PDBsum entry: 1bb4

Hydrolase

PDB id: 1bb4

Contents

Protein chains

130 a.a. *

Waters ×243

* Residue conservation analysis

PDB id:

1bb4

Name:

Hydrolase

Title:

Human lysozyme double mutant a96l, w109h

Structure:

Lysozyme. Chain: a, b. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: pichia pastoris. Expression_system_taxid: 4922

Resolution:

2.23Å R-factor: 0.249 R-free: 0.290

Authors:

A.G.Headley,S.M.Roe,L.H.Pearl

Date:

28-Apr-98 Release date: 12-Aug-98

Protein chains

P61626  (LYSC_HUMAN) -  Lysozyme C

Seq: 148 a.a.

Struc: 130 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.2.1.17 - Lysozyme.
• Reaction: Hydrolysis of the 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid in peptidoglycan heteropolymers of the prokaryotes cell walls.

 Gene Ontology (GO) functional annotation 

• Cellular component: extracellular region (2 terms)
• Biological process: metabolic process (5 terms)
• Biochemical function: catalytic activity (5 terms)