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PDBsum entry 1fc1
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Immunoglobulin
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PDB id
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1fc1
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Contents |
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* Residue conservation analysis
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DOI no:
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Biochemistry
20:2361-2370
(1981)
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PubMed id:
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Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.
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J.Deisenhofer.
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ABSTRACT
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The model of human Fc fragment was refined at 2.9-A resolution. Two different
automated procedures for crystallographic refinement were used [Deisenhofer, J.,
& Steigemann, W. (1975) Acta Crystallogr., Sec. B B31, 238; Jack, A., &
Levitt, M. (1978) Acta Crystallogr., Sect. A A34, 931]. The final R value is
0.22. The dimer of CH3 domains closely resembles the CH1-CL aggregate in Fab
fragments. There is no contact between CH2 domains. The contact between CH2 and
CH3 domains has about one-third of the size of the CH3-CH3 contact. The
carbohydrate, a branched chain of nine hexose units, covers parts of the
C-contact face of the CH2 domain, shielding hydrophobic residues on this
surface. Six atoms of the carbohydrate are within hydrogen-bonding distance of
atoms in the CH2 domain. Crystallographic refinement of the complex between Fc
fragment and fragment B of protein A from Staphylococcus aureus reduced the R
value of the model is 0.24. A major part of the structure of fragment B consists
of two alpha helics; the rest of the polypeptide chain is folded irregularly. In
the crystal, fragment B forms two contacts with Fc fragment molecules. Contact 1
involves residues from both helices of fragment B, and residues from the CH2 and
CH3 domains of FC, and is predominantly hydrophobic. Contact 2 is smaller than
contact 1. Residues from the second helix and adjacent residues of fragment B
and residues only from the CH3 domain of Fc contribute to contact 2. The nature
of contact 2 is mainly polar and includes a sulfate ion. There are strong
arguments that contact 1 is the fragment B-Fc contact formed in solution under
physiological conditions, while contact 2 is a crystal contact.
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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A.P.Le Brun,
S.A.Holt,
D.S.Shah,
C.F.Majkrzak,
and
J.H.Lakey
(2011).
The structural orientation of antibody layers bound to engineered biosensor surfaces.
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Biomaterials,
32,
3303-3311.
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A.W.Barb,
and
J.H.Prestegard
(2011).
NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic.
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Nat Chem Biol,
7,
147-153.
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E.V.Sidorin,
and
T.F.Solov'eva
(2011).
IgG-Binding Proteins of Bacteria.
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Biochemistry (Mosc),
76,
295-308.
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N.Chennamsetty,
V.Voynov,
V.Kayser,
B.Helk,
and
B.L.Trout
(2011).
Prediction of protein binding regions.
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Proteins,
79,
888-897.
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P.Järver,
C.Mikaelsson,
and
A.E.Karlström
(2011).
Chemical synthesis and evaluation of a backbone-cyclized minimized 2-helix Z-domain.
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J Pept Sci,
17,
463-469.
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S.Amani,
and
A.Naeem
(2011).
Acetonitrile can promote formation of different structural intermediate states on aggregation pathway of immunoglobulin G from human and bovine.
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Int J Biol Macromol,
49,
71-78.
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A.Ercan,
J.Cui,
D.E.Chatterton,
K.D.Deane,
M.M.Hazen,
W.Brintnell,
C.I.O'Donnell,
L.A.Derber,
M.E.Weinblatt,
N.A.Shadick,
D.A.Bell,
E.Cairns,
D.H.Solomon,
V.M.Holers,
P.M.Rudd,
and
D.M.Lee
(2010).
Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis.
|
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Arthritis Rheum,
62,
2239-2248.
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D.Amorós,
A.Ortega,
S.E.Harding,
and
J.García de la Torre
(2010).
Multi-scale calculation and global-fit analysis of hydrodynamic properties of biological macromolecules: determination of the overall conformation of antibody IgG molecules.
|
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Eur Biophys J,
39,
361-370.
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F.Liu,
M.Dubey,
H.Takahashi,
D.G.Castner,
and
D.W.Grainger
(2010).
Immobilized antibody orientation analysis using secondary ion mass spectrometry and fluorescence imaging of affinity-generated patterns.
|
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Anal Chem,
82,
2947-2958.
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H.K.Kim,
A.G.Cheng,
H.Y.Kim,
D.M.Missiakas,
and
O.Schneewind
(2010).
Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice.
|
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J Exp Med,
207,
1863-1870.
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H.M.Nguyen,
M.A.Rocha,
K.R.Chintalacharuvu,
and
D.O.Beenhouwer
(2010).
Detection and quantification of Panton-Valentine leukocidin in Staphylococcus aureus cultures by ELISA and Western blotting: diethylpyrocarbonate inhibits binding of protein A to IgG.
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J Immunol Methods,
356,
1-5.
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J.H.Davis,
C.Aperlo,
Y.Li,
E.Kurosawa,
Y.Lan,
K.M.Lo,
and
J.S.Huston
(2010).
SEEDbodies: fusion proteins based on strand-exchange engineered domain (SEED) CH3 heterodimers in an Fc analogue platform for asymmetric binders or immunofusions and bispecific antibodies.
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Protein Eng Des Sel,
23,
195-202.
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W.Burkitt,
P.Domann,
and
G.O'Connor
(2010).
Conformational changes in oxidatively stressed monoclonal antibodies studied by hydrogen exchange mass spectrometry.
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Protein Sci,
19,
826-835.
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Y.Nomura,
S.Sugiyama,
T.Sakamoto,
S.Miyakawa,
H.Adachi,
K.Takano,
S.Murakami,
T.Inoue,
Y.Mori,
Y.Nakamura,
and
H.Matsumura
(2010).
Conformational plasticity of RNA for target recognition as revealed by the 2.15 A crystal structure of a human IgG-aptamer complex.
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Nucleic Acids Res,
38,
7822-7829.
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PDB code:
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A.Bonner,
A.Almogren,
P.B.Furtado,
M.A.Kerr,
and
S.J.Perkins
(2009).
Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.
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Mucosal Immunol,
2,
74-84.
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PDB code:
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B.A.Wurzburg,
and
T.S.Jardetzky
(2009).
Conformational flexibility in immunoglobulin E-Fc 3-4 revealed in multiple crystal forms.
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J Mol Biol,
393,
176-190.
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PDB codes:
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H.Liu,
G.Gaza-Bulseco,
and
L.Zhou
(2009).
Mass spectrometry analysis of photo-induced methionine oxidation of a recombinant human monoclonal antibody.
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J Am Soc Mass Spectrom,
20,
525-528.
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H.Pan,
K.Chen,
L.Chu,
F.Kinderman,
I.Apostol,
and
G.Huang
(2009).
Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn.
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Protein Sci,
18,
424-433.
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I.Perdivara,
L.J.Deterding,
C.Cozma,
K.B.Tomer,
and
M.Przybylski
(2009).
Glycosylation profiles of epitope-specific anti-beta-amyloid antibodies revealed by liquid chromatography-mass spectrometry.
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Glycobiology,
19,
958-970.
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J.E.Butler,
N.Wertz,
N.Deschacht,
and
I.Kacskovics
(2009).
Porcine IgG: structure, genetics, and evolution.
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Immunogenetics,
61,
209-230.
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J.S.Park,
M.K.Cho,
E.J.Lee,
K.Y.Ahn,
K.E.Lee,
J.H.Jung,
Y.Cho,
S.S.Han,
Y.K.Kim,
and
J.Lee
(2009).
A highly sensitive and selective diagnostic assay based on virus nanoparticles.
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Nat Nanotechnol,
4,
259-264.
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L.Holm,
P.Moody,
and
M.Howarth
(2009).
Electrophilic affibodies forming covalent bonds to protein targets.
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J Biol Chem,
284,
32906-32913.
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M.Allhorn,
and
M.Collin
(2009).
Sugar-free antibodies--the bacterial solution to autoimmunity?
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Ann N Y Acad Sci,
1173,
664-669.
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P.Gagnon,
C.W.Cheung,
and
P.J.Yazaki
(2009).
Cooperative multimodal retention of IgG, fragments, and aggregates on hydroxyapatite.
|
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J Sep Sci,
32,
3857-3865.
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P.Speziale,
G.Pietrocola,
S.Rindi,
M.Provenzano,
G.Provenza,
A.Di Poto,
L.Visai,
and
C.R.Arciola
(2009).
Structural and functional role of Staphylococcus aureus surface components recognizing adhesive matrix molecules of the host.
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Future Microbiol,
4,
1337-1352.
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R.Jefferis
(2009).
Glycosylation as a strategy to improve antibody-based therapeutics.
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Nat Rev Drug Discov,
8,
226-234.
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R.Jefferis
(2009).
Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action.
|
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Trends Pharmacol Sci,
30,
356-362.
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R.P.Bahadur,
and
P.Chakrabarti
(2009).
Discriminating the native structure from decoys using scoring functions based on the residue packing in globular proteins.
|
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BMC Struct Biol,
9,
76.
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S.Bonetto,
L.Spadola,
A.G.Buchanan,
L.Jermutus,
and
J.Lund
(2009).
Identification of cyclic peptides able to mimic the functional epitope of IgG1-Fc for human Fc gammaRI.
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FASEB J,
23,
575-585.
|
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V.Voynov,
N.Chennamsetty,
V.Kayser,
B.Helk,
K.Forrer,
H.Zhang,
C.Fritsch,
H.Heine,
and
B.L.Trout
(2009).
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
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PLoS One,
4,
e8425.
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X.Z.Wu,
S.Asai,
and
Y.Yamaguchi
(2009).
Study of protein-protein binding reaction by whole-column fluorescence-imaged CIEF.
|
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Electrophoresis,
30,
1552-1557.
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Y.Yang,
Y.Zhu,
Q.Chen,
Y.Liu,
Y.Zeng,
and
F.Xu
(2009).
Carbon-nanotube-activated Pt quartz-crystal microbalance for the immunoassay of human IgG.
|
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Small,
5,
351-355.
|
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A.I.Taylor,
H.J.Gould,
B.J.Sutton,
and
R.A.Calvert
(2008).
Avian IgY binds to a monocyte receptor with IgG-like kinetics despite an IgE-like structure.
|
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J Biol Chem,
283,
16384-16390.
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A.McAuley,
J.Jacob,
C.G.Kolvenbach,
K.Westland,
H.J.Lee,
S.R.Brych,
D.Rehder,
G.R.Kleemann,
D.N.Brems,
and
M.Matsumura
(2008).
Contributions of a disulfide bond to the structure, stability, and dimerization of human IgG1 antibody CH3 domain.
|
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Protein Sci,
17,
95.
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A.P.Le Brun,
S.A.Holt,
D.S.Shah,
C.F.Majkrzak,
and
J.H.Lakey
(2008).
Monitoring the assembly of antibody-binding membrane protein arrays using polarised neutron reflection.
|
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Eur Biophys J,
37,
639-645.
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E.D.Nelson,
and
N.V.Grishin
(2008).
Folding domain B of protein A on a dynamically partitioned free energy landscape.
|
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Proc Natl Acad Sci U S A,
105,
1489-1493.
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E.R.Sprague,
H.Reinhard,
E.J.Cheung,
A.H.Farley,
R.D.Trujillo,
H.Hengel,
and
P.J.Bjorkman
(2008).
The human cytomegalovirus Fc receptor gp68 binds the Fc CH2-CH3 interface of immunoglobulin G.
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J Virol,
82,
3490-3499.
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F.Nimmerjahn,
and
J.V.Ravetch
(2008).
Fcgamma receptors as regulators of immune responses.
