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Structure of phospho-Parkin bound to phospho-ubiquitin

Source organism: Homo sapiens
Biochemical function: zinc ion binding
Biological process: not assigned
Cellular component: cytosol

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EC 2.3.2.31: RBR-type E3 ubiquitin transferase

Reaction catalysed:
(1a) [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [RBR-type E3 ubiquitin transferase]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [RBR-type E3 ubiquitin transferase]-S-ubiquitinyl-L-cysteine
Systematic name:
S-ubiquitinyl-[ubiquitin-conjugating E2 enzyme]-L-cysteine:acceptor protein ubiquitin transferase (isopeptide bond-forming; RBR-type)

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00240
Domain description: Ubiquitin family
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
  2. Ubiquitin
The deposited structure of PDB entry 6glc contains 1 copy of Pfam domain PF00240 (Ubiquitin family) in E3 ubiquitin-protein ligase parkin. Showing 1 copy in chain A.
The deposited structure of PDB entry 6glc contains 1 copy of Pfam domain PF00240 (Ubiquitin family) in Ubiquitin. Showing 1 copy in chain B.

PF17978
Domain description: RING/Ubox like zinc-binding domain
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
The deposited structure of PDB entry 6glc contains 1 copy of Pfam domain PF17978 (RING/Ubox like zinc-binding domain) in E3 ubiquitin-protein ligase parkin. Showing 1 copy in chain A.

PF17976
Domain description: RING/Ubox like zinc-binding domain
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
The deposited structure of PDB entry 6glc contains 1 copy of Pfam domain PF17976 (RING/Ubox like zinc-binding domain) in E3 ubiquitin-protein ligase parkin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003977
Domain description: E3 ubiquitin-protein ligase parkin
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
IPR000626
Domain description: Ubiquitin-like domain
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
  2. Ubiquitin
IPR019956
Domain description: Ubiquitin domain
Occurring in:
  1. Ubiquitin
IPR029071
Domain description: Ubiquitin-like domain superfamily
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
  2. Ubiquitin
IPR019954
Domain description: Ubiquitin conserved site
Occurring in:
  1. Ubiquitin
IPR002867
Domain description: IBR domain
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
IPR047534
Domain description: E3 ubiquitin-protein ligase parkin, BRcat domain
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
IPR047535
Domain description: E3 ubiquitin-protein ligase parkin, RING finger, HC subclass
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
IPR044066
Domain description: TRIAD supradomain
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
IPR041170
Domain description: RING/Ubox-like zinc-binding domain
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
IPR041565
Domain description: Parkin, RING/Ubox like zinc-binding domain
Occurring in:
  1. E3 ubiquitin-protein ligase parkin
IPR015496
Domain description: Ubiquilin
Occurring in:
  1. E3 ubiquitin-protein ligase parkin

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