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PDBsum entry 1dmo
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Calcium-binding protein
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PDB id
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1dmo
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Contents |
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* Residue conservation analysis
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Nat Struct Biol
2:758-767
(1995)
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PubMed id:
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Calcium-induced conformational transition revealed by the solution structure of apo calmodulin.
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M.Zhang,
T.Tanaka,
M.Ikura.
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ABSTRACT
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The solution structure of Ca(2+)-free calmodulin has been determined by NMR
spectroscopy, and is compared to the previously reported structure of the
Ca(2+)-saturated form. The removal of Ca2+ causes the interhelical angles of
four EF-hand motifs to increase by 36 degrees-44 degrees. This leads to major
changes in surface properties, including the closure of the deep hydrophobic
cavity essential for target protein recognition. Concerted movements of helices
A and D with respect to B and C, and of helices E and H with respect to F and G
are likely responsible for the cooperative Ca(2+)-binding property observed
between two adjacent EF-hand sites in the amino- and carboxy-terminal domains.
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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E.Project,
E.Nachliel,
and
M.Gutman
(2011).
The Dynamics of Ca Ions within the Solvation Shell of Calbindin D9k.
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PLoS One,
6,
e14718.
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J.L.Gifford,
H.Ishida,
and
H.J.Vogel
(2011).
Fast methionine-based solution structure determination of calcium-calmodulin complexes.
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J Biomol NMR,
50,
71-81.
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PDB code:
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K.Chandra,
V.Ramakrishnan,
Y.Sharma,
and
K.V.Chary
(2011).
N-terminal myristoylation alters the calcium binding pathways in neuronal calcium sensor-1.
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J Biol Inorg Chem,
16,
81-95.
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L.Santamaria-Kisiel,
and
G.S.Shaw
(2011).
Identification of regions responsible for the open conformation of S100A10 using chimaeric S100A11-S100A10 proteins.
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Biochem J,
434,
37-48.
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W.Ohashi,
H.Hirota,
and
T.Yamazaki
(2011).
Solution structure and fluctuation of the Mg(2+)-bound form of calmodulin C-terminal domain.
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Protein Sci,
20,
690-701.
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PDB code:
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Z.Grabarek
(2011).
Insights into modulation of calcium signaling by magnesium in calmodulin, troponin C and related EF-hand proteins.
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Biochim Biophys Acta,
1813,
913-921.
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C.C.Wei,
N.Motl,
K.Levek,
L.Q.Chen,
Y.P.Yang,
T.Johnson,
L.Hamilton,
and
D.J.Stuehr
(2010).
Conformational States and kinetics of the calcium binding domain of NADPH oxidase 5.
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Open Biochem J,
4,
59-67.
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F.Rodríguez-Castañeda,
M.Maestre-Martínez,
N.Coudevylle,
K.Dimova,
H.Junge,
N.Lipstein,
D.Lee,
S.Becker,
N.Brose,
O.Jahn,
T.Carlomagno,
and
C.Griesinger
(2010).
Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity.
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EMBO J,
29,
680-691.
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PDB code:
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H.Huang,
H.Ishida,
and
H.J.Vogel
(2010).
The solution structure of the Mg2+ form of soybean calmodulin isoform 4 reveals unique features of plant calmodulins in resting cells.
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Protein Sci,
19,
475-485.
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PDB code:
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J.L.Kitevski-Leblanc,
F.Evanics,
and
R.Scott Prosser
(2010).
Approaches to the assignment of (19)F resonances from 3-fluorophenylalanine labeled calmodulin using solution state NMR.
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J Biomol NMR,
47,
113-123.
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L.W.Xiong,
Q.K.Kleerekoper,
X.Wang,
and
J.A.Putkey
(2010).
Intra- and interdomain effects due to mutation of calcium-binding sites in calmodulin.
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J Biol Chem,
285,
8094-8103.
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M.D.Feldkamp,
S.E.O'Donnell,
L.Yu,
and
M.A.Shea
(2010).
Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin.
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Proteins,
78,
2265-2282.
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N.Uchikoga,
and
T.Hirokawa
(2010).
Analysis of protein-protein docking decoys using interaction fingerprints: application to the reconstruction of CaM-ligand complexes.
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BMC Bioinformatics,
11,
236.
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A.P.Yamniuk,
H.Ishida,
D.Lippert,
and
H.J.Vogel
(2009).
Thermodynamic effects of noncoded and coded methionine substitutions in calmodulin.
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Biophys J,
96,
1495-1507.
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C.Li,
J.Chan,
F.Haeseleer,
K.Mikoshiba,
K.Palczewski,
M.Ikura,
and
J.B.Ames
(2009).
Structural Insights into Ca2+-dependent Regulation of Inositol 1,4,5-Trisphosphate Receptors by CaBP1.
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J Biol Chem,
284,
2472-2481.
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D.Yamamoto,
N.Nagura,
S.Omote,
M.Taniguchi,
and
T.Ando
(2009).
Streptavidin 2D crystal substrates for visualizing biomolecular processes by atomic force microscopy.
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Biophys J,
97,
2358-2367.
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E.Laine,
A.Blondel,
and
T.E.Malliavin
(2009).
Dynamics and energetics: a consensus analysis of the impact of calcium on EF-CaM protein complex.
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Biophys J,
96,
1249-1263.
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G.Loving,
and
B.Imperiali
(2009).
Thiol-reactive derivatives of the solvatochromic 4-N,N-dimethylamino-1,8-naphthalimide fluorophore: a highly sensitive toolset for the detection of biomolecular interactions.
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Bioconjug Chem,
20,
2133-2141.
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G.Meissner,
D.A.Pasek,
N.Yamaguchi,
S.Ramachandran,
N.V.Dokholyan,
and
A.Tripathy
(2009).
Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.
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Proteins,
74,
207-211.
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I.Bertini,
S.Das Gupta,
X.Hu,
T.Karavelas,
C.Luchinat,
G.Parigi,
and
J.Yuan
(2009).
Solution structure and dynamics of S100A5 in the apo and Ca2+-bound states.
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J Biol Inorg Chem,
14,
1097-1107.
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PDB codes:
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J.Akerboom,
J.D.Rivera,
M.M.Guilbe,
E.C.Malavé,
H.H.Hernandez,
L.Tian,
S.A.Hires,
J.S.Marvin,
L.L.Looger,
and
E.R.Schreiter
(2009).
Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design.
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J Biol Chem,
284,
6455-6464.
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PDB codes:
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J.L.Kitevski-LeBlanc,
F.Evanics,
and
R.S.Prosser
(2009).
Approaches for the measurement of solvent exposure in proteins by 19F NMR.
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J Biomol NMR,
45,
255-264.
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J.L.Li,
C.Y.Geng,
Y.Bu,
X.R.Huang,
and
C.C.Sun
(2009).
