OLDERADO

OLDERADO cluster and domain composition for PDB entry 2KJ3

High-resolution structure of the HET-s(218-289) prion in its amyloid form obtained by solid-state NMR
Summary of Olderado results
Most representative model 13
Largest domain comprises residues B.225-B.229, B.261-B.271, C.225-C.236, C.263-C.271
RMSD of all models in ensemble (Cα atoms) 5.7 Å

Protein domains shown as surfaces Representative models from each cluster
View in 3D View in 3D

Domain composition (NMRCore)
Domain number and colour code Residues Core Cumulative core
1 B.225-B.229, B.261-B.271, C.225-C.236, C.263-C.271 26.8 % 26.8 %
2 A.225-A.235, A.261-A.271, B.230-B.234 19.6 % 46.4 %
3 B.273-B.279, C.237-C.246, C.273-C.281 18.8 % 65.2 %
4 A.236-A.242, A.273-A.279, B.235-B.240 14.5 % 79.7 %
5 A.243-A.246, A.280-A.281, B.241-B.247, B.280-B.281 10.9 % 90.6 %
6 A.247-A.249, B.248-B.249 3.6 % 94.2 %
7 C.247-C.249 2.2 % 96.4 %
8 C.260-C.262 2.2 % 98.5 %
9 C.222-C.223 1.4 % 100.0 %

Cluster identification (NMRClust)
Cluster number and colour code Representative Members
1 13 1, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 17, 18, 19
2 6 2, 6, 15
3 16 5, 16
 
List of outliers (subfamily with one member): 20