Literature references that cite this PDB file's
key reference
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PubMed id
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Reference
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Z.Shmelzer,
M.Karter,
M.Eisenstein,
T.L.Leto,
N.Hadad,
D.Ben-Menahem,
D.Gitler,
S.Banani,
B.Wolach,
M.Rotem,
and
R.Levy
(2008).
Cytosolic Phospholipase A2{alpha} Is Targeted to the p47phox-PX Domain of the Assembled NADPH Oxidase via a Novel Binding Site in Its C2 Domain.
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J Biol Chem, 283,
31898-31908.
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A.Abyzov,
and
V.A.Ilyin
(2007).
A comprehensive analysis of non-sequential alignments between all protein structures.
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BMC Struct Biol, 7,
78.
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G.Drin,
and
S.Scarlata
(2007).
Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme?
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Cell Signal, 19,
1383-1392.
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J.L.Jiménez,
and
B.Davletov
(2007).
Beta-strand recombination in tricalbin evolution and the origin of synaptotagmin-like C2 domains.
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Proteins, 68,
770-778.
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S.Varma,
and
E.Jakobsson
(2007).
The cPLA2 C2alpha domain in solution: structure and dynamics of its Ca2+-activated and cation-free states.
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Biophys J, 92,
966-976.
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C.Malcuit,
M.Kurokawa,
and
R.A.Fissore
(2006).
Calcium oscillations and mammalian egg activation.
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J Cell Physiol, 206,
565-573.
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T.K.Harden,
and
J.Sondek
(2006).
Regulation of phospholipase C isozymes by ras superfamily GTPases.
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Annu Rev Pharmacol Toxicol, 46,
355-379.
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I.Voskoboinik,
M.C.Thia,
J.Fletcher,
A.Ciccone,
K.Browne,
M.J.Smyth,
and
J.A.Trapani
(2005).
Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.
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J Biol Chem, 280,
8426-8434.
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O.H.Shin,
W.Han,
Y.Wang,
and
T.C.Südhof
(2005).
Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties.
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J Biol Chem, 280,
1641-1651.
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S.Málková,
F.Long,
R.V.Stahelin,
S.V.Pingali,
D.Murray,
W.Cho,
and
M.L.Schlossman
(2005).
X-ray reflectivity studies of cPLA2{alpha}-C2 domains adsorbed onto Langmuir monolayers of SOPC.
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Biophys J, 89,
1861-1873.
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W.Cho,
and
R.V.Stahelin
(2005).
Membrane-protein interactions in cell signaling and membrane trafficking.
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Annu Rev Biophys Biomol Struct, 34,
119-151.
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B.Davletov,
and
J.L.Jiménez
(2004).
Sculpting a domain by splicing.
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Nat Struct Mol Biol, 11,
4-5.
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J.Garcia,
S.H.Gerber,
S.Sugita,
T.C.Südhof,
and
J.Rizo
(2004).
A conformational switch in the Piccolo C2A domain regulated by alternative splicing.
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Nat Struct Mol Biol, 11,
45-53.
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PDB code:
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T.Sklyarova,
V.De Corte,
K.Meerschaert,
L.Devriendt,
B.Vanloo,
J.Bailey,
L.J.Cook,
M.Goethals,
J.Van Damme,
M.Puype,
J.Vandekerckhove,
and
J.Gettemans
(2002).
Fragmin60 encodes an actin-binding protein with a C2 domain and controls actin Thr-203 phosphorylation in Physarum plasmodia and sclerotia.
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J Biol Chem, 277,
39840-39849.
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B.Vanhaesebroeck,
S.J.Leevers,
K.Ahmadi,
J.Timms,
R.Katso,
P.C.Driscoll,
R.Woscholski,
P.J.Parker,
and
M.D.Waterfield
(2001).
Synthesis and function of 3-phosphorylated inositol lipids.
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Annu Rev Biochem, 70,
535-602.
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S.G.Rhee
(2001).
Regulation of phosphoinositide-specific phospholipase C.
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Annu Rev Biochem, 70,
281-312.
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S.H.Gerber,
J.Garcia,
J.Rizo,
and
T.C.Südhof
(2001).
An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release.
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EMBO J, 20,
1605-1619.
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J.H.Hurley,
and
S.Misra
(2000).
Signaling and subcellular targeting by membrane-binding domains.
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Annu Rev Biophys Biomol Struct, 29,
49-79.
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R.A.García,
C.E.Forde,
and
H.A.Godwin
(2000).
Calcium triggers an intramolecular association of the C2 domains in synaptotagmin.
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Proc Natl Acad Sci U S A, 97,
5883-5888.
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J.W.Lomasney,
H.F.Cheng,
S.R.Roffler,
and
K.King
(1999).
Activation of phospholipase C delta1 through C2 domain by a Ca(2+)-enzyme-phosphatidylserine ternary complex.
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J Biol Chem, 274,
21995-22001.
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M.Yamaga,
M.Fujii,
H.Kamata,
H.Hirata,
and
H.Yagisawa
(1999).