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Nat Rev Immunol,
8,
34-47.
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G.W.Platt,
K.E.Routledge,
S.W.Homans,
and
S.E.Radford
(2008).
Fibril growth kinetics reveal a region of beta2-microglobulin important for nucleation and elongation of aggregation.
|
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J Mol Biol,
378,
251-263.
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H.Lei,
C.Wu,
Z.X.Wang,
Y.Zhou,
and
Y.Duan
(2008).
Folding processes of the B domain of protein A to the native state observed in all-atom ab initio folding simulations.
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J Chem Phys,
128,
235105.
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H.Liu,
G.Gaza-Bulseco,
D.Faldu,
C.Chumsae,
and
J.Sun
(2008).
Heterogeneity of monoclonal antibodies.
|
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J Pharm Sci,
97,
2426-2447.
|
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J.N.Arnold,
R.Saldova,
U.M.Hamid,
and
P.M.Rudd
(2008).
Evaluation of the serum N-linked glycome for the diagnosis of cancer and chronic inflammation.
|
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Proteomics,
8,
3284-3293.
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L.G.Sparrow,
M.C.Lawrence,
J.J.Gorman,
P.M.Strike,
C.P.Robinson,
N.M.McKern,
and
C.W.Ward
(2008).
N-linked glycans of the human insulin receptor and their distribution over the crystal structure.
|
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Proteins,
71,
426-439.
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M.Collin,
O.Shannon,
and
L.Björck
(2008).
IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.
|
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Proc Natl Acad Sci U S A,
105,
4265-4270.
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M.J.Lewis,
B.Wagner,
and
J.M.Woof
(2008).
The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies.
|
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Mol Immunol,
45,
818-827.
|
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M.J.Lewis,
M.Meehan,
P.Owen,
and
J.M.Woof
(2008).
A common theme in interaction of bacterial immunoglobulin-binding proteins with immunoglobulins illustrated in the equine system.
|
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J Biol Chem,
283,
17615-17623.
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P.A.Nygren
(2008).
Alternative binding proteins: affibody binding proteins developed from a small three-helix bundle scaffold.
|
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FEBS J,
275,
2668-2676.
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R.J.Gordon,
and
F.D.Lowy
(2008).
Pathogenesis of methicillin-resistant Staphylococcus aureus infection.
|
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Clin Infect Dis,
46,
S350-S359.
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S.Kashanian,
S.Ghobadi,
K.Omidfar,
and
H.Ravan
(2008).
Structural and functional study of mouse antidigoxin monoclonal antibody against thermal variation.
|
| |
Hybridoma (Larchmt),
27,
123-130.
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S.Miyakawa,
Y.Nomura,
T.Sakamoto,
Y.Yamaguchi,
K.Kato,
S.Yamazaki,
and
Y.Nakamura
(2008).
Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G.
|
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RNA,
14,
1154-1163.
|
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S.Sugiyama,
Y.Nomura,
T.Sakamoto,
T.Kitatani,
A.Kobayashi,
S.Miyakawa,
Y.Takahashi,
H.Adachi,
K.Takano,
S.Murakami,
T.Inoue,
Y.Mori,
Y.Nakamura,
and
H.Matsumura
(2008).
Crystallization and preliminary X-ray diffraction studies of an RNA aptamer in complex with the human IgG Fc fragment.
|
| |
Acta Crystallogr Sect F Struct Biol Cryst Commun,
64,
942-944.
|
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S.Y.Wang,
and
G.Weiner
(2008).
Complement and cellular cytotoxicity in antibody therapy of cancer.
|
| |
Expert Opin Biol Ther,
8,
759-768.
|
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T.S.Raju
(2008).
Terminal sugars of Fc glycans influence antibody effector functions of IgGs.
|
| |
Curr Opin Immunol,
20,
471-478.
|
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V.Oganesyan,
C.Gao,
L.Shirinian,
H.Wu,
and
W.F.Dall'Acqua
(2008).
Structural characterization of a human Fc fragment engineered for lack of effector functions.
|
| |
Acta Crystallogr D Biol Crystallogr,
64,
700-704.
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PDB code:
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W.Hoyer,
C.Grönwall,
A.Jonsson,
S.Ståhl,
and
T.Härd
(2008).
Stabilization of a beta-hairpin in monomeric Alzheimer's amyloid-beta peptide inhibits amyloid formation.
|
| |
Proc Natl Acad Sci U S A,
105,
5099-5104.
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PDB code:
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A.M.Namboodiri,
A.Budkowska,
P.J.Nietert,
and
J.P.Pandey
(2007).
Fc gamma receptor-like hepatitis C virus core protein binds differentially to IgG of discordant Fc (GM) genotypes.
|
| |
Mol Immunol,
44,
3805-3808.
|
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A.Zavialov,
G.Zav'yalova,
T.Korpela,
and
V.Zav'yalov
(2007).
FGL chaperone-assembled fimbrial polyadhesins: anti-immune armament of Gram-negative bacterial pathogens.
|
| |
FEMS Microbiol Rev,
31,
478-514.
|
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C.Mersich,
W.Billes,
and
A.Jungbauer
(2007).
Identification of a ligand for IgG-Fc derived from a soluble peptide library based on fusion proteins secreted by S. cerevisiae.
|
| |
Biotechnol J,
2,
672-677.
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D.C.Roopenian,
and
S.Akilesh
(2007).
FcRn: the neonatal Fc receptor comes of age.
|
| |
Nat Rev Immunol,
7,
715-725.
|
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F.A.Majid,
M.Butler,
and
M.Al-Rubeai
(2007).
Glycosylation of an immunoglobulin produced from a murine hybridoma cell line: the effect of culture mode and the anti-apoptotic gene, bcl-2.
|
| |
Biotechnol Bioeng,
97,
156-169.
|
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F.Nimmerjahn,
R.M.Anthony,
and
J.V.Ravetch
(2007).
Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity.
|
| |
Proc Natl Acad Sci U S A,
104,
8433-8437.
|
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H.Mitomo,
H.Shigematsu,
E.Kobatake,
H.Furusawa,
and
Y.Okahata
(2007).
IgG binding kinetics to oligo B protein A domains on lipid layers immobilized on a 27 MHz quartz-crystal microbalance.
|
| |
J Mol Recognit,
20,
83-89.
|
|
|
|
|
|
|
H.Ogi,
K.Motohisa,
K.Hatanaka,
T.Ohmori,
M.Hirao,
and
M.Nishiyama
(2007).
Concentration dependence of IgG-protein A affinity studied by wireless-electrodeless QCM.
|
| |
Biosens Bioelectron,
22,
3238-3242.
|
|
|
|
|
|
|
H.S.Lee,
J.Choi,
and
S.Yoon
(2007).
QHELIX: a computational tool for the improved measurement of inter-helical angles in proteins.
|
| |
Protein J,
26,
556-561.
|
|
|
|
|
|
|
J.Bubeck Wardenburg,
R.J.Patel,
and
O.Schneewind
(2007).
Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia.
|
| |
Infect Immun,
75,
1040-1044.
|
|
|
|
|
|
|
J.N.Arnold,
M.R.Wormald,
R.B.Sim,
P.M.Rudd,
and
R.A.Dwek
(2007).
The impact of glycosylation on the biological function and structure of human immunoglobulins.
|
| |
Annu Rev Immunol,
25,
21-50.
|
|
|
|
|
|
|
K.S.Nandakumar,
M.Collin,
A.Olsén,
F.Nimmerjahn,
A.M.Blom,
J.V.Ravetch,
and
R.Holmdahl
(2007).
Endoglycosidase treatment abrogates IgG arthritogenicity: importance of IgG glycosylation in arthritis.
|
| |
Eur J Immunol,
37,
2973-2982.
|
|
|
|
|
|
|
L.C.James,
A.H.Keeble,
Z.Khan,
D.A.Rhodes,
and
J.Trowsdale
(2007).
Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function.
|
| |
Proc Natl Acad Sci U S A,
104,
6200-6205.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
P.A.Ramsland,
N.Willoughby,
H.M.Trist,
W.Farrugia,
P.M.Hogarth,
J.D.Fraser,
and
B.D.Wines
(2007).
Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1.
|
| |
Proc Natl Acad Sci U S A,
104,
15051-15056.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
R.Jefferis
(2007).
Antibody therapeutics: isotype and glycoform selection.
|
| |
Expert Opin Biol Ther,
7,
1401-1413.
|
|
|
|
|
|
|
B.D.Wines,
N.Willoughby,
J.D.Fraser,
and
P.M.Hogarth
(2006).
A competitive mechanism for staphylococcal toxin SSL7 inhibiting the leukocyte IgA receptor, Fc alphaRI, is revealed by SSL7 binding at the C alpha2/C alpha3 interface of IgA.
|
| |
J Biol Chem,
281,
1389-1393.
|
|
|
|
|
|
|
C.Vaccaro,
R.Bawdon,
S.Wanjie,
R.J.Ober,
and
E.S.Ward
(2006).
Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies.
|
| |
Proc Natl Acad Sci U S A,
103,
18709-18714.
|
|
|
|
|
|
|
E.R.Sprague,
C.Wang,
D.Baker,
and
P.J.Bjorkman
(2006).
Crystal structure of the HSV-1 Fc receptor bound to Fc reveals a mechanism for antibody bipolar bridging.
|
| |
PLoS Biol,
4,
e148.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
M.I.Gómez,
M.O'Seaghdha,
M.Magargee,
T.J.Foster,
and
A.S.Prince
(2006).
Staphylococcus aureus protein A activates TNFR1 signaling through conserved IgG binding domains.
|
| |
J Biol Chem,
281,
20190-20196.
|
|
|
|
|
|
|
M.O'Seaghdha,
C.J.van Schooten,
S.W.Kerrigan,
J.Emsley,
G.J.Silverman,
D.Cox,
P.J.Lenting,
and
T.J.Foster
(2006).
Staphylococcus aureus protein A binding to von Willebrand factor A1 domain is mediated by conserved IgG binding regions.
|
| |
FEBS J,
273,
4831-4841.
|
|
|
|
|
|
|
R.Jefferis
(2006).
A sugar switch for anti-inflammatory antibodies.
|
| |
Nat Biotechnol,
24,
1230-1231.
|
|
|
|
|
|
|
C.Vaccaro,
J.Zhou,
R.J.Ober,
and
E.S.Ward
(2005).
Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels.
|
| |
Nat Biotechnol,
23,
1283-1288.
|
|
|
|
|
|
|
D.T.Kamei,
B.J.Lao,
M.S.Ricci,
R.Deshpande,
H.Xu,
B.Tidor,
and
D.A.Lauffenburger
(2005).
Quantitative methods for developing Fc mutants with extended half-lives.
|
| |
Biotechnol Bioeng,
92,
748-760.
|
|
|
|
|
|
|
G.J.Silverman,
C.S.Goodyear,
and
D.L.Siegel
(2005).
On the mechanism of staphylococcal protein A immunomodulation.
|
| |
Transfusion,
45,
274-280.
|
|
|
|
|
|
|
H.Chen,
and
H.X.Zhou
(2005).
Prediction of interface residues in protein-protein complexes by a consensus neural network method: test against NMR data.
|
| |
Proteins,
61,
21-35.
|
|
|
|
|
|
|
J.Löfblom,
H.Wernérus,
and
S.Ståhl
(2005).
Fine affinity discrimination by normalized fluorescence activated cell sorting in staphylococcal surface display.
|
| |
FEMS Microbiol Lett,
248,
189-198.
|
|
|
|
|
|
|
J.S.Marvin,
and
Z.Zhu
(2005).