Conformational transition pathway in the allosteric process of calcium-induced recoverin: molecular dynamics simulations.
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J Comput Chem,
30,
1135-1145.
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J.P.Junker,
F.Ziegler,
and
M.Rief
(2009).
Ligand-dependent equilibrium fluctuations of single calmodulin molecules.
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Science,
323,
633-637.
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R.M.Hoffman,
and
B.D.Sykes
(2009).
Structure of the inhibitor W7 bound to the regulatory domain of cardiac troponin C.
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Biochemistry,
48,
5541-5552.
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PDB code:
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S.Dobney,
D.Chiasson,
P.Lam,
S.P.Smith,
and
W.A.Snedden
(2009).
The calmodulin-related calcium sensor CML42 plays a role in trichome branching.
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J Biol Chem,
284,
31647-31657.
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V.Borsi,
C.Luchinat,
and
G.Parigi
(2009).
Global and local mobility of apocalmodulin monitored through fast-field cycling relaxometry.
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Biophys J,
97,
1765-1771.
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B.Kim,
and
A.Chilkoti
(2008).
Allosteric actuation of inverse phase transition of a stimulus-responsive fusion polypeptide by ligand binding.
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J Am Chem Soc,
130,
17867-17873.
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E.Johnson,
L.Bruschweiler-Li,
S.A.Showalter,
G.W.Vuister,
F.Zhang,
and
R.Brüschweiler
(2008).
Structure and dynamics of Ca2+-binding domain 1 of the Na+/Ca2+ exchanger in the presence and in the absence of Ca2+.
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J Mol Biol,
377,
945-955.
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E.Laine,
J.D.Yoneda,
A.Blondel,
and
T.E.Malliavin
(2008).
The conformational plasticity of calmodulin upon calcium complexation gives a model of its interaction with the oedema factor of Bacillus anthracis.
|
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Proteins,
71,
1813-1829.
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E.M.Jones,
T.C.Squier,
and
C.A.Sacksteder
(2008).
An altered mode of calcium coordination in methionine-oxidized calmodulin.
|
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Biophys J,
95,
5268-5280.
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J.Gsponer,
J.Christodoulou,
A.Cavalli,
J.M.Bui,
B.Richter,
C.M.Dobson,
and
M.Vendruscolo
(2008).
A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction.
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Structure,
16,
736-746.
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PDB codes:
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J.N.Wingard,
J.Ladner,
M.Vanarotti,
A.J.Fisher,
H.Robinson,
K.T.Buchanan,
D.M.Engman,
and
J.B.Ames
(2008).
Structural Insights into Membrane Targeting by the Flagellar Calcium-binding Protein (FCaBP), a Myristoylated and Palmitoylated Calcium Sensor in Trypanosoma cruzi.
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J Biol Chem,
283,
23388-23396.
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PDB code:
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K.M.Trybus
(2008).
Myosin V from head to tail.
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Cell Mol Life Sci,
65,
1378-1389.
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N.V.Valeyev,
D.G.Bates,
P.Heslop-Harrison,
I.Postlethwaite,
and
N.V.Kotov
(2008).
Elucidating the mechanisms of cooperative calcium-calmodulin interactions: a structural systems biology approach.
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BMC Syst Biol,
2,
48.
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N.V.Valeyev,
P.Heslop-Harrison,
I.Postlethwaite,
N.V.Kotov,
and
D.G.Bates
(2008).
Multiple calcium binding sites make calmodulin multifunctional.
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Mol Biosyst,
4,
66-73.
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Q.Guo,
J.E.Jureller,
J.T.Warren,
E.Solomaha,
J.Florián,
and
W.J.Tang
(2008).
Protein-protein docking and analysis reveal that two homologous bacterial adenylyl cyclase toxins interact with calmodulin differently.
|
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J Biol Chem,
283,
23836-23845.
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R.A.Newman,
W.S.Van Scyoc,
B.R.Sorensen,
O.R.Jaren,
and
M.A.Shea
(2008).
Interdomain cooperativity of calmodulin bound to melittin preferentially increases calcium affinity of sites I and II.
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Proteins,
71,
1792-1812.
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S.Malik,
M.Revington,
S.P.Smith,
and
G.S.Shaw
(2008).
Analysis of the structure of human apo-S100B at low temperature indicates a unimodal conformational distribution is adopted by calcium-free S100 proteins.
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Proteins,
73,
28-42.
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PDB code:
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S.Tripathi,
and
J.J.Portman
(2008).
Inherent flexibility and protein function: The open/closed conformational transition in the N-terminal domain of calmodulin.
|
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J Chem Phys,
128,
205104.
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T.Ly,
and
R.R.Julian
(2008).
Protein-metal interactions of calmodulin and alpha-synuclein monitored by selective noncovalent adduct protein probing mass spectrometry.
|
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J Am Soc Mass Spectrom,
19,
1663-1672.
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A.Isvoran,
C.T.Craescu,
and
E.Alexov
(2007).
Electrostatic control of the overall shape of calmodulin: numerical calculations.
|
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Eur Biophys J,
36,
225-237.
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A.Uttenweiler,
H.Schwarz,
H.Neumann,
and
A.Mayer
(2007).
The vacuolar transporter chaperone (VTC) complex is required for microautophagy.
|
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Mol Biol Cell,
18,
166-175.
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F.Edlich,
M.Maestre-Martínez,
F.Jarczowski,
M.Weiwad,
M.C.Moutty,
M.Malesević,
G.Jahreis,
G.Fischer,
and
C.Lücke
(2007).
A novel calmodulin-Ca2+ target recognition activates the Bcl-2 regulator FKBP38.
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J Biol Chem,
282,
36496-36504.
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J.S.Sharp,
and
K.B.Tomer
(2007).
Analysis of the oxidative damage-induced conformational changes of apo- and holocalmodulin by dose-dependent protein oxidative surface mapping.
|
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Biophys J,
92,
1682-1692.
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K.M.Trybus,
M.I.Gushchin,
H.Lui,
L.Hazelwood,
E.B.Krementsova,
N.Volkmann,
and
D.Hanein
(2007).
Effect of calcium on calmodulin bound to the IQ motifs of myosin V.
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J Biol Chem,
282,
23316-23325.
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L.Settimo,
S.Donnini,
A.H.Juffer,
R.W.Woody,
and
O.Marin
(2007).
Conformational changes upon calcium binding and phosphorylation in a synthetic fragment of calmodulin.
|
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Biopolymers,
88,
373-385.
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M.Rainaldi,
A.P.Yamniuk,
T.Murase,
and
H.J.Vogel
(2007).
Calcium-dependent and -independent binding of soybean calmodulin isoforms to the calmodulin binding domain of tobacco MAPK phosphatase-1.
|
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J Biol Chem,
282,
6031-6042.
