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PDBsum entry 1if5

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protein ligands metals links
Lyase PDB id
1if5
Jmol
Contents
Protein chain
258 a.a. *
Ligands
FBT
Metals
_ZN
_HG
Waters ×89
* Residue conservation analysis
PDB id:
1if5
Name: Lyase
Title: Carbonic anhydrase ii complexed with 2,6- difluorobenzenesulfonamide
Structure: Carbonic anhydrase ii. Chain: a. Synonym: carbonate dehydratase ii. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.00Å     R-factor:   0.221     R-free:   0.287
Authors: C.-Y.Kim,D.W.Christianson
Key ref: C.-Y.Kim and d.w.christianson Binding of fluorine substituted benzenesulfonamides to carbonic anhydrase ii. To be published, .
Date:
12-Apr-01     Release date:   02-May-01    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2
Seq:
Struc:
260 a.a.
258 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.1  - Carbonate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: H2CO3 = CO2 + H2O
H(2)CO(3)
= CO(2)
+ H(2)O
      Cofactor: Zn(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular space   11 terms 
  Biological process     angiotensin-mediated signaling pathway   22 terms 
  Biochemical function     protein binding     5 terms