Recombinant approaches to IgG-like bispecific antibodies.
|
| |
Acta Pharmacol Sin,
26,
649-658.
|
|
|
|
|
|
|
N.Rai,
M.Nöllmann,
B.Spotorno,
G.Tassara,
O.Byron,
and
M.Rocco
(2005).
SOMO (SOlution MOdeler) differences between X-Ray- and NMR-derived bead models suggest a role for side chain flexibility in protein hydrodynamics.
|
| |
Structure,
13,
723-734.
|
|
|
|
|
|
|
R.Jefferis
(2005).
Glycosylation of recombinant antibody therapeutics.
|
| |
Biotechnol Prog,
21,
11-16.
|
|
|
|
|
|
|
S.Ghose,
M.Allen,
B.Hubbard,
C.Brooks,
and
S.M.Cramer
(2005).
Antibody variable region interactions with Protein A: implications for the development of generic purification processes.
|
| |
Biotechnol Bioeng,
92,
665-673.
|
|
|
|
|
|
|
T.J.Foster
(2005).
Immune evasion by staphylococci.
|
| |
Nat Rev Microbiol,
3,
948-958.
|
|
|
|
|
|
|
V.Granata,
N.G.Housden,
S.Harrison,
C.Jolivet-Reynaud,
M.G.Gore,
and
E.A.Stura
(2005).
Comparison of the crystallization and crystal packing of two Fab single-site mutant protein L complexes.
|
| |
Acta Crystallogr D Biol Crystallogr,
61,
750-754.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
C.Lendel,
V.Dincbas-Renqvist,
A.Flores,
E.Wahlberg,
J.Dogan,
P.A.Nygren,
and
T.Härd
(2004).
Biophysical characterization of Z(SPA-1)--a phage-display selected binder to protein A.
|
| |
Protein Sci,
13,
2078-2088.
|
|
|
|
|
|
|
D.Zheng,
J.M.Aramini,
and
G.T.Montelione
(2004).
Validation of helical tilt angles in the solution NMR structure of the Z domain of Staphylococcal protein A by combined analysis of residual dipolar coupling and NOE data.
|
| |
Protein Sci,
13,
549-554.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
E.R.Sprague,
W.L.Martin,
and
P.J.Bjorkman
(2004).
pH dependence and stoichiometry of binding to the Fc region of IgG by the herpes simplex virus Fc receptor gE-gI.
|
| |
J Biol Chem,
279,
14184-14193.
|
|
|
|
|
|
|
F.Vinci,
S.Catharino,
S.Frey,
J.Buchner,
G.Marino,
P.Pucci,
and
M.Ruoppolo
(2004).
Hierarchical formation of disulfide bonds in the immunoglobulin Fc fragment is assisted by protein-disulfide isomerase.
|
| |
J Biol Chem,
279,
15059-15066.
|
|
|
|
|
|
|
J.Agniswamy,
B.Lei,
J.M.Musser,
and
P.D.Sun
(2004).
Insight of host immune evasion mediated by two variants of group a Streptococcus Mac protein.
|
| |
J Biol Chem,
279,
52789-52796.
|
|
|
|
|
|
|
J.M.Woof,
and
D.R.Burton
(2004).
Human antibody-Fc receptor interactions illuminated by crystal structures.
|
| |
Nat Rev Immunol,
4,
89-99.
|
|
|
|
|
|
|
M.Collin,
and
V.A.Fischetti
(2004).
A novel secreted endoglycosidase from Enterococcus faecalis with activity on human immunoglobulin G and ribonuclease B.
|
| |
J Biol Chem,
279,
22558-22570.
|
|
|
|
|
|
|
M.Linhult,
S.Gülich,
T.Gräslund,
A.Simon,
M.Karlsson,
A.Sjöberg,
K.Nord,
and
S.Hober
(2004).
Improving the tolerance of a protein a analogue to repeated alkaline exposures using a bypass mutagenesis approach.
|
| |
Proteins,
55,
407-416.
|
|
|
|
|
|
|
P.G.Wolynes
(2004).
Latest folding game results: protein A barely frustrates computationalists.
|
| |
Proc Natl Acad Sci U S A,
101,
6837-6838.
|
|
|
|
|
|
|
T.A.Jones
(2004).
Interactive electron-density map interpretation: from INTER to O.
|
| |
Acta Crystallogr D Biol Crystallogr,
60,
2115-2125.
|
|
|
|
|
|
|
A.B.Herr,
E.R.Ballister,
and
P.J.Bjorkman
(2003).
Insights into IgA-mediated immune responses from the crystal structures of human FcalphaRI and its complex with IgA1-Fc.
|
| |
Nature,
423,
614-620.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
B.A.Wurzburg,
and
T.S.Jardetzky
(2003).
The IgA receptor complex: a two-for-one deal.
|
| |
Nat Struct Biol,
10,
585-587.
|
|
|
|
|
|
|
E.Wahlberg,
C.Lendel,
M.Helgstrand,
P.Allard,
V.Dincbas-Renqvist,
A.Hedqvist,
H.Berglund,
P.A.Nygren,
and
T.Härd
(2003).
An affibody in complex with a target protein: structure and coupled folding.
|
| |
Proc Natl Acad Sci U S A,
100,
3185-3190.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
F.Hadji-Ghasemi,
S.Gharagozlou,
R.Ghods,
A.Roohi,
J.Khoshnoodi,
and
F.Shokri
(2003).
Generation and characterization of a mouse monoclonal antibody with specificity similar to staphylococcal protein A (SPA).
|
| |
Hybrid Hybridomics,
22,
33-39.
|
|
|
|
|
|
|
G.M.Watt,
J.Lund,
M.Levens,
V.S.Kolli,
R.Jefferis,
and
G.J.Boons
(2003).
Site-specific glycosylation of an aglycosylated human IgG1-Fc antibody protein generates neoglycoproteins with enhanced function.
|
| |
Chem Biol,
10,
807-814.
|
|
|
|
|
|
|
H.J.Gould,
B.J.Sutton,
A.J.Beavil,
R.L.Beavil,
N.McCloskey,
H.A.Coker,
D.Fear,
and
L.Smurthwaite
(2003).
The biology of IGE and the basis of allergic disease.
|
| |
Annu Rev Immunol,
21,
579-628.
|
|
|
|
|
|
|
J.A.Vila,
D.R.Ripoll,
and
H.A.Scheraga
(2003).
Atomically detailed folding simulation of the B domain of staphylococcal protein A from random structures.
|
| |
Proc Natl Acad Sci U S A,
100,
14812-14816.
|
|
|
|
|
|
|
K.Johansson,
J.M.Bourhis,
V.Campanacci,
C.Cambillau,
B.Canard,
and
S.Longhi
(2003).
Crystal structure of the measles virus phosphoprotein domain responsible for the induced folding of the C-terminal domain of the nucleoprotein.
|
| |
J Biol Chem,
278,
44567-44573.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
L.Yang,
M.E.Biswas,
and
P.Chen
(2003).
Study of binding between protein A and immunoglobulin G using a surface tension probe.
|
| |
Biophys J,
84,
509-522.
|
|
|
|
|
|
|
M.Högbom,
M.Eklund,
P.A.Nygren,
and
P.Nordlund
(2003).
Structural basis for recognition by an in vitro evolved affibody.
|
| |
Proc Natl Acad Sci U S A,
100,
3191-3196.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
T.Shinkawa,
K.Nakamura,
N.Yamane,
E.Shoji-Hosaka,
Y.Kanda,
M.Sakurada,
K.Uchida,
H.Anazawa,
M.Satoh,
M.Yamasaki,
N.Hanai,
and
K.Shitara
(2003).
The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity.
|
| |
J Biol Chem,
278,
3466-3473.
|
|
|
|
|
|
|
Y.Shimoji,
Y.Ogawa,
M.Osaki,
H.Kabeya,
S.Maruyama,
T.Mikami,
and
T.Sekizaki
(2003).
Adhesive surface proteins of Erysipelothrix rhusiopathiae bind to polystyrene, fibronectin, and type I and IV collagens.
|
| |
J Bacteriol,
185,
2739-2748.
|
|
|
|
|
|
|
A.K.Felts,
E.Gallicchio,
A.Wallqvist,
and
R.M.Levy
(2002).
Distinguishing native conformations of proteins from decoys with an effective free energy estimator based on the OPLS all-atom force field and the Surface Generalized Born solvent model.
|
| |
Proteins,
48,
404-422.
|
|
|
|
|
|
|
E.Boschetti
(2002).
Antibody separation by hydrophobic charge induction chromatography.
|
| |
Trends Biotechnol,
20,
333-337.
|
|
|
|
|
|
|
K.D.White,
and
J.D.Capra
(2002).
Targeting mucosal sites by polymeric immunoglobulin receptor-directed peptides.
|
| |
J Exp Med,
196,
551-555.
|
|
|
|
|
|
|
M.Collin,
M.D.Svensson,
A.G.Sjöholm,
J.C.Jensenius,
U.Sjöbring,
and
A.Olsén
(2002).
EndoS and SpeB from Streptococcus pyogenes inhibit immunoglobulin-mediated opsonophagocytosis.
|
| |
Infect Immun,
70,
6646-6651.
|
|
|
|
|
|
|
M.Eklund,
L.Axelsson,
M.Uhlén,
and
P.A.Nygren
(2002).
Anti-idiotypic protein domains selected from protein A-based affibody libraries.
|
| |
Proteins,
48,
454-462.
|
|
|
|
|
|
|
M.Graille,
S.Harrison,
M.P.Crump,
S.C.Findlow,
N.G.Housden,
B.H.Muller,
N.Battail-Poirot,
G.Sibaï,
B.J.Sutton,
M.J.Taussig,
C.Jolivet-Reynaud,
M.G.Gore,
and
E.A.Stura
(2002).
Evidence for plasticity and structural mimicry at the immunoglobulin light chain-protein L interface.
|
| |
J Biol Chem,
277,
47500-47506.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
M.Holland,
K.Takada,
T.Okumoto,
N.Takahashi,
K.Kato,
D.Adu,
A.Ben-Smith,
L.Harper,
C.O.Savage,
and
R.Jefferis
(2002).
Hypogalactosylation of serum IgG in patients with ANCA-associated systemic vasculitis.
|
| |
Clin Exp Immunol,
129,
183-190.
|
|
|
|
|
|
|
M.U.Johansson,
I.M.Frick,
H.Nilsson,
P.J.Kraulis,
S.Hober,
P.Jonasson,
M.Linhult,
P.A.Nygren,
M.Uhlén,
L.Björck,
T.Drakenberg,
S.Forsén,
and
M.Wikström
(2002).
Structure, specificity, and mode of interaction for bacterial albumin-binding modules.
|
| |
J Biol Chem,
277,
8114-8120.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
P.J.Esteves,
P.C.Alves,
N.Ferrand,
and
W.van der Loo
(2002).
Hotspot variation at the CH2-CH3 interface of leporid IgG antibodies (Oryctolagus, Sylvilagus and Lepus).
|
| |
Eur J Immunogenet,
29,
529-535.
|
|
|
|
|
|
|
P.Vachette,
E.Dainese,
V.B.Vasyliev,
P.Di Muro,
M.Beltramini,
D.I.Svergun,
V.De Filippis,
and
B.Salvato
(2002).
A key structural role for active site type 3 copper ions in human ceruloplasmin.
|
| |
J Biol Chem,
277,
40823-40831.
|
|
|
|
|
|
|
R.L.Shields,
J.Lai,
R.Keck,
L.Y.O'Connell,
K.Hong,
Y.G.Meng,
S.H.Weikert,
and
L.G.Presta
(2002).
Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity.
|
| |
J Biol Chem,
277,
26733-26740.
|
|
|
|
|
|
|
A.B.Edmundson,
G.Tribbick,
S.Plompen,
H.M.Geysen,
E.Yuriev,
and
P.A.Ramsland
(2001).
Binding of synthetic peptides by a human monoclonal IgM with an unusual combining site structure.
|
| |
J Mol Recognit,
14,
229-238.
|
|
|
|
|
|
|
A.Loukas,
M.K.Jones,
L.T.King,
P.J.Brindley,
and
D.P.McManus
(2001).
Receptor for Fc on the surfaces of schistosomes.
|
| |
Infect Immun,
69,
3646-3651.
|
|
|
|
|
|
|
H.Bakker,
M.Bardor,
J.W.Molthoff,
V.Gomord,
I.Elbers,
L.H.Stevens,
W.Jordi,
A.Lommen,
L.Faye,
P.Lerouge,
and
D.Bosch
(2001).
Galactose-extended glycans of antibodies produced by transgenic plants.
|
| |
Proc Natl Acad Sci U S A,
98,
2899-2904.
|
|
|
|
|
|
|
K.D.Scharf,
M.Siddique,
and
E.Vierling
(2001).
The expanding family of Arabidopsis thaliana small heat stress proteins and a new family of proteins containing alpha-crystallin domains (Acd proteins).
|
| |
Cell Stress Chaperones,
6,
225-237.
|
|
|
|
|
|
|
P.M.Rudd,
T.Elliott,
P.Cresswell,
I.A.Wilson,
and
R.A.Dwek
(2001).
Glycosylation and the immune system.
|
| |
Science,
291,
2370-2376.
|
|
|
|
|
|
|
P.Zhu,
W.C.Olson,
and
K.H.Roux
(2001).
Structural flexibility and functional valence of CD4-IgG2 (PRO 542): potential for cross-linking human immunodeficiency virus type 1 envelope spikes.
|
| |
J Virol,
75,
6682-6686.
|
|
|
|
|
|
|
S.Gleiter,
and
H.Lilie
(2001).
Coupling of antibodies via protein Z on modified polyoma virus-like particles.
|
| |
Protein Sci,
10,
434-444.
|
|
|
|
|
|
|
W.L.Martin,
A.P.West,
L.Gan,
and
P.J.Bjorkman
(2001).
Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding.
|
| |
Mol Cell,
7,
867-877.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
Y.Mimura,
P.Sondermann,
R.Ghirlando,
J.Lund,
S.P.Young,
M.Goodall,
and
R.Jefferis
(2001).
Role of oligosaccharide residues of IgG1-Fc in Fc gamma RIIb binding.
|
| |
J Biol Chem,
276,
45539-45547.
|
|
|
|
|
|
|
A.J.Henry,
J.M.McDonnell,
R.Ghirlando,
B.J.Sutton,
and
H.J.Gould
(2000).
Conformation of the isolated cepsilon3 domain of IgE and its complex with the high-affinity receptor, FcepsilonRI.
|
| |
Biochemistry,
39,
7406-7413.
|
|
|
|
|
|
|
B.K.Flesch,
and
J.Neppert
(2000).
Functions of the Fc receptors for immunoglobulin G.
|
| |
J Clin Lab Anal,
14,
141-156.
|
|
|
|
|
|
|
C.A.Waddling,
T.H.Plummer,
A.L.Tarentino,
and
P.Van Roey
(2000).
Structural basis for the substrate specificity of endo-beta-N-acetylglucosaminidase F(3).
|
| |
Biochemistry,
39,
7878-7885.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
D.A.Ostrov,
W.Shi,
J.C.Schwartz,
S.C.Almo,
and
S.G.Nathenson
(2000).
Structure of murine CTLA-4 and its role in modulating T cell responsiveness.
|
| |
Science,
290,
816-819.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
D.P.Meininger,
M.Rance,
M.A.Starovasnik,
W.J.Fairbrother,
and
N.J.Skelton
(2000).
Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment.
|
| |
Biochemistry,
39,
26-36.
|
|
|
|
|
|
|
D.Tortorella,
B.E.Gewurz,
M.H.Furman,
D.J.Schust,
and
H.L.Ploegh
(2000).
Viral subversion of the immune system.
|
| |
Annu Rev Immunol,
18,
861-926.
|
|
|
|
|
|
|
E.J.Sundberg,
and
R.A.Mariuzza
(2000).
Luxury accommodations: the expanding role of structural plasticity in protein-protein interactions.
|
| |
Structure,
8,
R137-R142.
|
|
|
|
|
|
|
H.Zhang,
M.C.Seabra,
and
J.Deisenhofer
(2000).
Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution.
|
| |
Structure,
8,
241-251.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
J.P.Fryer,
J.R.Leventhal,
W.Pao,
C.Stadler,
M.Jones,
T.Walsh,
R.Zhong,
Z.Zhang,
H.Wang,
D.J.Goodman,
M.Kurek,
A.J.d'Apice,
B.Blondin,
D.Ivancic,
F.Buckingham,
D.Kaufman,
M.Abecassis,
F.Stuart,
and
B.E.Anderson
(2000).
Synthetic peptides which inhibit the interaction between C1q and immunoglobulin and prolong xenograft survival.
|
| |
Transplantation,
70,
828-836.
|
|
|
|
|
|
|
M.Graille,
E.A.Stura,
A.L.Corper,
B.J.Sutton,
M.J.Taussig,
J.B.Charbonnier,
and
G.J.Silverman
(2000).
Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity.
|
| |
Proc Natl Acad Sci U S A,
97,
5399-5404.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
N.Opalka,
R.A.Mooney,
C.Richter,
K.Severinov,
R.Landick,
and
S.A.Darst
(2000).
Direct localization of a beta-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase.
|
| |
Proc Natl Acad Sci U S A,
97,
617-622.
|
|
|
|
|
|
|
T.Nguyen,
B.Ghebrehiwet,
and
E.I.Peerschke
(2000).
Staphylococcus aureus protein A recognizes platelet gC1qR/p33: a novel mechanism for staphylococcal interactions with platelets.
|
| |
Infect Immun,
68,
2061-2068.
|
|
|
|
|
|
|
V.Ghetie,
and
E.S.Ward
(2000).
Multiple roles for the major histocompatibility complex class I- related receptor FcRn.
|
| |
Annu Rev Immunol,
18,
739-766.
|
|
|
|
|
|
|
W.L.DeLano,
M.H.Ultsch,
A.M.de Vos,
and
J.A.Wells
(2000).
Convergent solutions to binding at a protein-protein interface.
|
| |
Science,
287,
1279-1283.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
A.Karimi,
M.Matsumura,
P.E.Wright,
and
H.J.Dyson
(1999).
Characterization of monomeric and dimeric B domain of Staphylococcal protein A.
|
| |
J Pept Res,
54,
344-352.
|
|
|
|
|
|
|
B.L.Dickinson,
K.Badizadegan,
Z.Wu,
J.C.Ahouse,
X.Zhu,
N.E.Simister,
R.S.Blumberg,
and
W.I.Lencer
(1999).
Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line.
|
| |
J Clin Invest,
104,
903-911.
|
|
|
|
|
|
|
D.J.Sloan,
and
H.W.Hellinga
(1999).
Dissection of the protein G B1 domain binding site for human IgG Fc fragment.
|
| |
Protein Sci,
8,
1643-1648.
|
|
|
|
|
|
|
I.A.Wilson,
and
L.K.Jolliffe
(1999).
The structure, organization, activation and plasticity of the erythropoietin receptor.
|
| |
Curr Opin Struct Biol,
9,
696-704.
|
|
|
|
|
|
|
I.Sayers,
and
B.A.Helm
(1999).
The structural basis of human IgE-Fc receptor interactions.
|
| |
Clin Exp Allergy,
29,
585-594.
|
|
|
|
|
|
|
J.K.Kim,
M.Firan,
C.G.Radu,
C.H.Kim,
V.Ghetie,
and
E.S.Ward
(1999).
Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn.
|
| |
Eur J Immunol,
29,
2819-2825.
|
|
|
|
|
|
|
J.M.Hexham,
K.D.White,
L.N.Carayannopoulos,
W.Mandecki,
R.Brisette,
Y.S.Yang,
and
J.D.Capra
(1999).
A human immunoglobulin (Ig)A calpha3 domain motif directs polymeric Ig receptor-mediated secretion.
|
| |
J Exp Med,
189,
747-752.
|
|
|
|
|
|
|
K.Andersson,
S.Gülich,
M.Hämäläinen,
P.A.Nygren,
S.Hober,
and
M.Malmqvist
(1999).
Kinetic characterization of the interaction of the Z-fragment of protein A with mouse-IgG3 in a volume in chemical space.
|
| |
Proteins,
37,
494-498.
|
|
|
|
|
|
|
K.C.Garcia,
L.Teyton,
and
I.A.Wilson
(1999).
Structural basis of T cell recognition.
|
| |
Annu Rev Immunol,
17,
369-397.
|
|
|
|
|
|
|
K.L.Armour,
M.R.Clark,
A.G.Hadley,
and
L.M.Williamson
(1999).
Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities.
|
| |
Eur J Immunol,
29,
2613-2624.
|
|
|
|
|
|
|
L.Vangelista,
S.Laffer,
R.Turek,
H.Grönlund,
W.R.Sperr,
P.Valent,
A.Pastore,
and
R.Valenta
(1999).
The immunoglobulin-like modules Cepsilon3 and alpha2 are the minimal units necessary for human IgE-FcepsilonRI interaction.
|
| |
J Clin Invest,
103,
1571-1578.
|
|
|
|
|
|
|
M.A.Starovasnik,
M.P.O'Connell,
W.J.Fairbrother,
and
R.F.Kelley
(1999).
Antibody variable region binding by Staphylococcal protein A: thermodynamic analysis and location of the Fv binding site on E-domain.
|
| |
Protein Sci,
8,
1423-1431.
|
|
|
|
|
|
|
M.H.Seto,
H.L.Liu,
D.A.Zajchowski,
and
M.Whitlow
(1999).
Protein fold analysis of the B30.2-like domain.
|
| |
Proteins,
35,
235-249.
|
|
|
|
|
|
|
M.Léonetti,
J.Galon,
R.Thai,
C.Sautès-Fridman,
G.Moine,
and
A.Ménez
(1999).
Presentation of antigen in immune complexes is boosted by soluble bacterial immunoglobulin binding proteins.
|
| |
J Exp Med,
189,
1217-1228.
|
|
|
|
|
|
|
M.R.Wormald,
and
R.A.Dwek
(1999).
Glycoproteins: glycan presentation and protein-fold stability.
|
| |
Structure,
7,
R155-R160.
|
|
|
|
|
|
|
M.Watson,
P.M.Rudd,
M.Bland,
R.A.Dwek,
and
J.S.Axford
(1999).
Sugar printing rheumatic diseases: a potential method for disease differentiation using immunoglobulin G oligosaccharides.
|
| |
Arthritis Rheum,
42,
1682-1690.
|
|
|
|
|
|
|
P.Sondermann,
R.Huber,
and
U.Jacob
(1999).
Crystal structure of the soluble form of the human fcgamma-receptor IIb: a new member of the immunoglobulin superfamily at 1.7 A resolution.
|
| |
EMBO J,
18,
1095-1103.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
P.Sondermann,
U.Jacob,
C.Kutscher,
and
J.Frey
(1999).
Characterization and crystallization of soluble human Fc gamma receptor II (CD32) isoforms produced in insect cells.
|
| |
Biochemistry,
38,
8469-8477.
|
|
|
|
|
|
|
R.J.Pleass,
J.I.Dunlop,
C.M.Anderson,
and
J.M.Woof
(1999).