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N.Juranić,
E.Atanasova,
J.H.Streiff,
S.Macura,
and
F.G.Prendergast
(2007).
Solvent-induced differentiation of protein backbone hydrogen bonds in calmodulin.
|
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Protein Sci,
16,
1329-1337.
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S.L.Russell,
N.V.McFerran,
E.M.Hoey,
A.Trudgett,
and
D.J.Timson
(2007).
Characterisation of two calmodulin-like proteins from the liver fluke, Fasciola hepatica.
|
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Biol Chem,
388,
593-599.
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T.M.Lakowski,
G.M.Lee,
M.Okon,
R.E.Reid,
and
L.P.McIntosh
(2007).
Calcium-induced folding of a fragment of calmodulin composed of EF-hands 2 and 3.
|
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Protein Sci,
16,
1119-1132.
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PDB code:
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V.Vacic,
C.J.Oldfield,
A.Mohan,
P.Radivojac,
M.S.Cortese,
V.N.Uversky,
and
A.K.Dunker
(2007).
Characterization of molecular recognition features, MoRFs, and their binding partners.
|
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J Proteome Res,
6,
2351-2366.
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W.S.Jong,
C.M.ten Hagen-Jongman,
T.den Blaauwen,
D.J.Slotboom,
J.R.Tame,
D.Wickström,
J.W.de Gier,
B.R.Otto,
and
J.Luirink
(2007).
Limited tolerance towards folded elements during secretion of the autotransporter Hbp.
|
| |
Mol Microbiol,
63,
1524-1536.
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A.Ganoth,
E.Nachliel,
R.Friedman,
and
M.Gutman
(2006).
Molecular dynamics study of a calmodulin-like protein with an IQ peptide: spontaneous refolding of the protein around the peptide.
|
| |
Proteins,
64,
133-146.
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A.Houdusse,
J.F.Gaucher,
E.Krementsova,
S.Mui,
K.M.Trybus,
and
C.Cohen
(2006).
Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features.
|
| |
Proc Natl Acad Sci U S A,
103,
19326-19331.
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PDB code:
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C.K.Johnson
(2006).
Calmodulin, conformational states, and calcium signaling. A single-molecule perspective.
|
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Biochemistry,
45,
14233-14246.
|
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E.Babini,
I.Bertini,
F.Capozzi,
E.Chirivino,
and
C.Luchinat
(2006).
A structural and dynamic characterization of the EF-hand protein CLSP.
|
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Structure,
14,
1029-1038.
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PDB code:
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E.Lyman,
and
D.M.Zuckerman
(2006).
Ensemble-based convergence analysis of biomolecular trajectories.
|
| |
Biophys J,
91,
164-172.
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E.Project,
R.Friedman,
E.Nachliel,
and
M.Gutman
(2006).
A molecular dynamics study of the effect of Ca2+ removal on calmodulin structure.
|
| |
Biophys J,
90,
3842-3850.
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F.Capozzi,
F.Casadei,
and
C.Luchinat
(2006).
EF-hand protein dynamics and evolution of calcium signal transduction: an NMR view.
|
| |
J Biol Inorg Chem,
11,
949-962.
|
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J.M.Shifman,
M.H.Choi,
S.Mihalas,
S.L.Mayo,
and
M.B.Kennedy
(2006).
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums.
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| |
Proc Natl Acad Sci U S A,
103,
13968-13973.
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J.S.Salafsky
(2006).
Detection of protein conformational change by optical second-harmonic generation.
|
| |
J Chem Phys,
125,
074701.
|
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K.Chen,
J.Ruan,
and
L.A.Kurgan
(2006).
Prediction of three dimensional structure of calmodulin.
|
| |
Protein J,
25,
57-70.
|
|
|
|
|
|
|
L.Milanesi,
C.A.Hunter,
S.E.Sedelnikova,
and
J.P.Waltho
(2006).
Amplification of bifunctional ligands for calmodulin from a dynamic combinatorial library.
|
| |
Chemistry,
12,
1081-1087.
|
|
|
|
|
|
|
M.M.Wu,
J.Buchanan,
R.M.Luik,
and
R.S.Lewis
(2006).
Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane.
|
| |
J Cell Biol,
174,
803-813.
|
|
|
|
|
|
|
M.T.Naik,
N.Suree,
U.Ilangovan,
C.K.Liew,
W.Thieu,
D.O.Campbell,
J.J.Clemens,
M.E.Jung,
and
R.T.Clubb
(2006).
Staphylococcus aureus Sortase A transpeptidase. Calcium promotes sorting signal binding by altering the mobility and structure of an active site loop.
|
| |
J Biol Chem,
281,
1817-1826.
|
|
|
|
|
|
|
X.Zhang,
T.Zou,
Y.Liu,
and
Y.Qi
(2006).
The gating effect of calmodulin and calcium on the connexin50 hemichannel.
|
| |
Biol Chem,
387,
595-601.
|
|
|
|
|
|
|
Y.B.Ammar,
S.Takeda,
T.Hisamitsu,
H.Mori,
and
S.Wakabayashi
(2006).
Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation.
|
| |
EMBO J,
25,
2315-2325.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
A.A.Pandyra,
A.P.Yamniuk,
V.V.Andrushchenko,
H.Wieser,
and
H.J.Vogel
(2005).
Isotope-labeled vibrational circular dichroism studies of calmodulin and its interactions with ligands.
|
| |
Biopolymers,
79,
231-237.
|
|
|
|
|
|
|
C.L.Chyan,
P.C.Huang,
T.H.Lin,
J.W.Huang,
S.S.Lin,
H.B.Huang,
and
Y.C.Chen
(2005).
Purification, crystallization and preliminary crystallographic studies of a calmodulin-OLFp hybrid molecule.
|
| |
Acta Crystallogr Sect F Struct Biol Cryst Commun,
61,
785-787.
|
|
|
|
|
|
|
G.Fiorin,
R.R.Biekofsky,
A.Pastore,
and
P.Carloni
(2005).
Unwinding the helical linker of calcium-loaded calmodulin: a molecular dynamics study.
|
| |
Proteins,
61,
829-839.
|
|
|
|
|
|
|
I.Horváth,
V.Harmat,
A.Perczel,
V.Pálfi,
L.Nyitray,
A.Nagy,
E.Hlavanda,
G.Náray-Szabó,
and
J.Ovádi
(2005).
The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug.
|
| |
J Biol Chem,
280,
8266-8274.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
K.A.Young,
and
J.H.Caldwell
(2005).
Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin.
|
| |
J Physiol,
565,
349-370.
|
|
|
|
|
|
|
M.Palczewska,
G.Batta,
P.Groves,
S.Linse,
and
J.Kuznicki
(2005).
