PDBsum entry: 1yvw

Hydrolase

PDB-id: 1yvw

Biological unit* = asymmetric unit,
as shown
(*as deduced by PQS)

Contents

Description

Header details

Header records

References

PROCHECK

Protein chains

92 a.a. *

Waters ×169

* Residue conservation analysis

Tools

Clefts Calculation

PDB id:

1yvw

Name:

Hydrolase

Title:

Crystal structure of phosphoribosyl-atp pyrophosphohydrolase from bacillus cereus. Nesgc target bcr13.

Structure:

Phosphoribosyl-atp pyrophosphatase. Chain: a, b, c, d. Synonym: pra-ph. Engineered: yes

Source:

Bacillus cereus. Organism_taxid: 1396. Atcc: 14579. Gene: hise. Expressed in: escherichia coli. Expression_system_taxid: 562

Biological unit:

Tetramer (from PQS)

UniProt:

Chains A, B, C, D: Q81G00 (HIS2_BACCR)

Seq:

107 a.a.

Struc:

92 a.a.

Key:	PfamA domain
Secondary structure	CATH domain

Enzyme class:

E.C.3.6.1.31   [IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

Reaction:

1-(5-phosphoribosyl)-ATP + H₂O = 1-(5-phosphoribosyl)-AMP + diphosphate (see diagram below)

Pathway:

Histidine Biosynthesis (early stages)

Resolution:

2.60Å

R-factor:

0.244

R-free:

0.263

Authors:

J.Benach,A.P.Kuzin,F.Forouhar,M.Abashidze,S.M.Vorobiev, R.Shastry,X.Rong,T.B.Acton,G.T.Montelione,J.F.Hunt, Northeast Structural Genomics Consortium (Nesg)

Key ref:

j.benach et al. Crystal structure of Phosphoribosyl-ATP pyrophosphohydrolase from Bacillus cereus at 2.6 A resolution.. To be Published, xsi:nil="true" />.

Date:

16-Feb-05

Release date:

01-Mar-05

Related entries:

Bcr13 related db: targetdb

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