PDBsum entry: 1eqv

Hydrolase

PDB id: 1eqv

Contents

Protein chain

136 a.a. *

Waters ×38

* Residue conservation analysis

PDB id:

1eqv

Name:

Hydrolase

Title:

Simplification of a protein loop in staphylococcal nuclease

Structure:

Thermonuclease. Chain: a. Engineered: yes. Mutation: yes

Source:

Staphylococcus aureus. Organism_taxid: 1280. Strain: foggi. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.94Å R-factor: 0.192

Authors:

A.Hodel,P.C.Harkins,D.M.Adelman,M.A.White,R.O.Fox

Key ref:

A.Hodel et al. Simplification of a protein loop in staphylococcal nuclease. To be published,

Date:

06-Apr-00 Release date: 08-Jul-03

Protein chain

P00644  (NUC_STAAU) -  Thermonuclease

Seq: 231 a.a.

Struc: 136 a.a.*

* PDB and UniProt seqs differ at 4 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.1.31.1 - Micrococcal nuclease.
• Reaction: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.

 Gene Ontology (GO) functional annotation 

• Biochemical function: nucleic acid binding (3 terms)