Characterization of calretinin I-II as an EF-hand, Ca2+, H+-sensing domain.
|
| |
Protein Sci,
14,
1879-1887.
|
|
|
|
|
|
|
N.Uchikoga,
S.Y.Takahashi,
R.Ke,
M.Sonoyama,
and
S.Mitaku
(2005).
Electric charge balance mechanism of extended soluble proteins.
|
| |
Protein Sci,
14,
74-80.
|
|
|
|
|
|
|
P.Lundström,
and
M.Akke
(2005).
Microsecond protein dynamics measured by 13Calpha rotating-frame spin relaxation.
|
| |
Chembiochem,
6,
1685-1692.
|
|
|
|
|
|
|
P.Lundström,
and
M.Akke
(2005).
Off-resonance rotating-frame amide proton spin relaxation experiments measuring microsecond chemical exchange in proteins.
|
| |
J Biomol NMR,
32,
163-173.
|
|
|
|
|
|
|
A.M.Weljie,
and
H.J.Vogel
(2004).
Unexpected structure of the Ca2+-regulatory region from soybean calcium-dependent protein kinase-alpha.
|
| |
J Biol Chem,
279,
35494-35502.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
A.P.Yamniuk,
and
H.J.Vogel
(2004).
Structurally homologous binding of plant calmodulin isoforms to the calmodulin-binding domain of vacuolar calcium-ATPase.
|
| |
J Biol Chem,
279,
7698-7707.
|
|
|
|
|
|
|
B.Bánfi,
F.Tirone,
I.Durussel,
J.Knisz,
P.Moskwa,
G.Z.Molnár,
K.H.Krause,
and
J.A.Cox
(2004).
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5).
|
| |
J Biol Chem,
279,
18583-18591.
|
|
|
|
|
|
|
B.Wang,
S.R.Martin,
R.A.Newman,
S.L.Hamilton,
M.A.Shea,
P.M.Bayley,
and
K.M.Beckingham
(2004).
Biochemical properties of V91G calmodulin: A calmodulin point mutation that deregulates muscle contraction in Drosophila.
|
| |
Protein Sci,
13,
3285-3297.
|
|
|
|
|
|
|
C.M.Shepherd,
and
H.J.Vogel
(2004).
A molecular dynamics study of Ca(2+)-calmodulin: evidence of interdomain coupling and structural collapse on the nanosecond timescale.
|
| |
Biophys J,
87,
780-791.
|
|
|
|
|
|
|
G.Qing,
L.C.Ma,
A.Khorchid,
G.V.Swapna,
T.K.Mal,
M.M.Takayama,
B.Xia,
S.Phadtare,
H.Ke,
T.Acton,
G.T.Montelione,
M.Ikura,
and
M.Inouye
(2004).
Cold-shock induced high-yield protein production in Escherichia coli.
|
| |
Nat Biotechnol,
22,
877-882.
|
|
|
|
|
|
|
H.Hu,
J.H.Sheehan,
and
W.J.Chazin
(2004).
The mode of action of centrin. Binding of Ca2+ and a peptide fragment of Kar1p to the C-terminal domain.
|
| |
J Biol Chem,
279,
50895-50903.
|
|
|
|
|
|
|
J.S.Shim,
J.Lee,
H.J.Park,
S.J.Park,
and
H.J.Kwon
(2004).
A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function.
|
| |
Chem Biol,
11,
1455-1463.
|
|
|
|
|
|
|
M.A.Schumacher,
M.Crum,
and
M.C.Miller
(2004).
Crystal structures of apocalmodulin and an apocalmodulin/SK potassium channel gating domain complex.
|
| |
Structure,
12,
849-860.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
W.Zhou,
Y.Qian,
K.Kunjilwar,
P.J.Pfaffinger,
and
S.Choe
(2004).
Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels.
|
| |
Neuron,
41,
573-586.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
A.M.Weljie,
A.P.Yamniuk,
H.Yoshino,
Y.Izumi,
and
H.J.Vogel
(2003).
Protein conformational changes studied by diffusion NMR spectroscopy: application to helix-loop-helix calcium binding proteins.
|
| |
Protein Sci,
12,
228-236.
|
|
|
|
|
|
|
A.M.Weljie,
K.M.Robertson,
and
H.J.Vogel
(2003).
Conformational changes in the Ca2+-regulatory region from soybean calcium-dependent protein kinase-alpha: fluorescence resonance energy transfer studies.
|
| |
J Biol Chem,
278,
43764-43769.
|
|
|
|
|
|
|
H.Tossavainen,
P.Permi,
A.Annila,
I.Kilpeläinen,
and
T.Drakenberg
(2003).
NMR solution structure of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea.
|
| |
Eur J Biochem,
270,
2505-2512.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
J.Kleinjung,
F.Fraternali,
S.R.Martin,
and
P.M.Bayley
(2003).
Thermal unfolding simulations of apo-calmodulin using leap-dynamics.
|
| |
Proteins,
50,
648-656.
|
|
|
|
|
|
|
J.Symersky,
G.Lin,
S.Li,
S.Qiu,
M.Carson,
N.Schormann,
and
M.Luo
(2003).
Structural genomics of caenorhabditis elegans: crystal structure of calmodulin.
|
| |
Proteins,
53,
947-949.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
M.Aoyagi,
A.S.Arvai,
J.A.Tainer,
and
E.D.Getzoff
(2003).
Structural basis for endothelial nitric oxide synthase binding to calmodulin.
|
| |
EMBO J,
22,
766-775.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
M.M.Zhu,
D.L.Rempel,
J.Zhao,
D.E.Giblin,
and
M.L.Gross
(2003).
Probing Ca2+-induced conformational changes in porcine calmodulin by H/D exchange and ESI-MS: effect of cations and ionic strength.
|
| |
Biochemistry,
42,
15388-15397.
|
|
|
|
|
|
|
M.Nagae,
A.Nozawa,
N.Koizumi,
H.Sano,
H.Hashimoto,
M.Sato,
and
T.Shimizu
(2003).
The crystal structure of the novel calcium-binding protein AtCBL2 from Arabidopsis thaliana.
|
| |
J Biol Chem,
278,
42240-42246.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
S.W.Vetter,
and
E.Leclerc
(2003).
Novel aspects of calmodulin target recognition and activation.
|
| |
Eur J Biochem,
270,
404-414.
|
|
|
|
|
|
|
V.Janssens,
J.Jordens,
I.Stevens,
C.Van Hoof,
E.Martens,
H.De Smedt,
Y.Engelborghs,
E.Waelkens,
and
J.Goris
(2003).
Identification and functional analysis of two Ca2+-binding EF-hand motifs in the B"/PR72 subunit of protein phosphatase 2A.
|
| |
J Biol Chem,
278,
10697-10706.
|
|
|
|
|
|
|
A.L.Papish,
L.W.Tari,
and
H.J.Vogel
(2002).