Identification of residues in the CH2/CH3 domain interface of IgA essential for interaction with the human fcalpha receptor (FcalphaR) CD89.
|
| |
J Biol Chem,
274,
23508-23514.
|
|
|
|
|
|
|
S.F.Teng,
K.Sproule,
A.Hussain,
and
C.R.Lowe
(1999).
A strategy for the generation of biomimetic ligands for affinity chromatography. Combinatorial synthesis and biological evaluation of an IgG binding ligand.
|
| |
J Mol Recognit,
12,
67-75.
|
|
|
|
|
|
|
T.L.Chapman,
I.You,
I.M.Joseph,
P.J.Bjorkman,
S.L.Morrison,
and
M.Raghavan
(1999).
Characterization of the interaction between the herpes simplex virus type I Fc receptor and immunoglobulin G.
|
| |
J Biol Chem,
274,
6911-6919.
|
|
|
|
|
|
|
W.F.DeGrado,
C.M.Summa,
V.Pavone,
F.Nastri,
and
A.Lombardi
(1999).
De novo design and structural characterization of proteins and metalloproteins.
|
| |
Annu Rev Biochem,
68,
779-819.
|
|
|
|
|
|
|
W.W.Navarre,
and
O.Schneewind
(1999).
Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope.
|
| |
Microbiol Mol Biol Rev,
63,
174-229.
|
|
|
|
|
|
|
A.M.Merchant,
Z.Zhu,
J.Q.Yuan,
A.Goddard,
C.W.Adams,
L.G.Presta,
and
P.Carter
(1998).
An efficient route to human bispecific IgG.
|
| |
Nat Biotechnol,
16,
677-681.
|
|
|
|
|
|
|
A.W.Ashton,
M.K.Boehm,
D.J.Johnson,
G.Kemball-Cook,
and
S.J.Perkins
(1998).
The solution structure of human coagulation factor VIIa in its complex with tissue factor is similar to free factor VIIa: a study of a heterodimeric receptor-ligand complex by X-ray and neutron scattering and computational modeling.
|
| |
Biochemistry,
37,
8208-8217.
|
|
|
|
|
|
|
B.A.Helm,
I.Sayers,
E.A.Padlan,
J.E.McKendrick,
and
A.C.Spivey
(1998).
Structure/function studies on IgE as a basis for the development of rational IgE antagonists.
|
| |
Allergy,
53,
77-82.
|
|
|
|
|
|
|
C.J.Workman,
W.P.Pfund,
and
E.W.Voss
(1998).
Two dual-specific (anti-IgG and anti-dsDNA) monoclonal autoantibodies derived from the NZB/NZW F1 recognize an epitope in the hinge region.
|
| |
J Protein Chem,
17,
599-606.
|
|
|
|
|
|
|
C.Medesan,
P.Cianga,
M.Mummert,
D.Stanescu,
V.Ghetie,
and
E.S.Ward
(1998).
Comparative studies of rat IgG to further delineate the Fc:FcRn interaction site.
|
| |
Eur J Immunol,
28,
2092-2100.
|
|
|
|
|
|
|
C.Mukhopadhyay
(1998).
Molecular dynamics simulation of glycoprotein-glycans of immunoglobulin G and immunoglobulin M.
|
| |
Biopolymers,
45,
177-190.
|
|
|
|
|
|
|
D.Chamberlain,
C.G.Ullman,
and
S.J.Perkins
(1998).
Possible arrangement of the five domains in human complement factor I as determined by a combination of X-ray and neutron scattering and homology modeling.
|
| |
Biochemistry,
37,
13918-13929.
|
|
|
|
|
|
|
D.E.Vaughn,
and
P.J.Bjorkman
(1998).
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor.
|
| |
Structure,
6,
63-73.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
E.Lacroix,
A.R.Viguera,
and
L.Serrano
(1998).
Reading protein sequences backwards.
|
| |
Fold Des,
3,
79-85.
|
|
|
|
|
|
|
E.Muñoz,
L.Vidarte,
C.Pastor,
M.Casado,
and
F.Vivanco
(1998).
A small domain (6.5 kDa) of bacterial protein G inhibits C3 covalent binding to the Fc region of IgG immune complexes.
|
| |
Eur J Immunol,
28,
2591-2597.
|
|
|
|
|
|
|
H.Kovacs,
I.D.Campbell,
P.Strong,
S.Johnson,
F.J.Ward,
K.B.Reid,
and
P.Eggleton
(1998).
Evidence that C1q binds specifically to CH2-like immunoglobulin gamma motifs present in the autoantigen calreticulin and interferes with complement activation.
|
| |
Biochemistry,
37,
17865-17874.
|
|
|
|
|
|
|
I.A.Wilson,
and
P.J.Bjorkman
(1998).
Unusual MHC-like molecules: CD1, Fc receptor, the hemochromatosis gene product, and viral homologs.
|
| |
Curr Opin Immunol,
10,
67-73.
|
|
|
|
|
|
|
I.Sayers,
S.A.Cain,
J.R.Swan,
M.A.Pickett,
P.J.Watt,
S.T.Holgate,
E.A.Padlan,
P.Schuck,
and
B.A.Helm
(1998).
Amino acid residues that influence Fc epsilon RI-mediated effector functions of human immunoglobulin E.
|
| |
Biochemistry,
37,
16152-16164.
|
|
|
|
|
|
|
J.P.Schneider,
A.Lombardi,
and
W.F.DeGrado
(1998).
Analysis and design of three-stranded coiled coils and three-helix bundles.
|
| |
Fold Des,
3,
R29-R40.
|
|
|
|
|
|
|
J.W.Bryson,
J.R.Desjarlais,
T.M.Handel,
and
W.F.DeGrado
(1998).
From coiled coils to small globular proteins: design of a native-like three-helix bundle.
|
| |
Protein Sci,
7,
1404-1414.
|
|
|
|
|
|
|
L.Guan,
L.A.Wims,
R.R.Kane,
M.B.Smuckler,
S.L.Morrison,
and
M.F.Hawthorne
(1998).
Homogeneous immunoconjugates for boron neutron-capture therapy: design, synthesis, and preliminary characterization.
|
| |
Proc Natl Acad Sci U S A,
95,
13206-13210.
|
|
|
|
|
|
|
L.J.Harris,
S.B.Larson,
E.Skaletsky,
and
A.McPherson
(1998).
Comparison of the conformations of two intact monoclonal antibodies with hinges.
|
| |
Immunol Rev,
163,
35-43.
|
|
|
|
|
|
|
N.L.Brown,
S.P.Bottomley,
M.D.Scawen,
and
M.G.Gore
(1998).
A study of the interactions between an IgG-binding domain based on the B domain of staphylococcal protein A and rabbit IgG.
|
| |
Mol Biotechnol,
10,
9.
|
|
|
|
|
|
|
R.Jefferis,
J.Lund,
and
J.D.Pound
(1998).
IgG-Fc-mediated effector functions: molecular definition of interaction sites for effector ligands and the role of glycosylation.
|
| |
Immunol Rev,
163,
59-76.
|
|
|
|
|
|
|
R.Li,
V.Dowd,
D.J.Stewart,
S.J.Burton,
and
C.R.Lowe
(1998).
Design, synthesis, and application of a protein A mimetic.
|
| |
Nat Biotechnol,
16,
190-195.
|
|
|
|
|
|
|
R.Urfer,
P.Tsoulfas,
L.O'Connell,
J.A.Hongo,
W.Zhao,
and
L.G.Presta
(1998).
High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptors.
|
| |
J Biol Chem,
273,
5829-5840.
|
|
|
|
|
|
|
S.Ohnishi,
M.Murata,
and
M.Hato
(1998).
Correlation between surface morphology and surface forces of protein A adsorbed on mica.
|
| |
Biophys J,
74,
455-465.
|
|
|
|
|
|
|
T.S.Mattu,
R.J.Pleass,
A.C.Willis,
M.Kilian,
M.R.Wormald,
A.C.Lellouch,
P.M.Rudd,
J.M.Woof,
and
R.A.Dwek
(1998).
The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fc alpha receptor interactions.
|
| |
J Biol Chem,
273,
2260-2272.
|
|
|
|
|
|
|
V.M.Tischenko,
V.M.Abramov,
and
V.P.Zav'yalov
(1998).
Investigation of the cooperative structure of Fc fragments from myeloma immunoglobulin G.
|
| |
Biochemistry,
37,
5576-5581.
|
|
|
|
|
|
|
V.S.Pande,
and
D.S.Rokhsar
(1998).
Is the molten globule a third phase of proteins?
|
| |
Proc Natl Acad Sci U S A,
95,
1490-1494.
|
|
|
|
|
|
|
W.Dall'Acqua,
A.L.Simon,
M.G.Mulkerrin,
and
P.Carter
(1998).
Contribution of domain interface residues to the stability of antibody CH3 domain homodimers.
|
| |
Biochemistry,
37,
9266-9273.
|
|
|
|
|
|
|
A.Berge,
B.M.Kihlberg,
A.G.Sjöholm,
and
L.Björck
(1997).
Streptococcal protein H forms soluble complement-activating complexes with IgG, but inhibits complement activation by IgG-coated targets.
|
| |
J Biol Chem,
272,
20774-20781.
|
|
|
|
|
|
|
A.L.Corper,
M.K.Sohi,
V.R.Bonagura,
M.Steinitz,
R.Jefferis,
A.Feinstein,
D.Beale,
M.J.Taussig,
and
B.J.Sutton
(1997).
Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction.
|
| |
Nat Struct Biol,
4,
374-381.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
A.L.Lomize,
and
H.I.Mosberg
(1997).
Thermodynamic model of secondary structure for alpha-helical peptides and proteins.
|
| |
Biopolymers,
42,
239-269.
|
|
|
|
|
|
|
A.Wright,
and
S.L.Morrison
(1997).
Effect of glycosylation on antibody function: implications for genetic engineering.
|
| |
Trends Biotechnol,
15,
26-32.
|
|
|
|
|
|
|
J.Shi,
R.Ghirlando,
R.L.Beavil,
A.J.Beavil,
M.B.Keown,
R.J.Young,
R.J.Owens,
B.J.Sutton,
and
H.J.Gould
(1997).
Interaction of the low-affinity receptor CD23/Fc epsilonRII lectin domain with the Fc epsilon3-4 fragment of human immunoglobulin E.
|
| |
Biochemistry,
36,
2112-2122.
|
|
|
|
|
|
|
K.N.Potter,
Y.Li,
V.Pascual,
and
J.D.Capra
(1997).
Staphylococcal protein A binding to VH3 encoded immunoglobulins.
|
| |
Int Rev Immunol,
14,
291-308.
|
|
|
|
|
|
|
K.Nord,
E.Gunneriusson,
J.Ringdahl,
S.Ståhl,
M.Uhlén,
and
P.A.Nygren
(1997).
Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain.
|
| |
Nat Biotechnol,
15,
772-777.
|
|
|
|
|
|
|
M.A.Starovasnik,
A.C.Braisted,
and
J.A.Wells
(1997).
Structural mimicry of a native protein by a minimized binding domain.
|
| |
Proc Natl Acad Sci U S A,
94,
10080-10085.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
M.N.Nedwidek,
and
M.H.Hecht
(1997).
Minimized protein structures: a little goes a long way.
|
| |
Proc Natl Acad Sci U S A,
94,
10010-10011.
|
|
|
|
|
|
|
M.R.Wormald,
P.M.Rudd,
D.J.Harvey,
S.C.Chang,
I.G.Scragg,
and
R.A.Dwek
(1997).
Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharides.
|
| |
Biochemistry,
36,
1370-1380.
|
|
|
|
|
|
|
P.M.Rudd,
and
R.A.Dwek
(1997).
Glycosylation: heterogeneity and the 3D structure of proteins.
|
| |
Crit Rev Biochem Mol Biol,
32,
1.
|
|
|
|
|
|
|
S.Fong,
S.Jones,
M.E.Renz,
H.H.Chiu,
A.M.Ryan,
L.G.Presta,
and
D.Jackson
(1997).
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Its binding motif for alpha 4 beta 7 and role in experimental colitis.
|
| |
Immunol Res,
16,
299-311.
|
|
|
|
|
|
|
T.Haack,
Y.M.Sánchez,
M.J.González,
and
E.Giralt
(1997).
Structural comparison in solution of a native and retro peptide derived from the third helix of Staphylococcus aureus protein A, domain B: retro peptides, a useful tool for the discrimination of helix stabilization factors dependent on the peptide chain orientation.
|
| |
J Pept Sci,
3,
299-313.
|
|
|
|
|
|
|
V.Ghetie,
S.Popov,
J.Borvak,
C.Radu,
D.Matesoi,
C.Medesan,
R.J.Ober,
and
E.S.Ward
(1997).
Increasing the serum persistence of an IgG fragment by random mutagenesis.
|
| |
Nat Biotechnol,
15,
637-640.
|
|
|
|
|
|
|
A.C.Braisted,
and
J.A.Wells
(1996).
Minimizing a binding domain from protein A.
|
| |
Proc Natl Acad Sci U S A,
93,
5688-5692.
|
|
|
|
|
|
|
C.Medesan,
C.Radu,
J.K.Kim,
V.Ghetie,
and
E.S.Ward
(1996).
Localization of the site of the IgG molecule that regulates maternofetal transmission in mice.
|
| |
Eur J Immunol,
26,
2533-2536.
|
|
|
|
|
|
|
D.F.Wyss,
and
G.Wagner
(1996).
The structural role of sugars in glycoproteins.
|
| |
Curr Opin Biotechnol,
7,
409-416.
|
|
|
|
|
|
|
D.J.Leahy,
I.Aukhil,
and
H.P.Erickson
(1996).
2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region.
|
| |
Cell,
84,
155-164.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
D.T.Jones,
C.M.Moody,
J.Uppenbrink,
J.H.Viles,
P.M.Doyle,
C.J.Harris,
L.H.Pearl,
P.J.Sadler,
and
J.M.Thornton
(1996).
Towards meeting the Paracelsus Challenge: The design, synthesis, and characterization of paracelsin-43, an alpha-helical protein with over 50% sequence identity to an all-beta protein.
|
| |
Proteins,
24,
502-513.
|
|
|
|
|
|
|
G.Mer,
H.Hietter,
and
J.F.Lefèvre
(1996).
Stabilization of proteins by glycosylation examined by NMR analysis of a fucosylated proteinase inhibitor.
|
| |
Nat Struct Biol,
3,
45-53.
|
|
|
|
|
|
|
H.Zhang,
Y.Yang,
L.Lai,
and
Y.Tang
(1996).
Conformational analysis of two glycoproteins: a Monte Carlo simulated annealing approach using a soft-sphere potential.
|
| |
Carbohydr Res,
284,
25-34.
|
|
|
|
|
|
|
L.Carayannopoulos,
J.M.Hexham,
and
J.D.Capra
(1996).
Localization of the binding site for the monocyte immunoglobulin (Ig) A-Fc receptor (CD89) to the domain boundary between Calpha2 and Calpha3 in human IgA1.
|
| |
J Exp Med,
183,
1579-1586.
|
|
|
|
|
|
|
L.Jendeberg,
M.Tashiro,
R.Tejero,
B.A.Lyons,
M.Uhlén,
G.T.Montelione,
and
B.Nilsson
(1996).
The mechanism of binding staphylococcal protein A to immunoglobin G does not involve helix unwinding.
|
| |
Biochemistry,
35,
22-31.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
L.Moroder,
D.Besse,
H.J.Musiol,
S.Rudolph-Böhner,
and
F.Siedler
(1996).
Oxidative folding of cystine-rich peptides vs regioselective cysteine pairing strategies.
|
| |
Biopolymers,
40,
207-234.
|
|
|
|
|
|
|
M.A.Starovasnik,
N.J.Skelton,
M.P.O'Connell,
R.F.Kelley,
D.Reilly,
and
W.J.Fairbrother
(1996).
Solution structure of the E-domain of staphylococcal protein A.
|
| |
Biochemistry,
35,
15558-15569.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
M.C.Menziani,
F.Fanelli,
and
P.G.De Benedetti
(1996).
Computational simulations of stem-cell factor/c-kit receptor interaction.
|
| |
Proteins,
26,
42-54.
|
|
|
|
|
|
|
M.Raghavan,
and
P.J.Bjorkman
(1996).
Fc receptors and their interactions with immunoglobulins.
|
| |
Annu Rev Cell Dev Biol,
12,
181-220.
|
|
|
|
|
|
|
M.Wikström,
S.Forsén,
and
T.Drakenberg
(1996).
Backbone dynamics of a domain of protein L which binds to immunoglobulin light chains.
|
| |
Eur J Biochem,
235,
543-548.
|
|
|
|
|
|
|
N.N.Gorgani,
S.B.Easterbrook-Smith,
and
J.G.Altin
(1996).
The formation of insoluble immune complexes between ovalbumin and anti-ovalbumin IgG occurs in at least two distinct phases dependent on reactant concentration and ionic strength.
|
| |
Biochim Biophys Acta,
1317,
45-54.
|
|
|
|
|
|
|
R.Jefferis,
J.Lund,
and
M.Goodall
(1996).
Modulation of Fc(gamma)R and human complement activation by IgG3-core oligosaccharide interactions.
|
| |
Immunol Lett,
54,
101-104.
|
|
|
|
|
|
|
S.E.O'Connor,
and
B.Imperiali
(1996).
Modulation of protein structure and function by asparagine-linked glycosylation.
|
| |
Chem Biol,
3,
803-812.
|
|
|
|
|
|
|
S.Sechi,
P.P.Roller,
J.Willette-Brown,
and
J.P.Kinet
(1996).
A conformational rearrangement upon binding of IgE to its high affinity receptor.
|
| |
J Biol Chem,
271,
19256-19263.
|
|
|
|
|
|
|
V.P.Zav'yalov,
V.M.Abramov,
P.G.Cherepanov,
G.V.Spirina,
T.V.Chernovskaya,
A.M.Vasiliev,
and
G.A.Zav'yalova
(1996).
pH6 antigen (PsaA protein) of Yersinia pestis, a novel bacterial Fc-receptor.
|
| |
FEMS Immunol Med Microbiol,
14,
53-57.
|
|
|
|
|
|
|
A.A.Bergwerff,
C.J.Stroop,
B.Murray,
A.P.Holtorf,
G.Pluschke,
J.Van Oostrum,
J.P.Kamerling,
and
J.F.Vliegenthart
(1995).
Variation in N-linked carbohydrate chains in different batches of two chimeric monoclonal IgG1 antibodies produced by different murine SP2/0 transfectoma cell subclones.
|
| |
Glycoconj J,
12,
318-330.
|
|
|
|
|
|
|
A.E.Sauer-Eriksson,
G.J.Kleywegt,
M.Uhlén,
and
T.A.Jones
(1995).
Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG.
|
| |
Structure,
3,
265-278.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
A.I.Levinson,
L.Kozlowski,
Y.Zheng,
and
L.Wheatley
(1995).
B-cell superantigens: definition and potential impact on the immune response.
|
| |
J Clin Immunol,
15,
26S-36S.
|
|
|
|
|
|
|
A.Kondo,
and
T.Teshima
(1995).
Preparation of immobilized enzyme with high activity using affinity tag based on proteins A and G.
|
| |
Biotechnol Bioeng,
46,
421-428.
|
|
|
|
|
|
|
C.L.Holness,
P.A.Bates,
A.J.Little,
C.D.Buckley,
A.McDowall,
D.Bossy,
N.Hogg,
and
D.L.Simmons
(1995).
Analysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function-associated antigen 1.
|
| |
J Biol Chem,
270,
877-884.
|
|
|
|
|
|
|
J.Janin
(1995).
Elusive affinities.
|
| |
Proteins,
21,
30-39.
|
|
|
|
|
|
|
J.M.Blechman,
and
Y.Yarden
(1995).
Structural aspects of receptor dimerization. c-kit as an example.
|
| |
Ann N Y Acad Sci,
766,
344-362.
|
|
|
|
|
|
|
K.Kato,
L.Y.Lian,
I.L.Barsukov,
J.P.Derrick,
H.Kim,
R.Tanaka,
A.Yoshino,
M.Shiraishi,
I.Shimada,
and
Y.Arata
(1995).
Model for the complex between protein G and an antibody Fc fragment in solution.
|
| |
Structure,
3,
79-85.
|
|
|
|
|
|
|
L.Jendeberg,
B.Persson,
R.Andersson,
R.Karlsson,
M.Uhlén,
and
B.Nilsson
(1995).
Kinetic analysis of the interaction between protein A domain variants and human Fc using plasmon resonance detection.
|
| |
J Mol Recognit,
8,
270-278.
|
|
|
|
|
|
|
M.B.Keown,
R.Ghirlando,
R.J.Young,
A.J.Beavil,
R.J.Owens,
S.J.Perkins,
B.J.Sutton,
and
H.J.Gould
(1995).
Hydrodynamic studies of a complex between the Fc fragment of human IgE and a soluble fragment of the Fc epsilon RI alpha chain.
|
| |
Proc Natl Acad Sci U S A,
92,
1841-1845.
|
|
|
|
|
|
|
M.C.Shao,
and
F.Wold
(1995).
The effect of the protein matrix proximity on glycan reactivity in a glycoprotein model.
|
| |
Eur J Biochem,
228,
79-85.
|
|
|
|
|
|
|
M.Tashiro,
and
G.T.Montelione
(1995).
Structures of bacterial immunoglobulin-binding domains and their complexes with immunoglobulins.
|
| |
Curr Opin Struct Biol,
5,
471-481.
|
|
|
|
|
|
|
P.Carter,
J.Ridgway,
and
Z.Zhu
(1995).
Toward the production of bispecific antibody fragments for clinical applications.
|
| |
J Hematother,
4,
463-470.
|
|
|
|
|
|
|
R.A.Dwek,
A.C.Lellouch,
and
M.R.Wormald
(1995).
Glycobiology: 'the function of sugar in the IgG molecule'.
|
| |
J Anat,
187,
279-292.
|
|
|
|
|
|
|
R.B.Liebert,
and
D.C.Prieve
(1995).
Species-specific long range interactions between receptor/ligand pairs.
|
| |
Biophys J,
69,
66-73.
|
|
|
|
|
|
|
R.M.Stroud,
and
E.B.Fauman
(1995).
Significance of structural changes in proteins: expected errors in refined protein structures.
|
| |
Protein Sci,
4,
2392-2404.
|
|
|
|
|
|
|
R.Malhotra,
M.R.Wormald,
P.M.Rudd,
P.B.Fischer,
R.A.Dwek,
and
R.B.Sim
(1995).
Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein.
|
| |
Nat Med,
1,
237-243.
|
|
|
|
|
|
|
A.A.Adzhubei,
and
M.J.Sternberg
(1994).
