PDBsum entry: 1gtw

Transcription/DNA

PDB id: 1gtw

Contents

Protein chains

66 a.a. *

DNA/RNA

Waters ×316

* Residue conservation analysis

PDB id:

1gtw

Name:

Transcription/DNA

Title:

Crystal structure of c/ebpbeta bzip dimeric bound to a DNA fragment from the tom-1a promoter

Structure:

Caat/enhancer binding protein beta. Chain: a, b. Fragment: bzip domain, residues 259-336. Synonym: c/ebp beta, nuclear factor nf-il6, transcription factor 5. Engineered: yes. 5'-d( Ap Ap Tp Gp Tp Gp Gp Cp Gp Cp Ap Ap Tp Cp Cp T)-3'. Chain: c.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic: yes

Biol. unit:

Octamer (from PDB file)

Resolution:

1.85Å R-factor: 0.231 R-free: 0.271

Authors:

T.H.Tahirov,K.Ogata

Key ref:

T.H.Tahirov et al. Structural basis for flexible base recognition by c/ebpbeta. To be published,

Date:

22-Jan-02 Release date: 06-Feb-04

Protein chains

P17676  (CEBPB_HUMAN) -  CCAAT/enhancer-binding protein beta

Seq: 345 a.a.

Struc: 66 a.a.

 Gene Ontology (GO) functional annotation 

• Cellular component: nucleus (1 term)
• Biological process: regulation of transcription, DNA-dependent (1 term)
• Biochemical function: transcription factor activity (3 terms)