Dynamic light scattering study of calmodulin-target peptide complexes.
|
| |
Biophys J,
83,
1455-1464.
|
|
|
|
|
|
|
B.Wang,
C.Bolduc,
K.Beckingham,
K.Beckingham,
and
L.V.McIntire
(2002).
Calmodulin UAS-constructs and the in vivo roles of calmodulin: analysis of a muscle-specific phenotype.
|
| |
Genesis,
34,
86-90.
|
|
|
|
|
|
|
D.S.Libich,
and
G.Harauz
(2002).
Interactions of the 18.5-kDa isoform of myelin basic protein with Ca(2+)-calmodulin: in vitro studies using fluorescence microscopy and spectroscopy.
|
| |
Biochem Cell Biol,
80,
395-406.
|
|
|
|
|
|
|
G.Li,
and
Q.Cui
(2002).
A coarse-grained normal mode approach for macromolecules: an efficient implementation and application to Ca(2+)-ATPase.
|
| |
Biophys J,
83,
2457-2474.
|
|
|
|
|
|
|
J.B.Ames,
N.Hamasaki,
and
T.Molchanova
(2002).
Structure and calcium-binding studies of a recoverin mutant (E85Q) in an allosteric intermediate state.
|
| |
Biochemistry,
41,
5776-5787.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
J.Elezgaray,
G.Marcou,
and
Y.H.Sanejouand
(2002).
Exploring the natural conformational changes of the C-terminal domain of calmodulin.
|
| |
Phys Rev E Stat Nonlin Soft Matter Phys,
66,
031908.
|
|
|
|
|
|
|
J.K.Kranz,
E.K.Lee,
A.C.Nairn,
and
A.J.Wand
(2002).
A direct test of the reductionist approach to structural studies of calmodulin activity: relevance of peptide models of target proteins.
|
| |
J Biol Chem,
277,
16351-16354.
|
|
|
|
|
|
|
L.S.Mizoue,
and
W.J.Chazin
(2002).
Engineering and design of ligand-induced conformational change in proteins.
|
| |
Curr Opin Struct Biol,
12,
459-463.
|
|
|
|
|
|
|
M.R.Nelson,
E.Thulin,
P.A.Fagan,
S.Forsén,
and
W.J.Chazin
(2002).
The EF-hand domain: a globally cooperative structural unit.
|
| |
Protein Sci,
11,
198-205.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
R.R.Biekofsky,
S.R.Martin,
J.E.McCormick,
L.Masino,
S.Fefeu,
P.M.Bayley,
and
J.Feeney
(2002).
Thermal stability of calmodulin and mutants studied by (1)H-(15)N HSQC NMR measurements of selectively labeled [(15)N]Ile proteins.
|
| |
Biochemistry,
41,
6850-6859.
|
|
|
|
|
|
|
R.Wissmann,
W.Bildl,
H.Neumann,
A.F.Rivard,
N.Klöcker,
D.Weitz,
U.Schulte,
J.P.Adelman,
D.Bentrop,
and
B.Fakler
(2002).
A helical region in the C terminus of small-conductance Ca2+-activated K+ channels controls assembly with apo-calmodulin.
|
| |
J Biol Chem,
277,
4558-4564.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
S.R.Martin,
and
P.M.Bayley
(2002).
Regulatory implications of a novel mode of interaction of calmodulin with a double IQ-motif target sequence from murine dilute myosin V.
|
| |
Protein Sci,
11,
2909-2923.
|
|
|
|
|
|
|
W.E.Meador,
and
F.A.Quiocho
(2002).
Man bites dog.
|
| |
Nat Struct Biol,
9,
156-158.
|
|
|
|
|
|
|
A.Ababou,
and
J.R.Desjarlais
(2001).
Solvation energetics and conformational change in EF-hand proteins.
|
| |
Protein Sci,
10,
301-312.
|
|
|
|
|
|
|
D.Vigil,
S.C.Gallagher,
J.Trewhella,
and
A.E.García
(2001).
Functional dynamics of the hydrophobic cleft in the N-domain of calmodulin.
|
| |
Biophys J,
80,
2082-2092.
|
|
|
|
|
|
|
G.Larsson,
J.Schleucher,
J.Onions,
S.Hermann,
T.Grundström,
and
S.S.Wijmenga
(2001).
A novel target recognition revealed by calmodulin in complex with the basic helix--loop--helix transcription factor SEF2-1/E2-2.
|
| |
Protein Sci,
10,
169-186.
|
|
|
|
|
|
|
H.Aitio,
T.Laakso,
T.Pihlajamaa,
M.Torkkeli,
I.Kilpeläinen,
T.Drakenberg,
R.Serimaa,
and
A.Annila
(2001).
Characterization of apo and partially saturated states of calerythrin, an EF-hand protein from S. erythraea: a molten globule when deprived of Ca(2+).
|
| |
Protein Sci,
10,
74-82.
|
|
|
|
|
|
|
J.J.Chou,
S.Li,
C.B.Klee,
and
A.Bax
(2001).
Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains.
|
| |
Nat Struct Biol,
8,
990-997.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
M.Nakasako,
T.Fujisawa,
S.Adachi,
T.Kudo,
and
S.Higuchi
(2001).
Large-scale domain movements and hydration structure changes in the active-site cleft of unligated glutamate dehydrogenase from Thermococcus profundus studied by cryogenic X-ray crystal structure analysis and small-angle X-ray scattering.
|
| |
Biochemistry,
40,
3069-3079.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
S.S.Hook,
and
A.R.Means
(2001).
Ca(2+)/CaM-dependent kinases: from activation to function.
|
| |
Annu Rev Pharmacol Toxicol,
41,
471-505.
|
|
|
|
|
|
|
W.S.VanScyoc,
and
M.A.Shea
(2001).
Phenylalanine fluorescence studies of calcium binding to N-domain fragments of Paramecium calmodulin mutants show increased calcium affinity correlates with increased disorder.
|
| |
Protein Sci,
10,
1758-1768.
|
|
|
|
|
|
|
Z.Qin,
and
T.C.Squier
(2001).
Calcium-dependent stabilization of the central sequence between Met(76) and Ser(81) in vertebrate calmodulin.
|
| |
Biophys J,
81,
2908-2918.
|
|
|
|
|
|
|
A.Lewit-Bentley,
and
S.Réty
(2000).
EF-hand calcium-binding proteins.
|
| |
Curr Opin Struct Biol,
10,
637-643.
|
|
|
|
|
|
|
A.M.Weljie,
T.E.Clarke,
A.H.Juffer,
A.C.Harmon,
and
H.J.Vogel
(2000).