Conservation of polyproline II helices in homologous proteins: implications for structure prediction by model building.
|
| |
Protein Sci,
3,
2395-2410.
|
|
|
|
|
|
|
A.Wong,
T.P.Kenny,
R.Ermel,
and
D.L.Robbins
(1994).
IgG3 reactive rheumatoid factor in rheumatoid arthritis: etiologic and pathogenic considerations.
|
| |
Autoimmunity,
19,
199-210.
|
|
|
|
|
|
|
A.Wright,
and
S.L.Morrison
(1994).
Effect of altered CH2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1.
|
| |
J Exp Med,
180,
1087-1096.
|
|
|
|
|
|
|
B.M.Djojonegoro,
M.J.Benedik,
and
R.C.Willson
(1994).
Bacteriophage surface display of an immunoglobulin-binding domain of Staphylococcus aureus protein A.
|
| |
Biotechnology (N Y),
12,
169-172.
|
|
|
|
|
|
|
G.Lange,
S.J.Lewis,
G.N.Murshudov,
G.G.Dodson,
P.C.Moody,
J.P.Turkenburg,
A.N.Barclay,
and
R.L.Brady
(1994).
Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4.
|
| |
Structure,
2,
469-481.
|
|
|
|
|
|
|
H.J.Jansen,
J.S.van der Hoeven,
C.W.van den Kieboom,
J.H.Göertz,
P.J.Camp,
and
J.A.Bakkeren
(1994).
Degradation of immunoglobulin G by periodontal bacteria.
|
| |
Oral Microbiol Immunol,
9,
345-351.
|
|
|
|
|
|
|
I.M.Frick,
P.Akesson,
J.Cooney,
U.Sjöbring,
K.H.Schmidt,
H.Gomi,
S.Hattori,
C.Tagawa,
F.Kishimoto,
and
L.Björck
(1994).
Protein H--a surface protein of Streptococcus pyogenes with separate binding sites for IgG and albumin.
|
| |
Mol Microbiol,
12,
143-151.
|
|
|
|
|
|
|
J.K.Kim,
M.F.Tsen,
V.Ghetie,
and
E.S.Ward
(1994).
Catabolism of the murine IgG1 molecule: evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice.
|
| |
Scand J Immunol,
40,
457-465.
|
|
|
|
|
|
|
J.K.Kim,
M.F.Tsen,
V.Ghetie,
and
E.S.Ward
(1994).
Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor.
|
| |
Eur J Immunol,
24,
2429-2434.
|
|
|
|
|
|
|
J.K.Kim,
M.F.Tsen,
V.Ghetie,
and
E.S.Ward
(1994).
Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site-directed mutagenesis.
|
| |
Eur J Immunol,
24,
542-548.
|
|
|
|
|
|
|
J.U.Bowie,
and
D.Eisenberg
(1994).
An evolutionary approach to folding small alpha-helical proteins that uses sequence information and an empirical guiding fitness function.
|
| |
Proc Natl Acad Sci U S A,
91,
4436-4440.
|
|
|
|
|
|
|
L.Carayannopoulos,
E.E.Max,
and
J.D.Capra
(1994).
Recombinant human IgA expressed in insect cells.
|
| |
Proc Natl Acad Sci U S A,
91,
8348-8352.
|
|
|
|
|
|
|
L.Y.Lian,
I.L.Barsukov,
J.P.Derrick,
and
G.C.Roberts
(1994).
Mapping the interactions between streptococcal protein G and the Fab fragment of IgG in solution.
|
| |
Nat Struct Biol,
1,
355-357.
|
|
|
|
|
|
|
M.Raghavan,
M.Y.Chen,
L.N.Gastinel,
and
P.J.Bjorkman
(1994).
Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand.
|
| |
Immunity,
1,
303-315.
|
|
|
|
|
|
|
O.H.Brekke,
T.E.Michaelsen,
A.Aase,
R.H.Sandin,
and
I.Sandlie
(1994).
Human IgG isotype-specific amino acid residues affecting complement-mediated cell lysis and phagocytosis.
|
| |
Eur J Immunol,
24,
2542-2547.
|
|
|
|
|
|
|
P.N.Nelson,
M.Goodall,
and
R.Jefferis
(1994).
Characterisation of putative monoclonal anti-G3m(u) and anti-G3m(g) reagents and their antigenic determinants.
|
| |
Immunol Invest,
23,
39-45.
|
|
|
|
|
|
|
T.J.Foster,
and
D.McDevitt
(1994).
Surface-associated proteins of Staphylococcus aureus: their possible roles in virulence.
|
| |
FEMS Microbiol Lett,
118,
199-205.
|
|
|
|
|
|
|
W.R.Taylor,
T.P.Flores,
and
C.A.Orengo
(1994).
Multiple protein structure alignment.
|
| |
Protein Sci,
3,
1858-1870.
|
|
|
|
|
|
|
C.M.Fletcher,
R.A.Harrison,
P.J.Lachmann,
and
D.Neuhaus
(1993).
Sequence-specific 1H-NMR assignments and folding topology of human CD59.
|
| |
Protein Sci,
2,
2015-2027.
|
|
|
|
|
|
|
C.R.Ill,
V.M.Keivens,
J.E.Hale,
K.K.Nakamura,
R.A.Jue,
S.Cheng,
E.D.Melcher,
B.Drake,
and
M.C.Smith
(1993).
A COOH-terminal peptide confers regiospecific orientation and facilitates atomic force microscopy of an IgG1.
|
| |
Biophys J,
64,
919-924.
|
|
|
|
|
|
|
I.Randen,
K.N.Potter,
Y.Li,
K.M.Thompson,
V.Pascual,
O.Førre,
J.B.Natvig,
and
J.D.Capra
(1993).
Complementarity-determining region 2 is implicated in the binding of staphylococcal protein A to human immunoglobulin VHIII variable regions.
|
| |
Eur J Immunol,
23,
2682-2686.
|
|
|
|
|
|
|
J.Greenwood,
M.Clark,
and
H.Waldmann
(1993).
Structural motifs involved in human IgG antibody effector functions.
|
| |
Eur J Immunol,
23,
1098-1104.
|
|
|
|
|
|
|
J.L.Hillson,
N.S.Karr,
I.R.Oppliger,
M.Mannik,
and
E.H.Sasso
(1993).
The structural basis of germline-encoded VH3 immunoglobulin binding to staphylococcal protein A.
|
| |
J Exp Med,
178,
331-336.
|
|
|
|
|
|
|
J.Skolnick,
A.Kolinski,
C.L.Brooks,
A.Godzik,
and
A.Rey
(1993).
A method for predicting protein structure from sequence.
|
| |
Curr Biol,
3,
414-423.
|
|
|
|
|
|
|
L.W.Guddat,
J.N.Herron,
and
A.B.Edmundson
(1993).
Three-dimensional structure of a human immunoglobulin with a hinge deletion.
|
| |
Proc Natl Acad Sci U S A,
90,
4271-4275.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
M.H.Tao,
R.I.Smith,
and
S.L.Morrison
(1993).
Structural features of human immunoglobulin G that determine isotype-specific differences in complement activation.
|
| |
J Exp Med,
178,
661-667.
|
|
|
|
|
|
|
H.Kim,
K.Kato,
A.Higuchi,
N.Nomura,
H.Noguchi,
and
Y.Arata
(1992).
13C-NMR spectral analysis of the structures of mouse immunoglobulin G1 carrying allotypes a and j.
|
| |
J Immunol Methods,
153,
223-227.
|
|
|
|
|
|
|
I.M.Frick,
M.Wikström,
S.Forsén,
T.Drakenberg,
H.Gomi,
U.Sjöbring,
and
L.Björck
(1992).
Convergent evolution among immunoglobulin G-binding bacterial proteins.
|
| |
Proc Natl Acad Sci U S A,
89,
8532-8536.
|
|
|
|
|
|
|
J.Gergely,
G.Sármay,
and
E.Rajnavölgyi
(1992).
Regulation of antibody production mediated by Fc gamma receptors, IgG binding factors, and IgG Fc-binding autoantibodies.
|
| |
Crit Rev Biochem Mol Biol,
27,
191-225.
|
|
|
|
|
|
|
J.S.Huston,
C.Cohen,
D.Maratea,
F.Fields,
M.S.Tai,
N.Cabral-Denison,
R.Juffras,
D.C.Rueger,
R.J.Ridge,
and
H.Oppermann
(1992).
Multisite association by recombinant proteins can enhance binding selectivity. Preferential removal of immune complexes from serum by immobilized truncated FB analogues of the B domain from staphylococcal protein A.
|
| |
Biophys J,
62,
87-91.
|
|
|
|
|
|
|
S.E.Artandi,
K.L.Calame,
S.L.Morrison,
and
V.R.Bonagura
(1992).
Monoclonal IgM rheumatoid factors bind IgG at a discontinuous epitope comprised of amino acid loops from heavy-chain constant-region domains 2 and 3.
|
| |
Proc Natl Acad Sci U S A,
89,
94-98.
|
|
|
|
|
|
|
S.U.Shin,
A.Wright,
V.Bonagura,
and
S.L.Morrison
(1992).
Genetically-engineered antibodies: tools for the study of diverse properties of the antibody molecule.
|
| |
Immunol Rev,
130,
87.
|
|
|
|
|
|
|
V.R.Bonagura,
S.E.Artandi,
N.Agostino,
M.H.Tao,
and
S.L.Morrison
(1992).
Mapping rheumatoid factor binding sites using genetically engineered, chimeric IgG antibodies.
|
| |
DNA Cell Biol,
11,
245-252.
|
|
|
|
|
|
|
A.Imberty,
M.M.Delage,
Y.Bourne,
C.Cambillau,
and
S.Pérez
(1991).
Data bank of three-dimensional structures of disaccharides: Part II, N-acetyllactosaminic type N-glycans. Comparison with the crystal structure of a biantennary octasaccharide.
|
| |
Glycoconj J,
8,
456-483.
|
|
|
|
|
|
|
A.P.Korn,
and
R.M.Burnett
(1991).
Distribution and complementarity of hydropathy in multisubunit proteins.
|
| |
Proteins,
9,
37-55.
|
|
|
|
|
|
|
A.Volbeda,
A.Lahm,
F.Sakiyama,
and
D.Suck
(1991).
Crystal structure of Penicillium citrinum P1 nuclease at 2.8 A resolution.
|
| |
EMBO J,
10,
1607-1618.
|
|
|
|
|
|
|
A.Wright,
M.H.Tao,
E.A.Kabat,
and
S.L.Morrison
(1991).
Antibody variable region glycosylation: position effects on antigen binding and carbohydrate structure.
|
| |
EMBO J,
10,
2717-2723.
|
|
|
|
|
|
|
B.A.Helm,
Y.Ling,
C.Teale,
E.A.Padlan,
and
M.Brüggemann
(1991).
The nature and importance of the inter-epsilon chain disulfide bonds in human IgE.
|
| |
Eur J Immunol,
21,
1543-1548.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
H.R.Griffiths,
and
J.Lunec
(1991).
Effects of reactive oxygen species on immunoglobulin G function.
|
| |
Mol Aspects Med,
12,
107-119.
|
|
|
|
|
|
|
J.E.McCartney,
L.Lederman,
E.A.Drier,
N.A.Cabral-Denison,
G.M.Wu,
R.S.Batorsky,
J.S.Huston,
and
H.Oppermann
(1991).
Biosynthetic antibody binding sites: development of a single-chain Fv model based on antidinitrophenol IgA myeloma MOPC 315.
|
| |
J Protein Chem,
10,
669-683.
|
|
|
|
|
|
|
J.Mazurier,
M.Dauchez,
G.Vergoten,
J.Montreuil,
and
G.Spik
(1991).
