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PDBsum entry 1eff

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protein ligands links
Hydrolase/hydrolase inhibitor PDB id
1eff
Jmol
Contents
Protein chain
212 a.a.
Ligands
NNS
MOH
Waters ×615
Theoretical model
PDB id:
1eff
Name: Hydrolase/hydrolase inhibitor
Title: Knowledge based model of an inhibitor bound to a thiol(cystein) protease, papain complexed with napqi
Structure: Papain. Chain: a. Ec: 3.4.22.2
Source: Carica papaya. Papaya. Organ: fruit. Secretion: latex
Authors: A.Banerjee,A.K.Pal,S.Bhattacharyya
Key ref: A.Banerjee et al. Structural basis of inactivation of thiol protease by imine (napqi). A knowledge based molecular modelling study of the adduct of napqi with the thiol protease of papain family.. To be published, .
Date:
08-Feb-00     Release date:   15-Mar-00    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00784  (PAPA1_CARPA) -  Papain
Seq:
Struc:
345 a.a.
212 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.4.22.2  - Papain.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic sidechain at the P2 position. Does not accept Val at P1'.