Comparative modeling studies of the calmodulin-like domain of calcium-dependent protein kinase from soybean.
|
| |
Proteins,
39,
343-357.
|
|
|
|
|
|
|
A.Ulrich,
A.A.Schmitz,
T.Braun,
T.Yuan,
H.J.Vogel,
and
G.Vergères
(2000).
Mapping the interface between calmodulin and MARCKS-related protein by fluorescence spectroscopy.
|
| |
Proc Natl Acad Sci U S A,
97,
5191-5196.
|
|
|
|
|
|
|
D.Yin,
H.Sun,
D.A.Ferrington,
and
T.C.Squier
(2000).
Closer proximity between opposing domains of vertebrate calmodulin following deletion of Met(145)-Lys(148).
|
| |
Biochemistry,
39,
10255-10268.
|
|
|
|
|
|
|
H.Ishida,
K.Takahashi,
K.Nakashima,
Y.Kumaki,
M.Nakata,
K.Hikichi,
and
M.Yazawa
(2000).
Solution structures of the N-terminal domain of yeast calmodulin: Ca2+-dependent conformational change and its functional implication.
|
| |
Biochemistry,
39,
13660-13668.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
H.Sun,
and
T.C.Squier
(2000).
Ordered and cooperative binding of opposing globular domains of calmodulin to the plasma membrane Ca-ATPase.
|
| |
J Biol Chem,
275,
1731-1738.
|
|
|
|
|
|
|
K.Palczewski,
A.S.Polans,
W.Baehr,
and
J.B.Ames
(2000).
Ca(2+)-binding proteins in the retina: structure, function, and the etiology of human visual diseases.
|
| |
Bioessays,
22,
337-350.
|
|
|
|
|
|
|
L.Masino,
S.R.Martin,
and
P.M.Bayley
(2000).
Ligand binding and thermodynamic stability of a multidomain protein, calmodulin.
|
| |
Protein Sci,
9,
1519-1529.
|
|
|
|
|
|
|
M.Mori,
T.Konno,
T.Ozawa,
M.Murata,
K.Imoto,
and
K.Nagayama
(2000).
Novel interaction of the voltage-dependent sodium channel (VDSC) with calmodulin: does VDSC acquire calmodulin-mediated Ca2+-sensitivity?
|
| |
Biochemistry,
39,
1316-1323.
|
|
|
|
|
|
|
R.D.Brokx,
and
H.J.Vogel
(2000).
Peptide and metal ion-dependent association of isolated helix-loop-helix calcium binding domains: studies of thrombic fragments of calmodulin.
|
| |
Protein Sci,
9,
964-975.
|
|
|
|
|
|
|
S.Fefeu,
R.R.Biekofsky,
J.E.McCormick,
S.R.Martin,
P.M.Bayley,
and
J.Feeney
(2000).
Calcium-induced refolding of the calmodulin V136G mutant studied by NMR spectroscopy: evidence for interaction between the two globular domains.
|
| |
Biochemistry,
39,
15920-15931.
|
|
|
|
|
|
|
S.R.Martin,
L.Masino,
and
P.M.Bayley
(2000).
Enhancement by Mg2+ of domain specificity in Ca2+-dependent interactions of calmodulin with target sequences.
|
| |
Protein Sci,
9,
2477-2488.
|
|
|
|
|
|
|
S.Y.Lee,
and
R.E.Klevit
(2000).
The whole is not the simple sum of its parts in calmodulin from S. cerevisiae.
|
| |
Biochemistry,
39,
4225-4230.
|
|
|
|
|
|
|
T.Berggård,
M.Silow,
E.Thulin,
and
S.Linse
(2000).
Ca(2+)- and H(+)-dependent conformational changes of calbindin D(28k).
|
| |
Biochemistry,
39,
6864-6873.
|
|
|
|
|
|
|
T.J.Hill,
D.Lafitte,
J.I.Wallace,
H.J.Cooper,
P.O.Tsvetkov,
and
P.J.Derrick
(2000).
Calmodulin-peptide interactions: apocalmodulin binding to the myosin light chain kinase target-site.
|
| |
Biochemistry,
39,
7284-7290.
|
|
|
|
|
|
|
T.Ozawa,
M.Fukuda,
M.Nara,
A.Nakamura,
Y.Komine,
K.Kohama,
and
Y.Umezawa
(2000).
How can Ca2+ selectively activate recoverin in the presence of Mg2+? Surface plasmon resonance and FT-IR spectroscopic studies.
|
| |
Biochemistry,
39,
14495-14503.
|
|
|
|
|
|
|
A.Wallqvist,
T.A.Lavoie,
J.A.Chanatry,
D.G.Covell,
and
J.Carey
(1999).
Cooperative folding units of escherichia coli tryptophan repressor.
|
| |
Biophys J,
77,
1619-1626.
|
|
|
|
|
|
|
D.Lafitte,
A.J.Heck,
T.J.Hill,
K.Jumel,
S.E.Harding,
and
P.J.Derrick
(1999).
Evidence of noncovalent dimerization of calmodulin.
|
| |
Eur J Biochem,
261,
337-344.
|
|
|
|
|
|
|
K.L.Yap,
J.B.Ames,
M.B.Swindells,
and
M.Ikura
(1999).
Diversity of conformational states and changes within the EF-hand protein superfamily.
|
| |
Proteins,
37,
499-507.
|
|
|
|
|
|
|
K.Nakashima,
H.Ishida,
S.Y.Ohki,
K.Hikichi,
and
M.Yazawa
(1999).
Calcium binding induces interaction between the N- and C-terminal domains of yeast calmodulin and modulates its overall conformation.
|
| |
Biochemistry,
38,
98.
|
|
|
|
|
|
|
K.W.Lo,
Q.Zhang,
M.Li,
and
M.Zhang
(1999).
Apoptosis-linked gene product ALG-2 is a new member of the calpain small subunit subfamily of Ca2+-binding proteins.
|
| |
Biochemistry,
38,
7498-7508.
|
|
|
|
|
|
|
O.Nemirovskiy,
D.E.Giblin,
and
M.L.Gross
(1999).
Electrospray ionization mass spectrometry and hydrogen/deuterium exchange for probing the interaction of calmodulin with calcium.
|
| |
J Am Soc Mass Spectrom,
10,
711-718.
|
|
|
|
|
|
|
S.B.Williams,
and
V.Stewart
(1999).
Functional similarities among two-component sensors and methyl-accepting chemotaxis proteins suggest a role for linker region amphipathic helices in transmembrane signal transduction.
|
| |
Mol Microbiol,
33,
1093-1102.
|
|
|
|
|
|
|
S.Rentschler,
H.Linn,
K.Deininger,
M.T.Bedford,
X.Espanel,
and
M.Sudol
(1999).
The WW domain of dystrophin requires EF-hands region to interact with beta-dystroglycan.
|
| |
Biol Chem,
380,
431-442.
|
|
|
|
|
|
|
T.Yuan,
and
H.J.Vogel
(1999).
