial ribosomal proteins S20, S18 and S16 that contact rRNA present in the eukaryotic ribosomal proteins S25, S26 and S27A, respectively.
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21109664 A.Ben-Shem, L.Jenner, G.Yusupova, and M.Yusupov (2010).
Crystal structure of the eukaryotic ribosome.
  Science, 330, 1203-1209.
PDB codes: 3o2z 3o30 3o58 3o5h
20852642 C.L.Ng, K.Lang, N.A.Meenan, A.Sharma, A.C.Kelley, C.Kleanthous, and V.Ramakrishnan (2010).
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20235828 J.Frank, and R.L.Gonzalez (2010).
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20360683 J.Wen, and S.Brogna (2010).
Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe.
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20584896 K.E.Berry, S.Waghray, and J.A.Doudna (2010).
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Structural aspects of messenger RNA reading frame maintenance by the ribosome.
  Nat Struct Mol Biol, 17, 555-560.
PDB codes: 3i8f 3i8g 3i8h 3i8i 3i9b 3i9c 3i9d 3i9e
20686685 M.Siwiak, and P.Zielenkiewicz (2010).
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20007152 M.Y.Chou, and K.Y.Chang (2010).
An intermolecular RNA triplex provides insight into structural determinants for the pseudoknot stimulator of -1 ribosomal frameshifting.
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20432247 Z.Meng, N.L.Jackson, O.D.Shcherbakov, H.Choi, and S.W.Blume (2010).
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19095617 A.Devaraj, S.Shoji, E.D.Holbrook, and K.Fredrick (2009).
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19822758 A.Korostelev, M.Laurberg, and H.F.Noller (2009).
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  Cell, 136, 447-460.  
19638248 A.Rich (2009).
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  Q Rev Biophys, 42, 117-137.  
19416977 A.S.Spirin (2009).
The ribosome as a conveying thermal ratchet machine.
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  19539793 C.U.Hellen (2009).
IRES-induced conformational changes in the ribosome and the mechanism of translation initiation by internal ribosomal entry.
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18621088 D.P.Giedroc, and P.V.Cornish (2009).
Frameshifting RNA pseudoknots: structure and mechanism.
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PDB codes: 2rp0 2rp1
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19469554 G.Y.Soung, J.L.Miller, H.Koc, and E.C.Koc (2009).
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19625386 M.H.Mazauric, J.L.Leroy, K.Visscher, S.Yoshizawa, and D.Fourmy (2009).
Footprinting analysis of BWYV pseudoknot-ribosome complexes.
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Interaction of the HIV-1 frameshift signal with the ribosome.
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Non-canonical RNA arrangement in T4-even phages: accommodated ribosome binding site at the gene 26-25 intercistronic junction.
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  19673541 R.J.Marcheschi, K.D.Mouzakis, and S.E.Butcher (2009).
Selection and characterization of small molecules that bind the HIV-1 frameshift site RNA.
  ACS Chem Biol, 4, 844-854.  
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The Crc global regulator binds to an unpaired A-rich motif at the Pseudomonas putida alkS mRNA coding sequence and inhibits translation initiation.
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19779460 S.Chiba, A.Lamsa, and K.Pogliano (2009).
A ribosome-nascent chain sensor of membrane protein biogenesis in Bacillus subtilis.
  EMBO J, 28, 3461-3475.  
19129224 T.Dale, R.P.Fahlman, M.Olejniczak, and O.C.Uhlenbeck (2009).
Specificity of the ribosomal A site for aminoacyl-tRNAs.
  Nucleic Acids Res, 37, 1202-1210.  
20025795 X.Agirrezabala, and J.Frank (2009).
Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu.
  Q Rev Biophys, 42, 159-200.  
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Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.
  Nucleic Acids Res, 37, 5167-5182.  
18369869 A.Görg, C.Lück, and W.Weiss (2008).
Sample prefractionation in granulated sephadex IEF gels.
  Methods Mol Biol, 424, 277-286.  
18758445 A.Simonetti, S.Marzi, A.G.Myasnikov, A.Fabbretti, M.Yusupov, C.O.Gualerzi, and B.P.Klaholz (2008).
Structure of the 30S translation initiation complex.
  Nature, 455, 416-420.  
18464793 A.V.Pisarev, V.G.Kolupaeva, M.M.Yusupov, C.U.Hellen, and T.V.Pestova (2008).
Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes.
  EMBO J, 27, 1609-1621.  
