PDBe 6ff9

X-ray diffraction
2Å resolution

Mutant R280K of human P53

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 193 amino acids
Theoretical weight: 21.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P04637 (Residues: 97-289; Coverage: 49%)
Gene names: P53, TP53
Sequence domains: P53 DNA-binding domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P21
Unit cell:
a: 68.569Å b: 69.445Å c: 83.335Å
α: 90° β: 90.04° γ: 90°
R-values:
R R work R free
0.184 0.182 0.226
Expression system: Escherichia coli