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PDBsum entry 1hca

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protein metals links
Lyase(oxo-acid) PDB id
1hca
Jmol
Contents
Protein chain
255 a.a. *
Metals
_HG
_ZN
Waters ×68
* Residue conservation analysis
PDB id:
1hca
Name: Lyase(oxo-acid)
Title: Unexpected ph-dependent conformation of his-64, the proton shuttle of carbonic anhydrase ii.
Structure: Carbonic anhydrase ii. Chain: a. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606
Resolution:
2.30Å     R-factor:   0.164    
Authors: S.K.Nair,D.W.Christianson
Key ref: S.K.Nair and d.w.christianson (1991). Unexpected ph-Dependent conformation of his-64, The proton shuttle of carbonic anhydrase ii.. J.Am.Chem.Soc., 113, 9455.
Date:
02-Apr-92     Release date:   15-Oct-92    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2
Seq:
Struc:
260 a.a.
255 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.1  - Carbonate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: H2CO3 = CO2 + H2O
H(2)CO(3)
= CO(2)
+ H(2)O
      Cofactor: Zn(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular space   11 terms 
  Biological process     angiotensin-mediated signaling pathway   21 terms 
  Biochemical function     protein binding     5 terms