Substitution of the methionine residues of calmodulin with the unnatural amino acid analogs ethionine and norleucine: biochemical and spectroscopic studies.
|
| |
Protein Sci,
8,
113-121.
|
|
|
|
|
|
|
T.Yuan,
H.Ouyang,
and
H.J.Vogel
(1999).
Surface exposure of the methionine side chains of calmodulin in solution. A nitroxide spin label and two-dimensional NMR study.
|
| |
J Biol Chem,
274,
8411-8420.
|
|
|
|
|
|
|
T.Yuan,
M.P.Walsh,
C.Sutherland,
H.Fabian,
and
H.J.Vogel
(1999).
Calcium-dependent and -independent interactions of the calmodulin-binding domain of cyclic nucleotide phosphodiesterase with calmodulin.
|
| |
Biochemistry,
38,
1446-1455.
|
|
|
|
|
|
|
A.L.Hazard,
S.C.Kohout,
N.L.Stricker,
J.A.Putkey,
and
J.J.Falke
(1998).
The kinetic cycle of cardiac troponin C: calcium binding and dissociation at site II trigger slow conformational rearrangements.
|
| |
Protein Sci,
7,
2451-2459.
|
|
|
|
|
|
|
A.Malmendal,
G.Carlstrom,
C.Hambraeus,
T.Drakenberg,
S.Forsen,
and
M.Akke
(1998).
Sequence and context dependence of EF-hand loop dynamics. An 15N relaxation study of a calcium-binding site mutant of calbindin D9k.
|
| |
Biochemistry,
37,
2586-2595.
|
|
|
|
|
|
|
A.Malmendal,
J.Evenäs,
E.Thulin,
G.P.Gippert,
T.Drakenberg,
and
S.Forsén
(1998).
When size is important. Accommodation of magnesium in a calcium binding regulatory domain.
|
| |
J Biol Chem,
273,
28994-29001.
|
|
|
|
|
|
|
J.Gao,
D.H.Yin,
Y.Yao,
H.Sun,
Z.Qin,
C.Schöneich,
T.D.Williams,
and
T.C.Squier
(1998).
Loss of conformational stability in calmodulin upon methionine oxidation.
|
| |
Biophys J,
74,
1115-1134.
|
|
|
|
|
|
|
J.K.Krueger,
N.A.Bishop,
D.K.Blumenthal,
G.Zhi,
K.Beckingham,
J.T.Stull,
and
J.Trewhella
(1998).
Calmodulin binding to myosin light chain kinase begins at substoichiometric Ca2+ concentrations: a small-angle scattering study of binding and conformational transitions.
|
| |
Biochemistry,
37,
17810-17817.
|
|
|
|
|
|
|
M.R.Nelson,
and
W.J.Chazin
(1998).
An interaction-based analysis of calcium-induced conformational changes in Ca2+ sensor proteins.
|
| |
Protein Sci,
7,
270-282.
|
|
|
|
|
|
|
M.Sastry,
R.R.Ketchem,
O.Crescenzi,
C.Weber,
M.J.Lubienski,
H.Hidaka,
and
W.J.Chazin
(1998).
The three-dimensional structure of Ca(2+)-bound calcyclin: implications for Ca(2+)-signal transduction by S100 proteins.
|
| |
Structure,
6,
223-231.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
R.E.Zielinski
(1998).
CALMODULIN AND CALMODULIN-BINDING PROTEINS IN PLANTS.
|
| |
Annu Rev Plant Physiol Plant Mol Biol,
49,
697-725.
|
|
|
|
|
|
|
R.Gilli,
D.Lafitte,
C.Lopez,
M.Kilhoffer,
A.Makarov,
C.Briand,
and
J.Haiech
(1998).
Thermodynamic analysis of calcium and magnesium binding to calmodulin.
|
| |
Biochemistry,
37,
5450-5456.
|
|
|
|
|
|
|
R.R.Biekofsky,
S.R.Martin,
J.P.Browne,
P.M.Bayley,
and
J.Feeney
(1998).
Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site Ca2+ coordination.
|
| |
Biochemistry,
37,
7617-7629.
|
|
|
|
|
|
|
S.P.Smith,
and
G.S.Shaw
(1998).
A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form.
|
| |
Structure,
6,
211-222.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
T.A.Millward,
C.W.Heizmann,
B.W.Schäfer,
and
B.A.Hemmings
(1998).
Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins.
|
| |
EMBO J,
17,
5913-5922.
|
|
|
|
|
|
|
T.Wolf,
B.Solomon,
D.Ivnitski,
J.Rishpon,
and
G.Fleminger
(1998).
Interactions of calmodulin with metal ions and with its target proteins revealed by conformation-sensitive monoclonal antibodies.
|
| |
J Mol Recognit,
11,
14-19.
|
|
|
|
|
|
|
T.Yuan,
A.M.Weljie,
and
H.J.Vogel
(1998).
Tryptophan fluorescence quenching by methionine and selenomethionine residues of calmodulin: orientation of peptide and protein binding.
|
| |
Biochemistry,
37,
3187-3195.
|
|
|
|
|
|
|
T.Yuan,
and
H.J.Vogel
(1998).
Calcium-calmodulin-induced dimerization of the carboxyl-terminal domain from petunia glutamate decarboxylase. A novel calmodulin-peptide interaction motif.
|
| |
J Biol Chem,
273,
30328-30335.
|
|
|
|
|
|
|
W.Wriggers,
E.Mehler,
F.Pitici,
H.Weinstein,
and
K.Schulten
(1998).
Structure and dynamics of calmodulin in solution.
|
| |
Biophys J,
74,
1622-1639.
|
|
|
|
|
|
|
X.Shao,
I.Fernandez,
T.C.Südhof,
and
J.Rizo
(1998).
Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?
|
| |
Biochemistry,
37,
16106-16115.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
C.H.Han,
and
D.M.Roberts
(1997).
Altered methylation substrate kinetics and calcium binding of a calmodulin with a Val136-->Thr substitution.
|
| |
Eur J Biochem,
244,
904-912.
|
|
|
|
|
|
|
D.Chin,
K.E.Winkler,
and
A.R.Means
(1997).
Characterization of substrate phosphorylation and use of calmodulin mutants to address implications from the enzyme crystal structure of calmodulin-dependent protein kinase I.
|
| |
J Biol Chem,
272,
31235-31240.
|
|
|
|
|
|
|
I.Protasevich,
B.Ranjbar,
V.Lobachov,
A.Makarov,
R.Gilli,
C.Briand,
D.Lafitte,
and
J.Haiech
(1997).
