PDBsum entry: 1cg9

Mhc class i

PDB id: 1cg9

Contents

Protein chains

277 a.a. *

100 a.a. *

Ligands

LEU-PRO-PRO-LEU-ASP-ILE-THR-PRO-TYR

Waters ×115

* Residue conservation analysis

PDB id:

1cg9

Name:

Mhc class i

Title:

Complex recognition of the supertypic bw6-determinant on hla-b and-c molecules by the monoclonal antibody sfr8-b6

Structure:

Protein (hla class i histocompatibility antigen, b-35 b 3501 Alpha chain). Chain: a. Engineered: yes. Mutation: yes. Protein (beta-2-microglobulin). Chain: b. Engineered: yes. Protein (ebna-6 nuclear protein (ebna-3c) (ebna-

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: synthetic gene. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide is found in the epstein-barr

Biol. unit:

Trimer (from PQS)

Resolution:

2.70Å R-factor: 0.201 R-free: 0.253

Authors:

R.Menssen,P.Orth,A.Ziegler,W.Saenger

Key ref:

R.Menssen et al. Complex recognition of the supertypic bw6-Determinant on hla-B and-C molecules by the monoclonal antibody sfr8-B6. To be published,

Date:

25-Mar-99 Release date: 18-Nov-03

Protein chain

P30685  (1B35_HUMAN) -  HLA class I histocompatibility antigen, B-35 alpha chain

Seq: 362 a.a.

Struc: 277 a.a.*

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin

Seq: 119 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 

• Cellular component: extracellular region (8 terms)
• Biological process: immune response (8 terms)
• Biochemical function: protein binding (1 term)