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PDBsum entry 1am6

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protein ligands metals links
Hydrolase PDB id
1am6
Jmol
Contents
Protein chain
258 a.a. *
Ligands
HAE
Metals
_HG
_ZN
Waters ×113
* Residue conservation analysis
PDB id:
1am6
Name: Hydrolase
Title: Carbonic anhydrase ii inhibitor: acetohydroxamate
Structure: Carbonic anhydrase. Chain: a. Ec: 4.2.1.1
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Resolution:
2.00Å     R-factor:   0.160     R-free:   0.220
Authors: L.R.Scolnick,A.M.Clements,D.W.Christianson
Key ref: L.R.Scolnick et al. (1997). Novel binding mode of hydroxamate inhibitors to human carbonic anhydrase ii. J.Am.Chem.Soc., 119, 850.
Date:
24-Jun-97     Release date:   24-Jun-98    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2
Seq:
Struc:
260 a.a.
258 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.4.2.1.1  - Carbonate dehydratase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: H2CO3 = CO2 + H2O
H(2)CO(3)
= CO(2)
+ H(2)O
      Cofactor: Zn(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular space   11 terms 
  Biological process     angiotensin-mediated signaling pathway   21 terms 
  Biochemical function     protein binding     5 terms