PDBsum entry: 1oj8

Hydrolase

PDB id: 1oj8

Contents

Protein chain

105 a.a. *

DNA/RNA

Ligands

SO4 ×2

Waters ×220

* Residue conservation analysis

PDB id:

1oj8

Name:

Hydrolase

Title:

Novel and retro binding modes in cytotoxic ribonucleases from rana catesbeiana of two crystal structures complexed with d(apcpgpa) and (2',5'cpg)

Structure:

Rc-rnase6 ribonuclease. Chain: a. Synonym: ribonuclease. 5'-d( Ap Cp Gp Ap)-3'. Chain: b

Source:

Rana catesbeiana. Bull frog. Organism_taxid: 8400. Atcc: aag31442. Tissue: occyte. Synthetic: yes

Biol. unit:

Dimer (from PDB file)

Resolution:

1.70Å R-factor: 0.229 R-free: 0.273

Authors:

C.-J.Tsai,J.-H.Liu,Y.-D.Liao,L.-Y.Chen,P.-T.Cheng,Y.-J.Sun

Key ref:

C.-J.Tsai et al. Retro and novel binding modes in cytotoxic ribonucleases from rana catesbeiana of two crystal structures complexed with (2',5'Cpg) and d(apcpgpa). To be published,

Date:

07-Jul-03 Release date: 15-Jul-04

Protein chain

Q9DFY5  (Q9DFY5_RANCA) -  RC-RNase6 ribonuclease (Precursor)

Seq: 128 a.a.

Struc: 105 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 

• Biochemical function: nucleic acid binding (2 terms)