PDBsum entry: 1a7o

Immunoglobulin

PDB id: 1a7o

Contents

Protein chains

106 a.a. *

116 a.a. *

Waters ×132

* Residue conservation analysis

PDB id:

1a7o

Name:

Immunoglobulin

Title:

Fv fragment of mouse monoclonal antibody d1.3 (balb/c, igg1, k) r96l deletion mutant on variant for chain l glu81->asp and chain h leu312->val

Structure:

Igg1-kappa d1.3 fv (light chain). Chain: l. Fragment: fv fragment. Engineered: yes. Mutation: yes. Igg1-kappa d1.3 fv (heavy chain). Chain: h. Fragment: fv fragment. Engineered: yes.

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Variant: chain l, e81d, chain h, l312v. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562

Biol. unit:

Dimer (from PQS)

Resolution:

2.00Å R-factor: 0.167

Authors:

C.Marks,K.Henrick,G.Winter

Key ref:

C.Marks et al. X-Ray structures of d1.3 fv mutants. To be published,

Date:

16-Mar-98 Release date: 29-Apr-98

Protein chain

P01635  (KV5A3_MOUSE) -  Ig kappa chain V-V region K2 (Fragment)

Seq: 115 a.a.

Struc: 106 a.a.*

Protein chain

P01820  (HVM44_MOUSE) -  Ig heavy chain V region PJ14

Seq: 115 a.a.

Struc: 116 a.a.*

* PDB and UniProt seqs differ at 9 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 

• Biochemical function: antigen binding (2 terms)