PDBsum entry: 1am6

Hydrolase

PDB id: 1am6

Contents

Protein chain

258 a.a. *

Ligands

HAE

Metals

_HG

_ZN

Waters ×113

* Residue conservation analysis

PDB id:

1am6

Name:

Hydrolase

Title:

Carbonic anhydrase ii inhibitor: acetohydroxamate

Structure:

Carbonic anhydrase. Chain: a. Ec: 4.2.1.1

Source:

Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm

Resolution:

2.00Å R-factor: 0.160 R-free: 0.220

Authors:

L.R.Scolnick,A.M.Clements,D.W.Christianson

Key ref:

L.R.Scolnick et al. (1997). Novel binding mode of hydroxamate inhibitors to human carbonic anhydrase ii. J.Am.Chem.Soc., 119, PubMed id: -1

Date:

24-Jun-97 Release date: 24-Jun-98

Protein chain

P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2

Seq: 260 a.a.

Struc: 258 a.a.

Enzyme reactions

• Enzyme class: E.C.4.2.1.1 - Carbonate dehydratase.
• Reaction: H₂CO₃ = CO₂ + H₂O
• Cofactor: Zinc

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 Gene Ontology (GO) functional annotation 

• Cellular component: extracellular space (8 terms)
• Biological process: response to stress (15 terms)
• Biochemical function: protein binding (5 terms)