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Hydrolase PDB-id
1zy9
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Protein chain
526 a.a. *
Ligands
EDO ×4
GOL
Waters ×244

* Residue conservation analysis
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PDB id: 1zy9
Name: Hydrolase
Title: Crystal structure of alpha-galactosidase (ec 3.2.1.22) (melibiase) (tm1192) from thermotoga maritima at 2.34 a resolution

Structure:
Alpha-galactosidase. Chain: a. Engineered: yes

Source:
Thermotoga maritima. Organism_taxid: 2336. Gene: tm1192. Expressed in: escherichia coli. Expression_system_taxid: 562.

UniProt:
O33835 (O33835_THEMA) Pfam  
Seq:
Struc:
Seq:
Struc:
Seq: 552 a.a.
Struc: 526 a.a.
Key:    PfamB domain  Secondary structure

Enzyme class:
E.C.3.2.1.22   [IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

Reaction:
Melibiose + H2O = galactose + glucose (see diagram below)

Cofactor:
Magnesium; NAD

Resolution:
2.34Å

R-factor:
0.162

R-free:
0.213

Authors:
Joint Center For Structural Genomics (Jcsg)

Key ref:
joint center for structural genomics (jcsg) Crystal structure of alpha-galactosidase (ec 3.2.1.22) (melibiase) (tm1192) from Thermotoga maritima at 2.34 A resolution. to be published, xsi:nil="true" />.

Date:
09-Jun-05

Release date:
12-Jul-05

Related entries:
283057 related db: targetdb
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Enzyme reaction for E.C.3.2.1.22


Melibiose
+ H(2)O
=
galactose
+
glucose
Cofactor

Magnesium

NAD
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.