Phospholipase C-delta1 contains a functional nuclear export signal sequence.
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J Biol Chem, 274,
28537-28541.
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N.Verdaguer,
S.Corbalan-Garcia,
W.F.Ochoa,
I.Fita,
and
J.C.Gómez-Fernández
(1999).
Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.
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EMBO J, 18,
6329-6338.
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PDB code:
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O.Perisic,
H.F.Paterson,
G.Mosedale,
S.Lara-González,
and
R.L.Williams
(1999).
Mapping the phospholipid-binding surface and translocation determinants of the C2 domain from cytosolic phospholipase A2.
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J Biol Chem, 274,
14979-14987.
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R.B.Sutton,
J.A.Ernst,
and
A.T.Brunger
(1999).
Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca(+2)-independent snare complex interaction.
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J Cell Biol, 147,
589-598.
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PDB code:
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S.J.Slater,
S.K.Milano,
B.A.Stagliano,
K.J.Gergich,
C.Ho,
A.Mazurek,
F.J.Taddeo,
M.B.Kelly,
M.D.Yeager,
and
C.D.Stubbs
(1999).
Synergistic activation of protein kinase Calpha, -betaI, and -gamma isoforms induced by diacylglycerol and phorbol ester: roles of membrane association and activating conformational changes.
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Biochemistry, 38,
3804-3815.
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T.Pawelczyk,
and
A.Matecki
(1999).
Phospholipase C-delta3 binds with high specificity to phosphatidylinositol 4,5-bisphosphate and phosphatidic acid in bilayer membranes.
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Eur J Biochem, 262,
291-298.
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A.Arcaro,
S.Volinia,
M.J.Zvelebil,
R.Stein,
S.J.Watton,
M.J.Layton,
I.Gout,
K.Ahmadi,
J.Downward,
and
M.D.Waterfield
(1998).
Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity.
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J Biol Chem, 273,
33082-33090.
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B.Davletov,
O.Perisic,
and
R.L.Williams
(1998).
Calcium-dependent membrane penetration is a hallmark of the C2 domain of cytosolic phospholipase A2 whereas the C2A domain of synaptotagmin binds membranes electrostatically.
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J Biol Chem, 273,
19093-19096.
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C.E.Naylor,
J.T.Eaton,
A.Howells,
N.Justin,
D.S.Moss,
R.W.Titball,
and
A.K.Basak
(1998).
Structure of the key toxin in gas gangrene.
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Nat Struct Biol, 5,
738-746.
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PDB code:
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E.A.Nalefski,
and
J.J.Falke
(1998).
Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A2.
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Biochemistry, 37,
17642-17650.
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E.R.Chapman,
and
A.F.Davis
(1998).
Direct interaction of a Ca2+-binding loop of synaptotagmin with lipid bilayers.
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J Biol Chem, 273,
13995-14001.
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J.A.Grobler,
and
J.H.Hurley
(1998).
Catalysis by phospholipase C delta1 requires that Ca2+ bind to the catalytic domain, but not the C2 domain.
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Biochemistry, 37,
5020-5028.
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J.Rizo,
and
T.C.Südhof
(1998).
C2-domains, structure and function of a universal Ca2+-binding domain.
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J Biol Chem, 273,
15879-15882.
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J.Ubach,
X.Zhang,
X.Shao,
T.C.Südhof,
and
J.Rizo
(1998).
Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain?
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EMBO J, 17,
3921-3930.
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O.Perisic,
S.Fong,
D.E.Lynch,
M.Bycroft,
and
R.L.Williams
(1998).
Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2.
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J Biol Chem, 273,
1596-1604.
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PDB code:
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S.Hayashizaki,
Y.Iino,
and
M.Yamamoto
(1998).
Characterization of the C. elegans gap-2 gene encoding a novel Ras-GTPase activating protein and its possible role in larval development.
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Genes Cells, 3,
189-202.
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X.Shao,
I.Fernandez,
T.C.Südhof,
and
J.Rizo
(1998).
Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?
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Biochemistry, 37,
16106-16115.
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PDB code:
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X.Zhang,
J.Rizo,
and
T.C.Südhof
(1998).
Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I.
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Biochemistry, 37,
12395-12403.
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Y.K.Chae,
F.Abildgaard,
E.R.Chapman,
and
J.L.Markley
(1998).
Lipid binding ridge on loops 2 and 3 of the C2A domain of synaptotagmin I as revealed by NMR spectroscopy.
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J Biol Chem, 273,
25659-25663.
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E.A.Nalefski,
M.M.Slazas,
and
J.J.Falke
(1997).
Ca2+-signaling cycle of a membrane-docking C2 domain.
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Biochemistry, 36,
12011-12018.
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R.Uellner,
M.J.Zvelebil,
J.Hopkins,
J.Jones,
L.K.MacDougall,
B.P.Morgan,
E.Podack,
M.D.Waterfield,
and
G.M.Griffiths
(1997).
Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.
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EMBO J, 16,
7287-7296.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
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so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
code is
shown on the right.
|
513 a.a.
559 a.a.
_CA
