PDBe 6bmm

X-ray diffraction
2.35Å resolution

Structure of human DHHC20 palmitoyltransferase, space group P21


Function and Biology Details

Reaction catalysed:
Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Palmitoyltransferase ZDHHC20 Chains: A, B
Molecule details ›
Chains: A, B
Length: 293 amino acids
Theoretical weight: 34.49 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
  • Canonical: Q5W0Z9 (Residues: 7-299; Coverage: 80%)
Gene name: ZDHHC20
Sequence domains: DHHC palmitoyltransferase

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P21
Unit cell:
a: 86.519Å b: 57.7Å c: 94.098Å
α: 90° β: 115.51° γ: 90°
R R work R free
0.242 0.241 0.26
Expression system: Komagataella pastoris