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CD1c in complex with phosphatidylcholine

X-ray diffraction
3.21Å resolution
PDB entry 6c15 coloured by chain, front view.
PDB entry 6c15 coloured by chain, side view.
PDB entry 6c15 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: T-cell surface glycoprotein CD1c and Beta-2-microglobulin
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Multimeric state: hetero dimer
Accessible surface area: 17916.35 Å2
Buried surface area: 6692.46 Å2
Dissociation area: 1,347.14 Å2
Dissociation energy (ΔGdiss): 11.26 kcal/mol
Dissociation entropy (TΔSdiss): 11.87 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-151327

Macromolecules

T-cell surface glycoprotein CD1c
Chain: A
Length: 287 amino acids
Theoretical weight: 32.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P29017 (Residues: 19-297; Coverage: 88%)
Gene name: CD1C
Pfam:
InterPro:
CATH:
T-cell surface glycoprotein CD1c in PDB entry 6c15, assembly 1, front view.
T-cell surface glycoprotein CD1c in PDB entry 6c15, assembly 1, side view.
T-cell surface glycoprotein CD1c in PDB entry 6c15, assembly 1, top view.
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Beta-2-microglobulin
Chain: B
Length: 108 amino acids
Theoretical weight: 12.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
Beta-2-microglobulin in PDB entry 6c15, assembly 1, front view.
Beta-2-microglobulin in PDB entry 6c15, assembly 1, side view.
Beta-2-microglobulin in PDB entry 6c15, assembly 1, top view.
Molecule details ›

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