Conformation and thermal denaturation of apocalmodulin: role of electrostatic mutations.
|
| |
Biochemistry,
36,
2017-2024.
|
|
|
|
|
|
|
J.Evenäs,
E.Thulin,
A.Malmendal,
S.Forsén,
and
G.Carlström
(1997).
NMR studies of the E140Q mutant of the carboxy-terminal domain of calmodulin reveal global conformational exchange in the Ca2+-saturated state.
|
| |
Biochemistry,
36,
3448-3457.
|
|
|
|
|
|
|
J.K.Krueger,
G.A.Olah,
S.E.Rokop,
G.Zhi,
J.T.Stull,
and
J.Trewhella
(1997).
Structures of calmodulin and a functional myosin light chain kinase in the activated complex: a neutron scattering study.
|
| |
Biochemistry,
36,
6017-6023.
|
|
|
|
|
|
|
J.P.Browne,
M.Strom,
S.R.Martin,
and
P.M.Bayley
(1997).
The role of beta-sheet interactions in domain stability, folding, and target recognition reactions of calmodulin.
|
| |
Biochemistry,
36,
9550-9561.
|
|
|
|
|
|
|
L.Spyracopoulos,
M.X.Li,
S.K.Sia,
S.M.Gagné,
M.Chandra,
R.J.Solaro,
and
B.D.Sykes
(1997).
Calcium-induced structural transition in the regulatory domain of human cardiac troponin C.
|
| |
Biochemistry,
36,
12138-12146.
|
|
|
PDB codes:
|
|
|
|
|
|
|
|
O.B.Peersen,
T.S.Madsen,
and
J.J.Falke
(1997).
Intermolecular tuning of calmodulin by target peptides and proteins: differential effects on Ca2+ binding and implications for kinase activation.
|
| |
Protein Sci,
6,
794-807.
|
|
|
|
|
|
|
S.Linse,
E.Thulin,
L.K.Gifford,
D.Radzewsky,
J.Hagan,
R.R.Wilk,
and
K.S.Akerfeldt
(1997).
Domain organization of calbindin D28k as determined from the association of six synthetic EF-hand fragments.
|
| |
Protein Sci,
6,
2385-2396.
|
|
|
|
|
|
|
S.Lundberg,
A.V.Buevich,
I.Sethson,
U.Edlund,
and
L.Backman
(1997).
Calcium-binding mechanism of human nonerythroid alpha-spectrin EF-structures.
|
| |
Biochemistry,
36,
7199-7208.
|
|
|
|
|
|
|
S.M.Gagné,
M.X.Li,
and
B.D.Sykes
(1997).
Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins.
|
| |
Biochemistry,
36,
4386-4392.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
W.D.Kohn,
C.T.Mant,
and
R.S.Hodges
(1997).
Alpha-helical protein assembly motifs.
|
| |
J Biol Chem,
272,
2583-2586.
|
|
|
|
|
|
|
X.Wu,
and
R.E.Reid
(1997).
Conservative D133E mutation of calmodulin site IV drastically alters calcium binding and phosphodiesterase regulation.
|
| |
Biochemistry,
36,
3608-3616.
|
|
|
|
|
|
|
A.Houdusse,
M.Silver,
and
C.Cohen
(1996).
A model of Ca(2+)-free calmodulin binding to unconventional myosins reveals how calmodulin acts as a regulatory switch.
|
| |
Structure,
4,
1475-1490.
|
|
|
PDB code:
|
|
|
|
|
|
|
|
A.J.Wand,
and
S.W.Englander
(1996).
Protein complexes studied by NMR spectroscopy.
|
| |
Curr Opin Biotechnol,
7,
403-408.
|
|
|
|
|
|
|
B.C.Potts,
G.Carlström,
K.Okazaki,
H.Hidaka,
and
W.J.Chazin
(1996).
1H NMR assignments of apo calcyclin and comparative structural analysis with calbindin D9k and S100 beta.
|
| |
Protein Sci,
5,
2162-2174.
|
|
|
|
|
|
|
B.R.Sorensen,
and
M.A.Shea
(1996).
Calcium binding decreases the stokes radius of calmodulin and mutants R74A, R90A, and R90G.
|
| |
Biophys J,
71,
3407-3420.
|
|
|
|
|
|
|
D.F.Meyer,
Y.Mabuchi,
and
Z.Grabarek
(1996).
The role of Phe-92 in the Ca(2+)-induced conformational transition in the C-terminal domain of calmodulin.
|
| |
J Biol Chem,
271,
11284-11290.
|
|
|
|
|
|
|
D.van der Spoel,
B.L.de Groot,
S.Hayward,
H.J.Berendsen,
and
H.J.Vogel
(1996).
Bending of the calmodulin central helix: a theoretical study.
|
| |
Protein Sci,
5,
2044-2053.
|
|
|
|
|
|
|
K.S.Akerfeldt,
A.N.Coyne,
R.R.Wilk,
E.Thulin,
and
S.Linse
(1996).
Ca2+-binding stoichiometry of calbindin D28k as assessed by spectroscopic analyses of synthetic peptide fragments.
|
| |
Biochemistry,
35,
3662-3669.
|
|
|
|
|
|
|
M.Ikura
(1996).
Calcium binding and conformational response in EF-hand proteins.
|
| |
Trends Biochem Sci,
21,
14-17.
|
|
|
|
|
|
|
P.M.Bayley,
W.A.Findlay,
and
S.R.Martin
(1996).
Target recognition by calmodulin: dissecting the kinetics and affinity of interaction using short peptide sequences.
|
| |
Protein Sci,
5,
1215-1228.
|
|
|
|
|
|
|
P.Mukherjea,
J.F.Maune,
and
K.Beckingham
(1996).
Interlobe communication in multiple calcium-binding site mutants of Drosophila calmodulin.
|
| |
Protein Sci,
5,
468-477.
|
|
|
|
|
|
|
S.P.Smith,
K.R.Barber,
S.D.Dunn,
and
G.S.Shaw
(1996).
Structural influence of cation binding to recombinant human brain S100b: evidence for calcium-induced exposure of a hydrophobic surface.
|
| |
Biochemistry,
35,
8805-8814.
|
|
|
|
|
|
|
S.R.Martin,
P.M.Bayley,
S.E.Brown,
T.Porumb,
M.Zhang,
and
M.Ikura
(1996).
Spectroscopic characterization of a high-affinity calmodulin-target peptide hybrid molecule.
|
| |
Biochemistry,
35,
3508-3517.
|
|
|
|
|
|
|
S.M.Gagné,
S.Tsuda,
M.X.Li,
L.B.Smillie,
and
B.D.Sykes
(1995).
Structures of the troponin C regulatory domains in the apo and calcium-saturated states.
|
| |
Nat Struct Biol,
2,
784-789.
|
|
|
PDB codes:
|
|
|
|
|
|
|
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Where a reference describes a PDB structure, the PDB
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