PDBe 6fdk

X-ray diffraction
1.6Å resolution

Structure of Chlamydia trachomatis effector protein Cdu1 bound to ubiquitin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Deubiquitinase and deneddylase Dub1 Chain: A
Molecule details ›
Chain: A
Length: 266 amino acids
Theoretical weight: 30.45 KDa
Source organism: Chlamydia trachomatis 434/Bu
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: B0B9A0 (Residues: 155-401; Coverage: 62%)
Gene names: CTL0247, cdu1
Sequence domains: Ulp1 protease family, C-terminal catalytic domain
Ubiquitin Chain: B
Molecule details ›
Chain: B
Length: 76 amino acids
Theoretical weight: 8.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: P0CG47 (Residues: 153-227; Coverage: 33%)
Gene name: UBB
Sequence domains: Ubiquitin family

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 47.815Å b: 56.937Å c: 60.695Å
α: 90° β: 104.86° γ: 90°
R-values:
R R work R free
0.171 0.17 0.203
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'