Molecular modeling of a disialylated monofucosylated biantennary glycan of the N-acetyllactosamine type.
|
| |
Glycoconj J,
8,
390-399.
|
|
|
|
|
|
|
L.Norderhaug,
O.H.Brekke,
B.Bremnes,
R.Sandin,
A.Aase,
T.E.Michaelsen,
and
I.Sandlie
(1991).
Chimeric mouse human IgG3 antibodies with an IgG4-like hinge region induce complement-mediated lysis more efficiently than IgG3 with normal hinge.
|
| |
Eur J Immunol,
21,
2379-2384.
|
|
|
|
|
|
|
M.C.Tedford,
and
W.H.Stimson
(1991).
Molecular recognition in antibodies and its application.
|
| |
Experientia,
47,
1129-1138.
|
|
|
|
|
|
|
M.H.Tao,
S.M.Canfield,
and
S.L.Morrison
(1991).
The differential ability of human IgG1 and IgG4 to activate complement is determined by the COOH-terminal sequence of the CH2 domain.
|
| |
J Exp Med,
173,
1025-1028.
|
|
|
|
|
|
|
M.S.Chappel,
D.E.Isenman,
M.Everett,
Y.Y.Xu,
K.J.Dorrington,
and
M.H.Klein
(1991).
Identification of the Fc gamma receptor class I binding site in human IgG through the use of recombinant IgG1/IgG2 hybrid and point-mutated antibodies.
|
| |
Proc Natl Acad Sci U S A,
88,
9036-9040.
|
|
|
|
|
|
|
S.O.Lee,
and
R.D.Poretz
(1991).
Hybrid myeloma cells which secrete heterodimeric IgG: a model to study the N-linked glycan.
|
| |
Immunol Cell Biol,
69,
151-157.
|
|
|
|
|
|
|
D.G.Heath,
M.D.Boyle,
and
P.P.Cleary
(1990).
Isolated DNA repeat region from fcrA76, the Fc-binding protein gene from an M-type 76 strain of group A streptococci, encodes a protein with Fc-binding activity.
|
| |
Mol Microbiol,
4,
2071-2079.
|
|
|
|
|
|
|
D.R.Burton
(1990).
Antibody: the flexible adaptor molecule.
|
| |
Trends Biochem Sci,
15,
64-69.
|
|
|
|
|
|
|
E.A.Padlan
(1990).
On the nature of antibody combining sites: unusual structural features that may confer on these sites an enhanced capacity for binding ligands.
|
| |
Proteins,
7,
112-124.
|
|
|
|
|
|
|
M.S.Johnson,
M.J.Sutcliffe,
and
T.L.Blundell
(1990).
Molecular anatomy: phyletic relationships derived from three-dimensional structures of proteins.
|
| |
J Mol Evol,
30,
43-59.
|
|
|
|
|
|
|
R.Stuike-Prill,
and
B.Meyer
(1990).
A new force-field program for the calculation of glycopeptides and its application to a heptacosapeptide-decasaccharide of immunoglobulin G1. Importance of 1-6-glycosidic linkages in carbohydrate.peptide interactions.
|
| |
Eur J Biochem,
194,
903-919.
|
|
|
|
|
|
|
T.E.Michaelsen,
A.Aase,
C.Westby,
and
I.Sandlie
(1990).
Enhancement of complement activation and cytolysis of human IgG3 by deletion of hinge exons.
|
| |
Scand J Immunol,
32,
517-528.
|
|
|
|
|
|
|
T.Martin,
A.M.Knapp,
S.Muller,
and
J.L.Pasquali
(1990).
Polyclonal human rheumatoid factors cross-reacting with histone H3: characterization of an idiotope on the H3 binding site.
|
| |
J Clin Immunol,
10,
211-219.
|
|
|
|
|
|
|
V.L.Giranda,
M.S.Chapman,
and
M.G.Rossmann
(1990).
Modeling of the human intercellular adhesion molecule-1, the human rhinovirus major group receptor.
|
| |
Proteins,
7,
227-233.
|
|
|
|
|
|
|
C.Ljungquist,
B.Jansson,
T.Moks,
and
M.Uhlén
(1989).
Thiol-directed immobilization of recombinant IgG-binding receptors.
|
| |
Eur J Biochem,
186,
557-561.
|
|
|
|
|
|
|
M.B.Dürrenberger
(1989).
Removal of background label in immunocytochemistry with the apolar Lowicryls by using washed protein A-gold-precoupled antibodies in a one-step procedure.
|
| |
J Electron Microsc Tech,
11,
109-116.
|
|
|
|
|
|
|
M.Nose,
and
T.Leanderson
(1989).
Substitution of asparagine324 with aspartic acid in the Fc portion of mouse antibodies reduces their capacity for C1q binding.
|
| |
Eur J Immunol,
19,
2179-2181.
|
|
|
|
|
|
|
R.C.Burnett,
W.C.Hanly,
S.K.Zhai,
and
K.L.Knight
(1989).
The IgA heavy-chain gene family in rabbit: cloning and sequence analysis of 13 C alpha genes.
|
| |
EMBO J,
8,
4041-4047.
|
|
|
|
|
|
|
H.Matsumoto
(1988).
Characteristics of Mongoloid and neighboring populations based on the genetic markers of human immunoglobulins.
|
| |
Hum Genet,
80,
207-218.
|
|
|
|
|
|
|
M.J.Santoni,
C.Goridis,
and
J.C.Fontecilla-Camps
(1988).
Molecular modelling of the immunoglobulin-like domains of the neural cell adhesion molecule (NCAM): implications for the positioning of functionally important sugar side chains.
|
| |
J Neurosci Res,
20,
304-310.
|
|
|
|
|
|
|
M.L.Yarmush,
and
W.C.Olson
(1988).
Electrophoretic elution from biospecific adsorbents: principles, methodology, and applications.
|
| |
Electrophoresis,
9,
111-120.
|
|
|
|
|
|
|
R.A.Mageed,
D.A.Carson,
and
R.Jefferis
(1988).
Immunogenic and antigenic epitopes of immunoglobulins. XXIII. Idiotypy and molecular specificity of human rheumatoid factors: analysis of cross-reactive idiotype of rheumatoid factor paraproteins from the Wa idiotype group in relation to their IgG subclass specificity.
|
| |
Scand J Immunol,
28,
233-240.
|
|
|
|
|
|
|
M.J.Shulman,
C.Collins,
N.Pennell,
and
N.Hozumi
(1987).
Complement activation by IgM: evidence for the importance of the third constant domain of the mu heavy chain.
|
| |
Eur J Immunol,
17,
549-554.
|
|
|
|
|
|
|
N.R.Gascoigne,
C.C.Goodnow,
K.I.Dudzik,
V.T.Oi,
and
M.M.Davis
(1987).
Secretion of a chimeric T-cell receptor-immunoglobulin protein.
|
| |
Proc Natl Acad Sci U S A,
84,
2936-2940.
|
|
|
|
|
|
|
W.P.Schneider,
V.T.Oi,
and
C.Yanofsky
(1987).
Hybrid immunoglobulin isotypes of identical specificity produced by genetic recombination in Escherichia coli and expression in lymphoid cells.
|
| |
Proteins,
2,
81-89.
|
|
|
|
|
|
|
B.Guss,
M.Eliasson,
A.Olsson,
M.Uhlén,
A.K.Frej,
H.Jörnvall,
J.I.Flock,
and
M.Lindberg
(1986).
Structure of the IgG-binding regions of streptococcal protein G.
|
| |
EMBO J,
5,
1567-1575.
|
|
|
|
|
|
|
H.Paulsen,
T.Peters,
V.Sinnwell,
M.Heume,
and
B.Meyer
(1986).
[Conformational analysis of the double pentasaccharide sequence of the "bisected" structure ov N-glycoproteins].
|
| |
Carbohydr Res,
156,
87.
|
|
|
|
|
|
|
J.J.Beintema
(1986).
Do asparagine-linked carbohydrate chains in glycoproteins have a preference for beta-bends?
|
| |
Biosci Rep,
6,
709-714.
|
|
|
|
|
|
|
J.Novotný,
S.Tonegawa,
H.Saito,
D.M.Kranz,
and
H.N.Eisen
(1986).
Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains.
|
| |
Proc Natl Acad Sci U S A,
83,
742-746.
|
|
|
|
|
|
|
T.Moks,
L.Abrahmsén,
B.Nilsson,
U.Hellman,
J.Sjöquist,
and
M.Uhlén
(1986).
Staphylococcal protein A consists of five IgG-binding domains.
|
| |
Eur J Biochem,
156,
637-643.
|
|
|
|
|
|
|
F.A.Nardella,
D.C.Teller,
C.V.Barber,
and
M.Mannik
(1985).
IgG rheumatoid factors and staphylococcal protein A bind to a common molecular site on IgG.
|
| |
J Exp Med,
162,
1811-1824.
|
|
|
|
|
|
|
G.Bruin,
A.Faber,
and
J.Biewenga
(1985).
Binding of human IgA fragments to protein A-Sepharose studied with an ELISA method.
|
| |
Scand J Immunol,
21,
49-54.
|
|
|
|
|
|
|
J.W.Becker,
and
G.N.Reeke
(1985).
Three-dimensional structure of beta 2-microglobulin.
|
| |
Proc Natl Acad Sci U S A,
82,
4225-4229.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
J.Zikan,
J.Novotny,
T.L.Trapane,
M.E.Koshland,
D.W.Urry,
J.C.Bennett,
and
J.Mestecky
(1985).
Secondary structure of the immunoglobulin J chain.
|
| |
Proc Natl Acad Sci U S A,
82,
5905-5909.
|
|
|
|
|
|
|
P.Ferrier,
J.C.Fontecilla-Camps,
D.Bucchini,
D.H.Caillol,
B.R.Jordan,
and
F.A.Lemonnier
(1985).
Altered structure of HLA class I heavy chains associated with mouse beta-2 microglobulin.
|
| |
Immunogenetics,
21,
321-331.
|
|
|
|
|
|
|
A.N.Theofilopoulos,
R.S.Balderas,
L.Hang,
and
F.J.Dixon
(1983).
Monoclonal IgM rheumatoid factors derived from arthritic MRL/Mp-lpr/lpr mice.
|
| |
J Exp Med,
158,
901-919.
|
|
|
|
|
|
|
K.E.Bernstein,
C.B.Alexander,
and
R.G.Mage
(1983).
Nucleotide sequence of a rabbit IgG heavy chain from the recombinant F-I haplotype.
|
| |
Immunogenetics,
18,
387-397.
|
|
|
|
|
|
|
O.Epp,
R.Ladenstein,
and
A.Wendel
(1983).
The refined structure of the selenoenzyme glutathione peroxidase at 0.2-nm resolution.
|
| |
Eur J Biochem,
133,
51-69.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
R.Huber,
and
W.S.Bennett
(1983).
Functional significance of flexibility in proteins.
|
| |
Biopolymers,
22,
261-279.
|
|
|
|
|
|
|
S.Dima,
C.Medeşan,
G.Moţa,
I.Moraru,
J.Sjöquist,
and
V.Gheţie
(1983).
Effect of protein A and its fragment B on the catabolic and Fc receptor sites of IgG.
|
| |
Eur J Immunol,
13,
605-614.
|
|
|
|
|
|
|
V.T.Oi,
A.N.Glazer,
and
L.Stryer
(1982).
Fluorescent phycobiliprotein conjugates for analyses of cells and molecules.
|
| |
J Cell Biol,
93,
981-986.
|
|
|
|
|
|
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so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
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|
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