PDBsum entry: 1a7q

Immunoglobulin

PDB id: 1a7q

Contents

Protein chains

106 a.a. *

116 a.a. *

Waters ×47

* Residue conservation analysis

PDB id:

1a7q

Name:

Immunoglobulin

Title:

Fv fragment of mouse monoclonal antibody d1.3 (balb/c, igg1, k) high affinity expressed variant containing ser26l->gly, ile29l->thr, glu81l->asp, thr97l->ser, pro240h->leu, asp258h->ala, lys281h->glu, asn283h->asp and leu312h->val

Structure:

Igg1-kappa d1.3 fv (light chain). Chain: l. Fragment: fv fragment. Engineered: yes. Mutation: yes. Igg1-kappa d1.3 fv (heavy chain). Chain: h. Fragment: fv fragment. Engineered: yes.

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Variant: chain l, s26g, i29t, e81d, t97s, chain h, p240l, d258a, k281e, n283d, l312v. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562

Biol. unit:

Dimer (from PQS)

Resolution:

2.00Å R-factor: 0.178

Authors:

C.Marks,K.Henrick,G.Winter

Key ref:

C.Marks et al. X-Ray structures of d1.3 fv mutants. To be published,

Date:

16-Mar-98 Release date: 29-Apr-98