18367719 D.Dulude, G.Théberge-Julien, L.Brakier-Gingras, and N.Heveker (2008).
Selection of peptides interfering with a ribosomal frameshift in the human immunodeficiency virus type 1.
  RNA, 14, 981-991.  
18544041 E.M.Youngman, M.E.McDonald, and R.Green (2008).
Peptide release on the ribosome: mechanism and implications for translational control.
  Annu Rev Microbiol, 62, 353-373.  
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Step-wise formation of eukaryotic double-row polyribosomes and circular translation of polysomal mRNA.
  Nucleic Acids Res, 36, 2476-2488.  
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  Genes Dev, 22, 2242-2255.  
18755843 J.E.Brock, S.Pourshahian, J.Giliberti, P.A.Limbach, and G.R.Janssen (2008).
Ribosomes bind leaderless mRNA in Escherichia coli through recognition of their 5'-terminal AUG.
  RNA, 14, 2159-2169.  
19111653 J.Richards, and J.G.Belasco (2008).
A new window onto translational repression by bacterial sRNAs.
  Mol Cell, 32, 751-753.  
18637734 K.Bakowska-Zywicka, A.M.Kietrys, and T.Twardowski (2008).
Antisense oligonucleotides targeting universally conserved 26S rRNA domains of plant ribosomes at different steps of polypeptide elongation.
  Oligonucleotides, 18, 175-186.  
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[The environment of tRNA 3'-terminus in 80S ribosome A and P sites].
  Bioorg Khim, 34, 96.  
18522973 L.M.Chubiz, and C.V.Rao (2008).
Computational design of orthogonal ribosomes.
  Nucleic Acids Res, 36, 4038-4046.  
19111662 M.Bouvier, C.M.Sharma, F.Mika, K.H.Nierhaus, and J.Vogel (2008).
Small RNA binding to 5' mRNA coding region inhibits translational initiation.
  Mol Cell, 32, 827-837.  
18497739 M.Y.Pavlov, A.Antoun, M.Lovmar, and M.Ehrenberg (2008).
Complementary roles of initiation factor 1 and ribosome recycling factor in 70S ribosome splitting.
  EMBO J, 27, 1706-1717.  
18772887 N.M.Wills, M.O'Connor, C.C.Nelson, C.C.Rettberg, W.M.Huang, R.F.Gesteland, and J.F.Atkins (2008).
Translational bypassing without peptidyl-tRNA anticodon scanning of coding gap mRNA.
  EMBO J, 27, 2533-2544.  
19029596 O.Kurkcuoglu, P.Doruker, T.Z.Sen, A.Kloczkowski, and R.L.Jernigan (2008).
The ribosome structure controls and directs mRNA entry, translocation and exit dynamics.
  Phys Biol, 5, 046005.  
18400176 P.Chandramouli, M.Topf, J.F.Ménétret, N.Eswar, J.J.Cannone, R.R.Gutell, A.Sali, and C.W.Akey (2008).
Structure of the mammalian 80S ribosome at 8.7 A resolution.
  Structure, 16, 535-548.
PDB codes: 2zkq 2zkr
18367782 S.Cao, and S.J.Chen (2008).
Predicting ribosomal frameshifting efficiency.
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18953726 S.Marzi, P.Fechter, C.Chevalier, P.Romby, and T.Geissmann (2008).
RNA switches regulate initiation of translation in bacteria.
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18647167 S.Yao, J.B.Blaustein, and D.H.Bechhofer (2008).
Erythromycin-induced ribosome stalling and RNase J1-mediated mRNA processing in Bacillus subtilis.
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18299414 Y.H.Min, A.R.Kwon, E.J.Yoon, M.J.Shim, and E.C.Choi (2008).
Translational attenuation and mRNA stabilization as mechanisms of erm(B) induction by erythromycin.
  Antimicrob Agents Chemother, 52, 1782-1789.  
19088750 Y.S.Khairulina, M.V.Molotkov, K.N.Bulygin, D.M.Graifer, A.G.Ven'yaminova, L.Y.Frolova, J.Stahl, and G.G.Karpova (2008).
[Protein S3 Fragments Neighboring mRNA during Elongation and Translation Termination on the Human Ribosome.]
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17612493 A.Grimson, K.K.Farh, W.K.Johnston, P.Garrett-Engele, L.P.Lim, and D.P.Bartel (2007).
MicroRNA targeting specificity in mammals: determinants beyond seed pairing.
  Mol Cell, 27, 91.  
17764954 A.Korostelev, and H.F.Noller (2007).
The ribosome in focus: new structures bring new insights.
