PDBe 9pai

X-ray diffraction
2.7Å resolution

CLEAVED SUBSTRATE VARIANT OF PLASMINOGEN ACTIVATOR INHIBITOR-1

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plasminogen activator inhibitor 1 Chain: A
Molecule details ›
Chain: A
Length: 346 amino acids
Theoretical weight: 39.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05121 (Residues: 24-369; Coverage: 91%)
Gene names: PAI1, PLANH1, SERPINE1
Structure domains:
Plasminogen activator inhibitor 1 Chain: B
Molecule details ›
Chain: B
Length: 33 amino acids
Theoretical weight: 3.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05121 (Residues: 370-402; Coverage: 9%)
Gene names: PAI1, PLANH1, SERPINE1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS
Spacegroup: C2
Unit cell:
a: 151.86Å b: 47.52Å c: 62.73Å
α: 90° β: 113.95° γ: 90°
R-values:
R R work R free
0.181 0.181 0.295
Expression system: Escherichia coli