  Trends Biochem Sci, 32, 434-441.  
17940016 A.Korostelev, S.Trakhanov, H.Asahara, M.Laurberg, L.Lancaster, and H.F.Noller (2007).
Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome.
  Proc Natl Acad Sci U S A, 104, 16840-16843.
PDB codes: 1vsp 2qnh
17683199 A.L.Manuell, J.Quispe, and S.P.Mayfield (2007).
Structure of the chloroplast ribosome: novel domains for translation regulation.
  PLoS Biol, 5, e209.  
17881742 C.Guarraia, L.Norris, A.Raman, and P.J.Farabaugh (2007).
Saturation mutagenesis of a +1 programmed frameshift-inducing mRNA sequence derived from a yeast retrotransposon.
  RNA, 13, 1940-1947.  
17660276 C.L.Sanders, and J.F.Curran (2007).
Genetic analysis of the E site during RF2 programmed frameshifting.
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17128284 C.S.Fraser, and J.A.Doudna (2007).
Structural and mechanistic insights into hepatitis C viral translation initiation.
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17317625 D.Pan, S.V.Kirillov, and B.S.Cooperman (2007).
Kinetically competent intermediates in the translocation step of protein synthesis.
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17283215 D.Piekna-Przybylska, W.A.Decatur, and M.J.Fournier (2007).
New bioinformatic tools for analysis of nucleotide modifications in eukaryotic rRNA.
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17329356 D.Taliaferro, and P.J.Farabaugh (2007).
An mRNA sequence derived from the yeast EST3 gene stimulates programmed +1 translational frameshifting.
  RNA, 13, 606-613.  
17169991 H.R.Jonker, S.Ilin, S.K.Grimm, J.Wöhnert, and H.Schwalbe (2007).
L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy.
  Nucleic Acids Res, 35, 441-454.
PDB codes: 2jq7 2nyo
17632571 I.Brierley, S.Pennell, and R.J.Gilbert (2007).
Viral RNA pseudoknots: versatile motifs in gene expression and replication.
  Nat Rev Microbiol, 5, 598-610.  
17085569 J.E.Brock, R.L.Paz, P.Cottle, and G.R.Janssen (2007).
Naturally occurring adenines within mRNA coding sequences affect ribosome binding and expression in Escherichia coli.
  J Bacteriol, 189, 501-510.  
17434125 L.A.Passmore, T.M.Schmeing, D.Maag, D.J.Applefield, M.G.Acker, M.A.Algire, J.R.Lorsch, and V.Ramakrishnan (2007).
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome.
  Mol Cell, 26, 41-50.  
17721443 L.Jenner, B.Rees, M.Yusupov, and G.Yusupova (2007).
Messenger RNA conformations in the ribosomal E site revealed by X-ray crystallography.
  EMBO Rep, 8, 846-850.  
17711575 L.Pnueli, and Y.Arava (2007).
Genome-wide polysomal analysis of a yeast strain with mutated ribosomal protein S9.
  BMC Genomics, 8, 285.  
18042701 M.R.Sharma, D.N.Wilson, P.P.Datta, C.Barat, F.Schluenzen, P.Fucini, and R.K.Agrawal (2007).
Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins.
  Proc Natl Acad Sci U S A, 104, 19315-19320.
PDB codes: 3bbn 3bbo
17704818 M.Schubert, K.Lapouge, O.Duss, F.C.Oberstrass, I.Jelesarov, D.Haas, and F.H.Allain (2007).
Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA.
  Nat Struct Mol Biol, 14, 807-813.
PDB code: 2jpp
17886434 M.V.Molotkov, D.M.Graĭfer, E.A.Popugaeva, K.N.Bulygin, M.I.Meshchaninova, A.G.Ven'iaminova, and G.G.Karpova (2007).
[Protein S3 in the human 80S ribosome adjoins mRNA from 3'-side of the A-site codon]
  Bioorg Khim, 33, 431-441.  
17937620 N.Fischer, A.Paleskava, K.B.Gromadski, A.L.Konevega, M.C.Wahl, H.Stark, and M.V.Rodnina (2007).
Towards understanding selenocysteine incorporation into bacterial proteins.
  Biol Chem, 388, 1061-1067.  
17996707 P.P.Datta, D.N.Wilson, M.Kawazoe, N.K.Swami, T.Kaminishi, M.R.Sharma, T.M.Booth, C.Takemoto, P.Fucini, S.Yokoyama, and R.K.Agrawal (2007).
Structural aspects of RbfA action during small ribosomal subunit assembly.
  Mol Cell, 28, 434-445.
PDB codes: 2dyj 2r1c 2r1g
17868691 R.J.Marcheschi, D.W.Staple, and S.E.Butcher (2007).
Programmed ribosomal frameshifting in SIV is induced by a highly structured RNA stem-loop.
  J Mol Biol, 373, 652-663.
PDB code: 2jtp
17291191 S.D.Moore, and R.T.Sauer (2007).
The tmRNA system for translational surveillance and ribosome rescue.
  Annu Rev Biochem, 76, 101-124.  
17889647 S.Marzi, A.G.Myasnikov, A.Serganov, C.Ehresmann, P.Romby, M.Yusupov, and B.P.Klaholz (2007).
Structured mRNAs regulate translation initiation by binding to the platform of the ribosome.
  Cell, 130, 1019-1031.
PDB code: 2vaz
17377584 S.Uemura, M.Dorywalska, T.H.Lee, H.D.Kim, J.D.Puglisi, and S.Chu (2007).
Peptide bond formation destabilizes Shine-Dalgarno interaction on the ribosome.
  Nature, 446, 454-457.  
17355865 T.Kaminishi, D.N.Wilson, C.Takemoto, J.M.Harms, M.Kawazoe, F.Schluenzen, K.Hanawa-Suetsugu, M.Shirouzu, P.Fucini, and S.Yokoyama (2007).
A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction.
  Structure, 15, 289-297.
PDB code: 2e5l
16962654 A.Korostelev, S.Trakhanov, M.Laurberg, and H.F.Noller (2006).
Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements.
  Cell, 126, 1065-1077.
PDB codes: 1vsa 2ow8
16682566 A.Raman, C.Guarraia, D.Taliaferro, G.Stahl, and P.J.Farabaugh (2006).
An mRNA sequence derived from a programmed frameshifting signal decreases codon discrimination during translation initiation.
  RNA, 12, 1154-1160.  
16510876 A.V.Pisarev, V.G.Kolupaeva, V.P.Pisareva, W.C.Merrick, C.U.Hellen, and T.V.Pestova (2006).
Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex.
  Genes Dev, 20, 624-636.  
16452425 A.Wietzorrek, H.Schwarz, C.Herrmann, and V.Braun (2006).
The genome of the novel phage Rtp, with a rosette-like tail tip, is homologous to the genome of phage T1.
  J Bacteriol, 188, 1419-1436.  
16998486 B.S.Schuwirth, J.M.Day, C.W.Hau, G.R.Janssen, A.E.Dahlberg, J.H.Cate, and A.Vila-Sanjurjo (2006).
Structural analysis of kasugamycin inhibition of translation.
  Nat Struct Mol Biol, 13, 879-886.
PDB codes: 1vs5 1vs6 1vs7 1vs8
16920740 C.M.Henderson, C.B.Anderson, and M.T.Howard (2006).
Antisense-induced ribosomal frameshifting.
  Nucleic Acids Res, 34, 4302-4310.  
16581790 D.E.Andreev, I.M.Terenin, Y.E.Dunaevsky, S.E.Dmitriev, and I.N.Shatsky (2006).
A leaderless mRNA can bind to mammalian 80S ribosomes and direct polypeptide synthesis in the absence of translation initiation factors.
  Mol Cell Biol, 26, 3164-3169.  
16307820 E.Jan (2006).
Divergent IRES elements in invertebrates.
  Virus Res, 119, 16-28.  
16808174 E.S.Laletina, D.M.Graĭfer, A.A.Malygin, I.N.Shatskiĭ, and G.G.Karpova (2006).
[Molecular environment of the subdomain IIIe loop of the RNA IRES element of hepatitis C virus on the human 40S ribosomal subunit]
  Bioorg Khim, 32, 311-319.  
16680139 F.J.Isaacs, D.J.Dwyer, and J.J.Collins (2006).
RNA synthetic biology.
  Nat Biotechnol, 24, 545-554.  
16487710 G.Hirokawa, N.Demeshkina, N.Iwakura, H.Kaji, and A.Kaji (2006).
The ribosome-recycling step: consensus or controversy?
  Trends Biochem Sci, 31, 143-149.  
17051149 G.Yusupova, L.Jenner, B.Rees, D.Moras, and M.Yusupov (2006).
Structural basis for messenger RNA movement on the ribosome.
  Nature, 444, 391-394.
PDB codes: